Autocamtide-2 Related Inhibitory Peptide - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
Non-phosphorylatable analog of Autocamtide-2 (Cat. No.
189475) that acts as a highly specific and potent inhibitor of calmodulin-dependent protein kinase II (IC
50 = 40 nM). It is about 50 times more potent than [Ala
286]-CaM kinase II Inhibitor, 281-301 (Cat. No.
208710). Has no effect on PKA, PKC, and CaM kinase IV. Blocks Ca
2+-induced insulin secretion from electropermeabilized islets.
Biochem/physiol Actions
Target IC50: 40 nM against calmodulin-dependent protein kinase II
Autocamtide-2 Related Inhibitory Peptide - Calbiochem Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte