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4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Struktur
99010-64-7
CAS-Nr.
99010-64-7
Englisch Name:
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
Synonyma:
cas 99010-64-7;Imiquimod USP RC C;Imiquimod Impurity-C;DesaMino ChloroiMiquiMod;1H-Imidazo[4,5-c]quinoline,;IMiquiMod Related CoMpound C;Imiquimod USP Related Compound C;4-Chloro-1-isobutyl-1H-imidazo[4,5-;1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(;4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE
CBNumber:
CB6449735
Summenformel:
C14H14ClN3
Molgewicht:
259.73
MOL-Datei:
99010-64-7.mol
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4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Eigenschaften

Schmelzpunkt:
139-140 °C(Solv: isopropanol (67-63-0))
Siedepunkt:
427.5±48.0 °C(Predicted)
Dichte
1.29±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Löslichkeit
Chloroform (Sparingly), Methanol (Slightly)
Aggregatzustand
Solid
pka
3.15±0.30(Predicted)
Farbe
White to Off-White
CAS Datenbank
99010-64-7(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
HS Code  2934990002
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is a chemical product that has been used as a photosynthetic activator in weed science and pest control. It has been shown to significantly increase the growth rate of wheat, soybean, and oilseed crops. It is also effective at controlling weeds by inhibiting their ability to produce chlorophyll, thereby preventing them from photosynthesizing. 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline has also been shown to be an effective herbicide for agricultural use.

Verwenden

Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.

Synthese

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is prepared by the reaction of 2-chloro-N4-(2-methylpropyl)quinoline-3,4-diamine and orthoformic acid triethyl ester. The specific synthesis steps are as follows:
A suspension of 2-chloro-N4 -(2-methylpropyl)-3,4-quinolinediamine (35 g) and triethylorthoformate (52.3 g, 2.5 eq) was heated at 145° C. for 10 h, during which time ethanol was removed by distillation. The resulting mixture was cooled to room temperature and the solid was removed by filtration. The solid was dissolved in hydrochloric acid (100 mL, 4N). The resulting solution was added to a solution of sodium hydroxide. The precipitate was filtered and washed with water to afford the product 4-chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline in 92% yield.
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline synthesis

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 173)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806
 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886
info@dakenam.com China 15928 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497
sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714
 fandachem@gmail.com China 9348 55
Shanxi Naipu Import and Export Co.,Ltd 		+86-13734021967 +8613734021967
 kaia@neputrading.com China 1011 58
career henan chemical co 		+86-0371-86658258
sales@coreychem.com China 29914 58
NINGBO INNO PHARMCHEM CO., LTD. 		13867897135
sales@nbinno.com CHINA 925 58
Shanghai Arbor Chemical Co., Ltd. 		021-60451682
act@arborchemical.com CHINA 906 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715
 admin@nexconn.com China 10248 58

99010-64-7()Verwandte Suche:

Chloromethyl isopropyl carbonate 1-Chlor-2,3-epoxypropan 1-Methylimidazol 3-Methylbutanon Chlordifluormethan Chloressigsäure
  • 4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE
  • 4-CHLORO-1-ISOBUTYL-1H-IMIDAZOBEN[4,5-C]QUINOLINE
  • 1-[2-METHYLPROPYL]-1H-2-CHLOROIMIDAZO-[4,5-C]QUINOLINE
  • 1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(2-METHYLPROPYL)
  • 4-Chloro-1-(2-methylpropyl)-1H-imidazo-(4,5c)quinolinone
  • 2-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINONE
  • 1H-Imidazo[4,5-c]quinoline,
  • 4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE
  • 1H-Imidazo[4,5-c]quinoline, -chloro-1-(2-methylpropyl)-
  • 1H-Imidazo[4,5-c]quinolinone,2-chloro-1-(2-methylpropyl)
  • Imiquimod Related Compound C (25 mg) (4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline)
  • 1-H-IMIDAZO[4,5-C]QUINOLINONE,4-CHLORO-1-(2-METHYL PROPYL)
  • IMiquiMod Related CoMpound C
  • DesaMino ChloroiMiquiMod
  • 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline###4-Chloro-1-(2-methylpropyl)-1H-imidazole[4,5-c]quinoline
  • 1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(
  • 4-chloro-1-(2-methylpropyl)imidazo[4,5-c]quinoline
  • Imiquimod USP Related Compound C
  • 4-Chloro-1-isobutyl-1H-imidazo[4,5-
  • Imiquimod USP RC C
  • Imiquimod Impurity 3 (Imiquimod Related Compound C)
  • Imiquimod Impurity-C
  • Imiquimod Related Compound C (4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline) (1338346)
  • 4-CHLORO-1-ISOBUTYL-1H-IMIDAZO (4,5'D)QUINOLINE
  • cas 99010-64-7
  • 99010-64-7
  • C14H14ClN3
  • Quinolines, Quinazolines and derivatives
  • Intermediates of Imiquimod
  • API intermediates
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