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ailanthone

981-15-7

CAS-Nr.: 981-15-7

Englisch Name:: ailanthone

Synonyma:: ailanthone;Δ13-Dehydrochaparrinone;13,21-Didehydrochaparrinone;2H-1,11c-(Epoxymethano)phenanthro[10,1-bc]pyran-5,10(3H,6aH);(1beta,11alpha,12alpha)-1,11,12-trihydroxy-11,20-epoxypicras...;11β,20-Epoxy-1β,11,12α-trihydroxypicrasa-3,13(21)-diene-2,16-dione;(1β,11β,12α)-11,20-Epoxy-1,11,12-trihydroxypicrasa-3,13(21)-diene-2,16-dione;Picrasa-3,13(21)-diene-2,16-dione,11,20-epoxy-1,11,12-trihydroxy-, (1b,11b,12a)-;Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1β,11β,12α)-

CBNumber:: CB71327541

Summenformel:: C20H24O7

Molgewicht:: 376.4

MOL-Datei:: 981-15-7.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 136

ailanthone Eigenschaften

Schmelzpunkt:: 235-237 °C

Siedepunkt:: 641.0±55.0 °C(Predicted)

Dichte: 1.47

storage temp.: Sealed in dry,Store in freezer, under -20°C

Löslichkeit: DMSO:100.0(Max Conc. mg/mL);265.67(Max Conc. mM)

Aggregatzustand: A crystalline solid

pka: 11.85±0.70(Predicted)

LogP: -0.760 (est)

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

Bildanzeige (GHS)

Alarmwort

Achtung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H300	Lebensgefahr bei Verschlucken.	Akute Toxizität oral	Kategorie 2	Achtung	src="/GHS06.jpg" width="20" height="20" />	P264, P270, P301+P310, P321, P330,P405, P501

Sicherheit

ailanthone Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ailanthone is a quassinoid that has been found in Ailanthus and has diverse biological activities. It is active against the P. falciparum strains HB-3 and Dd-2 in vitro (IC₅₀s = 0.003 and 0.037 μg/ml, respectively). Ailanthone is phytotoxic, inhibiting radish seed germination by 88% when used at a concentration of 1 mM. It inhibits dihydrotestosterone-induced androgen receptor transcriptional activity (IC₅₀ = 69 nM in a reporter assay), as well as the growth and colony formation of LNCaP and 22RV1 androgen receptor-expressing cells, but not androgen receptor-negative PC3 and DU145 cells, when used at a concentration of 0.1 μM. Ailanthone (2 mg/kg) reduces tumor volume in 22Rv1, LNCaP, and VCaP castration-resistant prostate cancer (CRPC) mouse xenograft models.

ailanthone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ailanthone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 136)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58

981-15-7()Verwandte Suche:

Dikaliumdihydrogen-15α-hydroxy-2β-[[2-O-isovaleryl-3,4-di-O-sulfonato-β-D-glucopyranosyl]oxy]kaur-16-en-18,19-dioat (1α,2β,5α)-2-Methyl-5-(1-methylvinyl)cyclohexylacetat Octahydro-2H-1-benzopyran-2-on (1α,2β,5α)-2-Methyl-5-(1-methylvinyl)cyclohexan-1-ol Propylcyclohexanacetat

11β,20-Epoxy-1β,11,12α-trihydroxypicrasa-3,13(21)-diene-2,16-dione
13,21-Didehydrochaparrinone
ailanthone
Picrasa-3,13(21)-diene-2,16-dione,11,20-epoxy-1,11,12-trihydroxy-, (1b,11b,12a)-
Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1β,11β,12α)-
(1beta,11alpha,12alpha)-1,11,12-trihydroxy-11,20-epoxypicras...
2H-1,11c-(Epoxymethano)phenanthro[10,1-bc]pyran-5,10(3H,6aH)
(1β,11β,12α)-11,20-Epoxy-1,11,12-trihydroxypicrasa-3,13(21)-diene-2,16-dione
Δ13-Dehydrochaparrinone
981-15-7
Diterpenoids