Tetrakis(triphenylphosphin)palladium
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- CAS-Nr.
- 14221-01-3
- Bezeichnung:
- Tetrakis(triphenylphosphin)palladium
- Englisch Name:
- Tetrakis(triphenylphosphine)palladium
- Synonyma:
- PD(PPH3)4;TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM(0);etrakis(triphenylphosphine)palladiuM;TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM(O);PALLADIUM (0) TETRAKIS(TRIPHENYLPHOSPHINE);Tetra(triphenylphosphine) palladium;Tetrakis(triphenylphosphine)palladiu;PALLADIUM-TETRAKIS(TRIPHENYLPHOSPHINE);Tetrakis(triphenylphosphine)palladium, tech;Tetrakis(triphenylphosphine)palladium(0), 99.8% (metals basis), Pd 9% min
- CBNumber:
- CB6163934
- Summenformel:
- C72H60P4Pd
- Molgewicht:
- 1155.561844
- MOL-Datei:
- 14221-01-3.mol
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Tetrakis(triphenylphosphin)palladium Eigenschaften
- Schmelzpunkt:
- 103-107 °C
- Dampfdruck
- 0Pa at 25℃
- storage temp.
- 2-8°C
- Löslichkeit
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- Aggregatzustand
- Fine Powder or Platelets
- Farbe
- Bright yellow to khaki
- Wasserlöslichkeit
- insoluble
- Hydrolytic Sensitivity
- 7: reacts slowly with moisture/water
- Sensitive
- Light Sensitive/Air Sensitive
- BRN
- 6704828
- Stabilität:
- Light Sensitive, Moisture Sensitive
- InChIKey
- NANALCPCPBPJAB-UHFFFAOYSA-N
- LogP
- 5.69 at 20℃
- CAS Datenbank
- 14221-01-3(CAS DataBase Reference)
- EPA chemische Informationen
- Palladium, tetrakis(triphenylphosphine)-, (T-4)- (14221-01-3)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Tetrakis(triphenylphosphin)palladium Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
yellow crystals
Verwenden
Tetrakis(triphenylphosphine)palladium(0) is widely used as a catalyst for palladium-catalyzed coupling reactions.
Application
Palladium-Catalyzed Three-Component Reaction for the Synthesis of Imidazolidinones.
Once the Schlenk tube containing K2CO3 (55 mg, 0.40 mmol) is flamed, dried, and filled with argon, Tetrakis(triphenylphosphine)palladium (12 mg, 0.010 mmol), PMB-protected 2,3-allenylamine (37 mg, 0.20 mmol), iodobenzene (58 mg, 0.28 mmol), phenyl isocyanate (36 mg, 0.30 mmol), and CH3CN (4 mL) are added sequentially. The resulting solution is heated to and stirred at 70°C. When the reaction is completed as monitored by TLC, the solvent is evaporated under reduced pressure, and the residue is purified by chromatography on silica gel (petroleum ether : ethyl acetate = 7:1) to afford the corresponding imidazolidione (72 mg, Y. 96%) as an oil.
Reaktionen
- Catalyst for Suzuki coupling of chiral secondary organoboronic esters.
- Palladium-catalyzed SNAr reactions for the synthesis of heteroaryl ethers.
- Catalyst for cross-coupling of a-diazocarbonyl compouns with arylboronic acids.
- Diastereoselective synthesis of trans-1,2-diazetidines.
- Palladium-catalyzed alkynyl iminium ion cyclization.
- Widely used reagent in a variety of transformations including Heck arylation, enyne and diyne cycloisomerization.
- Catalysts for cross-coupling.
läuterung methode
The palladium complex is recrystallised from EtOH. It should not be heated excessively as it dissociates to Pd(PPh3)3 and PdPh3 and then further to Pd(PPh3)2 and PPh3. It is also air sensitive as PPh3 is oxidized to PPh3O. It is stable only for short periods because on exposure to heat or air it turns from yellow to orange and dissociates in solution so the solutions should be used directly. However it can always be prepared freshly by mixing Pd(NO3)2 (2mmols) and PPh3(2mmols) in hot *C6H6 when vigorous evolution of nitric oxide occurs and a solid mass separates. This is collected and crystallised from EtOH. Its cryoscopic constant in *C6H6 (at 0.601g/20mL) corresponds to M 1156 [Malatesta & Angoletti J Chem Soc 1186 1957]. It is a useful catalyst for Suzuki coupling reactions [Trost Tetrahedron 33 2615 1977]. [Beilstein 16 IV 954.] This palladium catalyst bound to a polymer support (~0.06mmol/g) is also commercially available [cf Fenger & LeDrain Tetrahedron Lett 39 4287 1998]. [Beilstein 16 IV 954.]
