3'-fluoro-3'-deoxyadenosine

75059-22-2

CAS-Nr.: 75059-22-2

Englisch Name:: 3'-fluoro-3'-deoxyadenosine

Synonyma:: 3'-F-3'-rA;3'-fluoro-3'-deoxyadenosine;3'-fluoro-3'-deoxyadenosine;3’-Deoxy-3’-fluoro adenosine;Adenosine, 3'-deoxy-3'-fluoro-;(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol

CBNumber:: CB61333211

Summenformel:: C10H12FN5O3

Molgewicht:: 269.23

MOL-Datei:: 75059-22-2.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 51

3'-fluoro-3'-deoxyadenosine Eigenschaften

Schmelzpunkt:: 211-212 °C

Siedepunkt:: 628.6±65.0 °C(Predicted)

Dichte: 2.01±0.1 g/cm3(Predicted)

pka: 12.45±0.70(Predicted)

InChI: InChI=1S/C10H12FN5O3/c11-5-4(1-17)19-10(7(5)18)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1

InChIKey: QCDAWXDDXYQEJJ-QYYRPYCUSA-N

SMILES: OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H](O)[C@@H]1F

Sicherheit

3'-fluoro-3'-deoxyadenosine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

3'-deoxy-3'-fluoroadenosine can be used as pharmaceutical intermediates for pharmaceutical experimental research.

Biologische Aktivität

3'-Fluoro-3'-deoxyadenosine was active against a broad range of viruses, encompassing both DNA viruses [pox (vaccinia)], single-stranded (+) RNA viruses [picorna (polio, Coxsackie B), toga (sindbis, Semliki Forest)] and double-stranded RNA viruses (reo). Its antiviral activity spectrum, 3'-fluoro-3'-deoxyadenosine, clearly differed from those adenosine analogs known as inhibitors of S-adenosylhomocysteine hydrolase. 3'-Fluoro-3'-deoxyadenosine also proved effective in vivo in inhibiting tail lesion formation in mice inoculated intravenously with vaccinia virus[1].

3'-fluoro-3'-deoxyadenosine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

β-D-Xylofuranoside, methyl 3,5-O-(1-methylethylidene)-

Downstream Produkte

3'-Deoxy-3'-fluoro-N6-benzoyladenosine

3'-fluoro-3'-deoxyadenosine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 51)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10027	58
PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD	0371-55159968 18137130222	haifeng.zhang@pannacean.com	China	387	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58
Nanjing Baifuli Technology Co., Ltd.	+86-15335185688	sales@unisyn.cn	CHINA	332	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
NINGBOBENKANGJS PHARMTECHCO., LTD	+8615990591583 15990591583		CHINA	2029	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4022	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58

3'-fluoro-3'-deoxyadenosine
(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
3'-F-3'-rA
Adenosine, 3'-deoxy-3'-fluoro-
3'-fluoro-3'-deoxyadenosine
3’-Deoxy-3’-fluoro adenosine
75059-22-2