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β-Elemonic Acid

β-Elemonic Acid Struktur
28282-25-9
CAS-Nr.
28282-25-9
Englisch Name:
β-Elemonic Acid
Synonyma:
β-Elemonic;Beta-EleMonic;elemonic acid;β-deMonic acid;β-demonic-acid;B-ELEMONIC ACID;β-Elemonic acid;β-Elemonic acid;Elemadienonic acid;BETA-ELEMONIC ACID
CBNumber:
CB6737997
Summenformel:
C30H46O3
Molgewicht:
454.68
MOL-Datei:
28282-25-9.mol
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β-Elemonic Acid Eigenschaften

Schmelzpunkt:
224-225°C
Siedepunkt:
565.2±50.0 °C(Predicted)
Dichte
1.07
storage temp. 
2-8°C
Löslichkeit
DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
Aggregatzustand
A crystalline solid
pka
4.65±0.10(Predicted)

Sicherheit

β-Elemonic Acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 μM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 μM) in vitro.

Verwenden

β-Elemonic Acid inhibits cell proliferation of human lung adenocarcinoma A549 cells and role of MAPK, ROS activation and glutathione depletion. Elemonic acid is also a Pin1 inhibitors.

β-Elemonic Acid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

β-Elemonic Acid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 139)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Zheyan Biotech Co., Ltd. 		18017610038
zheyansh@163.com CHINA 3620 58
Chengdu Greenpure Biopharma CO.,Ltd 		18283602253
jancyzheng@gcgreenpure.com China 952 58
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083
 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd. 		+8618080483897
 sales@biopurify.com China 3424 58
Xi'an Kono chem co., Ltd., 		029-86107037 13289246953
 info@konochemical.com China 2995 58
Shaanxi Pioneer Biotech Co., Ltd . 		+8613259417953
 sales@pioneerbiotech.com China 3000 58
Shanghai Standard Technology Co., Ltd. 		18502101150
ft-sales@nature-standard.com CHINA 1923 58
career henan chemical co 		+86-0371-86658258 15093356674;
 factory@coreychem.com China 29826 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-519-519-85557386
marketing1@neostarunited.com China 8349 58
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879
 sales@chemnorm.com CHINA 2935 58

28282-25-9()Verwandte Suche:

Citronellsäure Fettsuren, C16-18- und C18-ungesttigt 2,2,4,6,6-Pentamethylhept-3-en
  • BETA-ELEMONIC ACID
  • Elemadienonic acid
  • Beta-EleMonic
  • 3-OXOTIRUCALLA-8,24-DIEN-21-OIC ACID
  • β-deMonic acid
  • (13α,14β,17α,20S)-3-Oxolanosta-8,24-dien-21-oic acid
  • B-ELEMONIC ACID
  • (13α,14β,17α,20S)-3-Oxo-5α-lanosta-8,24-dien-21-oic acid
  • (20S)-3-Oxoeupha-8,24-diene-21-oic acid
  • 3-Oxo-5α-tirucalla-8,24-dien-21-oic acid
  • (13alpha,14beta,17alpha,20S)-3-Oxolanosta-8,24-dien-21-oic acid
  • 3-Ketotirucalla-8,24-dien-21-oic acid
  • 3-Oxo-8,24-tirucalledien-21-oic acid
  • 3-Oxotirucallenoic acid
  • 3-Oxotirucallic acid
  • β-Elemonic acid
  • β-Elemonic acid, 98%, from Canarium album (Lour.) Raeusch.
  • β-Elemonic
  • Lanosta-8,24-dien-21-oic acid, 3-oxo-, (13α,14β,17α,20S)-
  • β-demonic-acid
  • β-Elemonic acid
  • elemonic acid
  • 28282-25-9
  • C30H46O3
  • Triterpenoids
  • Tri-Terpenoids
  • reagent
  • standard substance
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