Chinese english Germany Japanese Korea

Dinatrium-[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-(phenylsulfonatoacetamido)-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat

Sulbenicillin sodium Struktur
28002-18-8
CAS-Nr.
28002-18-8
Bezeichnung:
Dinatrium-[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-(phenylsulfonatoacetamido)-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat
Englisch Name:
Sulbenicillin sodium
Synonyma:
sulpelin;kedacillin;lilacillin;sulfocillin;a-Sulfocillin;SULBENICILLIN SODIUM;sulfobenzylpenicillin;sulbenicillindisodium;disodiumsulbenicillin;Sulfonpicillin sodium
CBNumber:
CB6145730
Summenformel:
C16H16N2Na2O7S2
Molgewicht:
458.42
MOL-Datei:
28002-18-8.mol
Request For Quotation

Dinatrium-[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-(phenylsulfonatoacetamido)-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat Eigenschaften

storage temp. 
Inert atmosphere,Room Temperature
Wasserlöslichkeit
Water: 250 mg/mL (545.35 mM)
CAS Datenbank
28002-18-8(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P302+P352 BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Dinatrium-[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-(phenylsulfonatoacetamido)-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Lillacillin,Takeda,Japan,1973

Manufacturing Process

To a suspension of 1.08 parts by weight of 6-aminopenicillanic acid in 8 parts by volume of water is added 1.48 parts by weight of sodium bicarbonate. After the mixture is dissolved, a solution of 1.18 parts by weight of α-sulfophenylacetyl chloride in 10 parts by volume of diethylether is gradually added thereto. The mixture is stirred at a temperature in the neighborhood of 0°C for 1 hour. The aqueous layer is washed twice with 10 parts by volume of portions of ether and adjusted to pH 1.2 with cation exchange resin of polystyrene sulfonic acid type under constant cooling. Then the solution is washed twice with 15 parts by volume of portions of ethyl acetate, followed by extraction twice with 15 parts by volume of portions of n-butanol. The extracts are combined and washed twice with 15 parts by volume of portions of water and, then, extracted with an aqueous solution of sodium bicarbonate. The extract is adjusted to pH 6.5, washed with ether and lyophilized to give the sodium salt of α-sulfobenzylpenicillin. Yield is 1.2 parts by weight.

Therapeutic Function

Antibacterial

Dinatrium-[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-(phenylsulfonatoacetamido)-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

6-Aminopenicillansure

Downstream Produkte

Dinatrium-[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-(phenylsulfonatoacetamido)-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 164)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886
info@dakenam.com China 15928 58
career henan chemical co 		+86-0371-86658258
sales@coreychem.com China 29914 58
HubeiwidelychemicaltechnologyCo.,Ltd 		18627774460
faith@widelychemical.com CHINA 742 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873
 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 47465 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81138252 +86-18789408387
 1057@dideu.com China 3635 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674;
 laboratory@coreychem.com China 30255 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418671
sales@tnjchem.com China 34572 58
Qiuxian Baitai New Material Co., LTD 		+8618330912755
 sale2@hbyalin.com China 1677 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167
 1026@dideu.com China 9409 58

28002-18-8(Dinatrium-[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-(phenylsulfonatoacetamido)-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat)Verwandte Suche:

Carbenicillin 6-(2-Phenylacetamido)penicillansure Natriumcarbonat Natriumgluconat Natrium-[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat N,N'-1,2-Ethandiylbis(N-(carboxymethyl)glycin,Dinatrium-Salz Dimethylphthalat Dimethyl ether Bensulfuron methyl Dimethylfumarat Dimethylsulfid Dinatrium-[2S-(2α,5α,6β)]-6-(carboxylatophenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat Natriumhydroxid N,N-Dimethylacetamid Natriumformiat Natriumchlorid Poly(dimethylsiloxane) Natriumhydrogencarbonat
  • sulbenicillindisodium
  • sulfobenzylpenicillin
  • sulfocillin
  • alpha-sulfobenzylpenicillindisodium
  • sulpelin
  • SULBENICILLIN DISODIUM SALT
  • SULBENICILLIN SODIUM
  • disodium (2s,5r,6r)-3,3-dimethyl-7-oxo-6-[(r)-2-phenyl-2-sulfonatoacetamido]-4-thia-azabicyclo[3.2.0]heptane-2-carboxylate
  • disodium [2S-(2alpha,5alpha,6beta)]-3,3-dimethyl-7-oxo-6-(phenylsulphonatoacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenyl-2-sulfoacetamido)-, disodium salt (8CI)
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylsulfoacetyl)amino]-, disodium salt, (2S,5R,6R)- (9CI)
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylsulfoacetyl)amino]-, disodium salt, [2S-(2a,5a,6b)]-
  • a-Sulfobenzylpenicillin disodium salt
  • a-Sulfobenzylpenicillin sodium salt
  • a-Sulfocillin
  • (2S,5β)-3,3-Dimethyl-7-oxo-6α-[(R)-2-phenyl-2-sulfoacetylamino]-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid disodium salt
  • 6α-[(R)-Phenyl(sodiooxysulfonyl)acetylamino]penicillanic acid sodium salt
  • Sulbenicillin sodiuM Sterile
  • disodiumalpha-sulfobenzylpenicillin
  • disodiumsulbenicillin
  • disodiumsulfobenzylpenicillin
  • kedacillin
  • lilacillin
  • Sulbenicillin (Kedacillin, Sulfocillin)
  • (2S,5R,6R)-3,3-dimethyl-6-(2-phenyl-2-sulfoacetylamino)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid disodium salt
  • Ticarcillin Sodium and Potassium Clavulanate
  • Sulbenicillin Disodium Salt (Mixture of Diastereomers)
  • Sulbenicillin sodium USP/EP/BP
  • Sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenyl-2-sulfonatoacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
  • Sulfonpicillin sodium
  • Sulfobenzillin sodium
  • 28002-18-8
  • C17H19N2Na2O7S
  • C16H16N2NaO7S2
  • C16H16N2Na2O7S2
  • antibiotic
  • API
  • 28002-18-8
Copyright 2019 © ChemicalBook. All rights reserved