Tetrakis(triphenylphosphin)palladium Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Tetrakis(triphenylphosphin)palladium Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 695)Lieferanten
14221-01-3(Tetrakis(triphenylphosphin)palladium)Verwandte Suche:
- (beta-4)-palladiu
- Tetrakis (triphenyl phosphene)palladiuM(o)
- Tetrakis(triphenylphosphine)palladiuM(0) >=99.99% trace Metals basis
- Tetrakis[triphenylphosphine]palladium(0), ChemDose? tablets
- Tetrakis(triphenylphosphine)palladium(0) Vetec(TM) reagent grade, 98%
- Tetrakis[triphenylphosphine]palladium(0), ChemDose(TM) tablets Loading: 2mumol per tablet
- Tetrakis(triphenylphosphine)palladiuM(0), 99.8% (Metals basis), Pd 9%
- Tetrakis(tripheny1phosphine)palladium
- etrakis(triphenylphosphine)palladium(0)
- Tetrakis(triphenylphosphine)palladium(0), 99.5% trace metals basis
- TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM(0): 99.9%
- TETRAKIS(TRIPHENYLPHOSPHNE) PALLADIUM (0)
- Tetrakis[triphenylphosphine]palladium(0), ChemDose(R) tablets
- Tetrakis (iphenylphosphine) Pplladium
- Tetrakis(triphenylphosphine)palladium,99% (99.9+%-Pd)
- Tetrakis(triphenylphosphine)palladium(0),99%
- Palladiumhydroxideoncarbon5%Soldonadrybasis
- Tetrakis(triphenylphosphine)palladium(0),Palladium-tetrakis(triphenylphosphine)
- Tetrakis(triphenylphosphine)palladium (O), 99% (99.9+%-Pd)
- Tetrakis(triphenylphosphine)palladiuM(II)
- Tetrakis(triphenylphosphine)palladiuM (0),98% Pd(PPh3)4
- Tetrakis(triphenylphosphine)palladiuM(0), 99.9%, (trace Metal basis)
- Tetrakis(triphenylphosphine)palladium(0)≥ 99.5% (≥ 9% Pd, Assay)
- PS-DVB
- TETRAKIS(TRIPHENYLPHOSPHIN)-PALLADIUM(O)
- TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM
- TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM POLYMER BOUND
- PALLADIUM-TETRAKIS(TRIPHENYLPHOSPHINE) POLYMER-BOUND
- Tetrakis(triphenylphosphin)Palladium
- Terakis(triphenylphosphine)palladium(0)
- Tetrakis(triphenylphosphine)palladium (0), 99%, 9% Pd
- Tetrakis(triphenylphosphine)palladium(0),99%(99.9+%-Pd)
- Palladium, tetrakis(triphenylphosphine)-, (T-4)-
- adium(0)
- phosphine)paL
- Tetrakis(triphenyL
- Pd9.2%Tetrakis(triphenylphosphine palladium
- Tetrakis(triphenylphosphine)palladium,99%
- Tetrakistrifenilfosfina paládio
- Tetrakis(triphenylphosphine)palladium ISO 9001：2015 REACH
- K0545
- Pd TK
- Tetrakis(Triphenylphosphine) Palladium (0) extrapure, 97%
- TETRAKIS (TRIPHENYLPHOSPHINE) PALLADIUM (0) For Synthesis
- Tetrakis(triphenylphosphine)palladium(0), 99.8% (metals basis), Pd 9% min
- Tetrakis(triphenylphosphine) p
- Tetrakis(triphenylphosphine)palladiu
- Tetrakis(triphenylphosphine)palladiuM(0), 99.8%
- etrakis(triphenylphosphine)palladiuM
- Tetrakis(triphenylphosphine)palladium(II),98% Pd(PPh3)4
- Tetra(triphenylphosphine) palladium
- Tetrakis(Triphenylphosphine)Palladium(0) (Metals Basis), Pd 9% Min
- Tetrakis(triphenylphosphine)palladium(0) ,0% [9.2%Pd,Light yellow green powder]
- TETRAKIS-(TRIPHENYLPHOSPHANYL)-PALLADIUM
- TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM(O)
- PALLADIUM-TETRAKIS(TRIPHENYLPHOSPHINE)
- Tetrakis(triphenylphosphine)palladium, tech
- Tetrakis(triphenylphosphine)palladium(0) Store refrigerated Protect from light
