(5α)-4,5-Epoxy-3,14-dihydroxymorphinan-6-on
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- CAS-Nr.
- 33522-95-1
- Bezeichnung:
- (5α)-4,5-Epoxy-3,14-dihydroxymorphinan-6-on
- Englisch Name:
- 7,8-Dihydro-14-hydroxy- normorphinone
- Synonyma:
- (-)-Noroxymorphone;Naloxone EP Impurity A;7,8-Dihydro-14-hydroxynormorphinone;EN 3169;Noroxymorphone-d4;NoroxyMorphone HCl;Naloxone HCl Impurity;Naltrexone EP Impurity B;Naltrexone EP Impuirty B;4-Hydroxydihydronormorphinone
- CBNumber:
- CB5927506
- Summenformel:
- C16H17NO4
- Molgewicht:
- 287.32
- MOL-Datei:
- 33522-95-1.mol
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(5α)-4,5-Epoxy-3,14-dihydroxymorphinan-6-on Eigenschaften
- Schmelzpunkt:
- >265°C (dec.)
- Siedepunkt:
- 552.1±50.0 °C(Predicted)
- Dichte
- 1.54±0.1 g/cm3(Predicted)
- Flammpunkt:
- 22℃
- storage temp.
- Controlled Substance, -20°C Freezer
- Löslichkeit
- DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml
- Aggregatzustand
- A crystalline solid
- pka
- 9.20±0.40(Predicted)
- Stabilität:
- Hygroscopic
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
T,F |
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| R-Sätze: |
10-23/24/25-39/23/24/25-11 |
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| S-Sätze: |
36/37-45-16-7 |
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| RIDADR |
UN1230 - class 3 - PG 2 - Methanol, solution |
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| WGK Germany |
1 |
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| DEA Controlled Substances |
CSCN: 9668
CSA SCH: Schedule II
NARC: Yes |
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| Bildanzeige (GHS) |
  
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H225 |
Flüssigkeit und Dampf leicht entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 2 |
Achtung |
![GHS hazard pictograms]() src="/GHS02.jpg" width="20" height="20" /> |
P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 |
| H370 |
Schädigt die Organe. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
P260, P264, P270, P307+P311, P321,P405, P501 |
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| Sicherheit |
| P210 |
Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P311 |
GIFTINFORMATIONSZENTRUM/Arzt anrufen. |
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(5α)-4,5-Epoxy-3,14-dihydroxymorphinan-6-on Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Noroxymorphone (Item No. 15903) is an analytical reference standard that is structurally categorized as an opioid. It is an active metabolite of oxycodone , noroxycodone (Item Nos.
15902 |
20407), and oxymorphone that can be detected in plasma and urine. Noroxymorphone is also an immediate precursor in the synthesis of several opioids, including naltrexone (Item Nos.
15520 |
ISO60192) and naloxone (Item Nos.
15594 |
ISO60191). Noroxymorphone is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.
Chemische Eigenschaften
Off-White to Light Brown Solid
Verwenden
A metabolite of Naloxone and Naltrexone
(5α)-4,5-Epoxy-3,14-dihydroxymorphinan-6-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Morphinan-17-carboxylic acid, 4,5-epoxy-3-[(ethoxycarbonyl)oxy]-14-hydroxy-6-oxo-, ethyl ester, (5α)-
Morphinan-17-carboxylic acid, 7,8-didehydro-4,5-epoxy-6-hydroxy-3-methoxy-, ethyl ester, (5α,6α)-
(5α)-4,5-Epoxy-3,14-dihydroxymorphinan-6-onhydrochlorid
Morphinan-6-one, 17-acetyl-3-(acetyloxy)-4,5-epoxy-14-hydroxy-, (5α)-
6,11b-Ethano-7H-furo[2',3',4',5':4,5]phenanthro[9,8a-d]oxazol-11(11aH)-one, 2-(acetyloxy)-5,5a,9,10-tetrahydro-, (5aR,6R,8aS,11aR,11bS)-
(5α)-4,5-Epoxy-14-hydroxy-3-methoxymorphinan-6-on
(5alpha)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one
Naloxon
Downstream Produkte
(5α)-4,5-Epoxy-3,14-dihydroxymorphinan-6-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 82)Lieferanten
33522-95-1((5α)-4,5-Epoxy-3,14-dihydroxymorphinan-6-on)Verwandte Suche:
- 4,5α-Epoxy-3,14-dihydroxymorphinan-6-one
- (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
- NoroxyMorphone HCl
- Morphinan-6-one,4,5-epoxy-3,14-dihydroxy-, (5a)-
- Noroxymorphone hydrochloride solution
- Methanol(test NoroxymorphoneHCl,100μg/mLasfreebase)
- Naloxone HCl Impurity
- (5alpha)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
- (5a)-4,5-Epoxy-3,14-dihydroxy-morphinan-6-one
- 4-Hydroxydihydronormorphinone
- 7,8-Dihydro-14-hydroxy- normorphinone
- EN 3169
- Naltrexone hydrochloride iMpurity B
- Naltrexone EP Impurity B
- (4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one
- Naltrexone EP Impuirty B
- LTREXONE HYDROCHLORIDE - IMPURITY B
- Naltrexone Impurity 6 Monomer
- Naloxone Impurity 7（Naloxone EP Impurity A）
- Naloxone Hydrochloride Impurit Ⅰ:(5alpha)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
- Naloxone?Hydrochloride EP Impurity A
- Nor Oxymorphone (1.0mg/ml in DMSO)
- Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-, (5α)-
- (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
- Noroxymorphone-d4
- Naloxone Hydrochloride Impurit Ⅰ:(5alpha)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
- 7,8-Dihydro-14-hydroxynormorphinone
- Naloxone EP Impurity A
- (-)-Noroxymorphone
- 4,5α-epoxy-3,14-dihydroxymorphinan-6-one (noroxymorphone)
- Naltrexone EP Impurity B（Naloxone EP Impurity A）
- 33522-95-1
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
