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(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate

(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate Struktur
863329-65-1
CAS-Nr.
863329-65-1
Englisch Name:
(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate
Synonyma:
Sofosbuvir Impurity 124;Sofosbuvir Intermediate 3;Picaridin Impurity 6 (1,2-Propanediol-1-Acetate);3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-2'-methyluridine;3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-2'-C-Methyluridine;(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate;URIDINE, 2'-DEOXY-2'-FLUORO-2'-METHYL-, 3',5'-DIBENZOATE, (2'R)-;2'Deoxy-2'fluoro-2'- Methyl- 3'5'-bis-o- (phenylcarbonyl) uridine;[(2R,3R,4R,5R)-3-Benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-4-methyl-tetrahydrofuran-2-yl;[(2R,3R,4R,5R)-3-Benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-4-methyl-tetrahydrofuran-2-yl]methyl benzoate
CBNumber:
CB62604347
Summenformel:
C24H21FN2O7
Molgewicht:
468.43
MOL-Datei:
863329-65-1.mol
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(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate Eigenschaften

Schmelzpunkt:
256-258℃
Dichte
1.42
pka
9.39±0.10(Predicted)
Wasserlöslichkeit
3.7mg/L
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

RO 2433 Dibenzoate is a related compound of RO 2433 (R637200), a deaminated metabolite of β-D-2''-Deoxy-2''-fluoro-2''-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.

(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 71)Lieferanten
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  • (2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate
  • 2'Deoxy-2'fluoro-2'- Methyl- 3'5'-bis-o- (phenylcarbonyl) uridine
  • ((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-fluoro-4-Methyltetrahydrofuran-2-yl)Methyl benzoate
  • URIDINE, 2'-DEOXY-2'-FLUORO-2'-METHYL-, 3',5'-DIBENZOATE, (2'R)-
  • 3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-2'-C-Methyluridine
  • Sofosbuvir Intermediate 3
  • [(2R,3R,4R,5R)-3-Benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-4-methyl-tetrahydrofuran-2-yl]methyl benzoate
  • 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-2'-methyluridine
  • [(2R,3R,4R,5R)-3-Benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-4-methyl-tetrahydrofuran-2-yl
  • (2R,3R,4R,5R)-2-[(benzoyloxy)methyl]-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-4-methyloxolan-3-yl benzoate
  • Sofosbuvir Impurity 124
  • Picaridin Impurity 6 (1,2-Propanediol-1-Acetate)
  • 863329-65-1
  • Sofosbuvir intermediate
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