1,3-Dihydroxyaceton
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- CAS-Nr.
- 96-26-4
- Bezeichnung:
- 1,3-Dihydroxyaceton
- Englisch Name:
- 1,3-Dihydroxyacetone
- Synonyma:
- DIHYDROXYACETONE;1,3-dihydroxypropan-2-one;Dihyxal;Glycerone;Ketochromin;1,3-Dihydroxypropanone;1,3-DIHYDROXY-2-PROPANONE;2-Propanone, 1,3-dihydroxy-;Otan;Aliphatic ketone
- CBNumber:
- CB6306814
- Summenformel:
- C3H6O3
- Molgewicht:
- 90.08
- MOL-Datei:
- 96-26-4.mol
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1,3-Dihydroxyaceton Eigenschaften
- Schmelzpunkt:
- 75-80 °C
- Siedepunkt:
- 107.25°C (rough estimate)
- Dichte
- 1.1385 (rough estimate)
- Dampfdruck
- 0.002-0.33Pa at 20-50℃
- FEMA
- 4033 | DIHYDROXYACETONE
- Brechungsindex
- 1.4540 (estimate)
- storage temp.
- Store at +2°C to +8°C.
- Löslichkeit
- >112.4 mg/mL in DMSO; >5.09 mg/mL in EtOH with ultrasonic
- pka
- 12.45±0.10(Predicted)
- Aggregatzustand
- powder
- Farbe
- White
- Geruch (Odor)
- at 100.00 %. minty
- Geruchsart
- minty
- Wasserlöslichkeit
- >250 g/L (20 ºC)
- JECFA Number
- 1716
- Stabilität:
- Stable. Combustible. Hygroscopic.
- LogP
- -1.95 at 20℃
- Oberflächenspannung
- 68.85mN/m at 1g/L and 20℃
- CAS Datenbank
- 96-26-4(CAS DataBase Reference)
- NIST chemische Informationen
- 2-Propanone, 1,3-dihydroxy-(96-26-4)
- EPA chemische Informationen
- 2-Propanone, 1,3-dihydroxy- (96-26-4)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| S-Sätze: |
24/25 |
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| HS Code |
29141900 |
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| Giftige Stoffe Daten |
96-26-4(Hazardous Substances Data) |
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| Toxizität |
CHROMELIN ? DIHYDROXYACETONE ? 1,3DIHYDROXYACETONE ? 1,3-DIHYDROXYPROPANONE ? DIHYXAL ? NSC-24343 ? OTAN ? OXATONE ? SOLEAL ? 2PROPANONE, 1,3-DIHYDROXY- ? TRIULOSE ? VITICOLOR |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
| P321 |
Besondere Behandlung |
| P332+P313 |
Bei Hautreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
| P362 |
Kontaminierte Kleidung ausziehen und vor erneutem Tragen waschen. |
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1,3-Dihydroxyaceton Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white powder
Occurrence
A derivative of naturally occurring starch
Verwenden
1,3-Dihydroxyacetone can be used as artificial tanning agent.
Definition
ChEBI: Dihydroxyacetone is a ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones. It has a role as a metabolite, an antifungal agent, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a ketotriose and a primary alpha-hydroxy ketone.
synthetische
1,3-dihydroxyacetone (DHA) is prepared by acetalization, oxidation, and hydrolysis of glycerol. Usually produced commercially from Bacillus macerans or Bacillus circulans fermentation of starch or starch
hydrolysate
Allgemeine Beschreibung
Dihydroxyacetone (DHA) is a browning ingredient widely used in cosmetics such as sunless tanning formulations. It participates in a chemical staining reaction called Milliard reaction in which it reacts with the amino groups of proteins to result in a mixture of high molecular weight pigments.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Sicherheitsprofil
Mutation data reported. When heated to decompositionit emits acrid smoke and irritating vapors.
Sicherheit(Safety)
Cells that were treated with 1,3-Dihydroxyacetone (DHA) showed dose- and time-dependent changes that included cytoplasmic budding, chromatin condensation, and cell detachment. There was a significant decrease in cell proliferation after 24 hours of DHA exposure. After exposure to a 5% DHA solution for 21 days, epidermal thickening and dermatitis of the skin were noted in laboratory animals. After 42 days of treatment with the same solution, hyperplastic and dyskeratotic changes and moderate inflammatory reactions were seen. Long-lasting topical tanning products contain the sugars DHA or erythrulose, which cause a "Maillard reaction" when contacting proteins in the outer layers of the stratum corneum and epidermis. This reaction happens when free amino acids from skin proteins combine with DHA in the stratum corneum. This combination creates the tanned appearance of skin. Results are generally seen within a few hours of application. UV light exposure is not needed to initiate this chemical reaction[1].
1,3-Dihydroxyaceton Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1,3-Dihydroxyaceton Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 533)Lieferanten
96-26-4(1,3-Dihydroxyaceton)Verwandte Suche:
- Chromelin
- NSC-24343
- Oxantin
- Oxatone
- Protosol
- Soleal
- Triulose
- Viticolor
- 1,3-DIHYDROXYACETONE
- 1,3-DIHYDROXY-2-PROPANE
- 1,2-DIHYDROXY-2-PROPANONE
- DIHYDROXYACETONE CRYSTALLINE
- 1,3-Dihydroxyaceton
- 1,3-DIHYDROXYACETONE (DHA)
- Dihydroxyacetone ,98%
- Dihydroxyacetone (250 mg)
- 1,1-Dihydroxy-propan-2-one
- 1,3-Dihydroxyacetone, 98%+
- 1,3-Dihydroxyacetone Monomer
- DIHYDROXYACETONE FOR SYNTHESIS
- Nizatidine Impurity 3
- Bis(hydroxymethyl)ketone
- dihydroxyacetone (monomer)
- 1,3-DIHYDROXYACETONE (DHA) Cas RN 96-26-4
- 1,3-Dihydroxyacetone D4
- PROPANE-1,3-DIOL-2-ONE
- 1,3-dihydroxy-2-propanon
- 1,3-Dihydroxydimethyl ketone
- 1,3-Dihydroxypropanone
- Aliphatic ketone
- Dihyxal
- Ketochromin
- Otan
- DIHYDROXYACETONE
- 1,3-DIHYDROXYACTONE
- 1,3-DIHYDROXY-2-PROPANONE
- 2-Propanone, 1,3-dihydroxy-
- 1,3-dihydroxypropan-2-one
- Glycerone
- 3-Dihydroxyacetone
- 1,3 Dihydroxypropan-2-One(Dihydroxyacetone)
- 4-Butylresorcino
- DHA (Dihydroxyacetone)
- Dihydroxyacetone, DHA
- Hexane 110-54-3
- Glycerol Impurity 15
- 96-26-4
- Pharmaceutical intermediates
- Imidazoles
- 96-26-4
- bc0001
