Pentan-1-ol Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
PHYSIKALISCHE GEFAHREN
Die Dämpfe sind schwerer als Luft und können sich am Boden ausbreiten. Fernzündung möglich. Die Dämpfe mischen sich leicht mit Luft. Bildung explosionsfähiger Gemische.
CHEMISCHE GEFAHREN
Reagiert sehr heftig mit Oxidationsmitteln. Greift viele Alkali- und Erdalkalimetalle unter Bildung entzündlichen/explosionsfähigen Gases an (Wasserstoff, s. ICSC-Nr. 0001.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK: 20 ppm, 73 mg/m? Spitzenbegrenzung: überschreitungsfaktor I(4); Schwangerschaft: Gruppe C (DFG 2008).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation der Dämpfe oder des Aerosols, über die Haut und durch Verschlucken.
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz reizt die Augen, die Haut und die Atemwege. Möglich sind Auswirkungen auf das Zentralnervensystem mit nachfolgender Depression. Exposition gegenüber sehr hohen Konzentrationen kann zu Bewusstlosigkeit führen.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Wiederholter oder andauernder Hautkontakt kann Dermatitis hervorrufen.
LECKAGE
Zündquellen entfernen. Ausgelaufene Flüssigkeit in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. NICHT in die Kanalisation spülen. Persönliche Schutzausrüstung: Atemschutzfilter für organische Gase und Dämpfe.
R-Sätze Betriebsanweisung:
R10:Entzündlich.
R20:Gesundheitsschädlich beim Einatmen.
R37:Reizt die Atmungsorgane.
R66:Wiederholter Kontakt kann zu spröder oder rissiger Haut führen.
S-Sätze Betriebsanweisung:
S46:Bei Verschlucken sofort ärztlichen Rat einholen und Verpackung oder Etikett vorzeigen.
Beschreibung
1-Pentanol is a monohydroxy alcohol. It is a colorless liquid with a characteristic odor. Its combustion properties have been studied as it shows promising features to be an alternative to gasoline and diesel fuels. The conversion of 1-pentanol to di-n-pentyl ether (DNPE) in liquid phase at 423K in a batch reactor using ion exchange resins as catalysts.
Chemische Eigenschaften
1-Pentanol is a clear, colorless liquid at ambient temperatures.The air odor detection level (lowest perceptible level) was
reported as 10 ppm for 1-pentanol .
Occurrence
Reported found in banana, sweet cherry, cranberry, bourbon, vanilla, rice bran and Brazil nut.
Verwenden
Raw material for pharmaceutical preparations;organic synthesis solvent.
1-Pentanol is used as a key starting material in the production of dichloro-acetic acid pentyl ester, 2-methyltetrahydrofuran, di-n-penyl ether (DNPE), pentyl butyrate and amyl acetate. As a solvent, it is used for coating CDs and DVDs. It has been considered to be a replacement for gasoline and diesel fuels due to its combustion properties. Further, it is used as a reagent to prepare derivatives of ferulic acid and caffeic acid, which shows anticancer properties.
Vorbereitung Methode
1-Pentanol is made primarily by the oxo process, which
involves the reaction of butenes with carbon monoxide and hydrogen in the presence of a catalyst, followed by
hydrogenation. 1-Pentanol is used as a solvent,
as a chemical intermediate for esters, and as a food additive
and flavoring substance. The primary routes
of industrial exposure are by dermal contact and inhalation.
Definition
ChEBI: An alkyl alcohol that is pentane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It has been isolated from Melicope ptelefolia.
Allgemeine Beschreibung
A colorless liquid with a mild to moderately strong odor. Less dense than water. Flash point 91°F. Boiling point 280°F. Vapors heavier than air. Moderately toxic by ingestion. Vapors may irritate skin and eyes. Used as a solvent and to make other chemicals.
Pentanol is incompatible with strong oxidising agents, alkali metals, alkaline earth metals, halogens, hydrogen trisulphide, acids, acetaldehyde, acid anhydrides, acid chlorides, lithium aluminium hydride, isocyanates, dialkylmagnesiums, n-halomides, ethylene oxide, hypochlorous acid, hydrogen peroxide and sulphuric acid, nitrogen tetraoxide, nitryl hypochlorite, permonosulphuric acid, and tri-isobutyl aluminium.
Air & Water Reaktionen
Highly flammable. Soluble in water.
Reaktivität anzeigen
Moderately toxic, flammable if exposed to powerful oxidizers. Incompatible with oxidizing materials, hydrogen trisulfide [Sax, 9th ed., 1996, p. 224].
Hazard
Lower explosive level in air 1.2% by volume. Moderate fire risk.
Health Hazard
Irritation of skin, eyes, and respiratory tract; headache and vertigo; dyspnea and cough; nausea, vomiting, and diarrhea. Double vision, deafness, delirium, and occasionally fatal poisoning, preceded by severe nervous symptoms, have been reported. Coma, glycosuria, and methemoglobinemia can occur.
Brandgefahr
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Sicherheitsprofil
Moderately toxic by
ingestion and skin contact. An eye and
upper respiratory irritant by inhalation. A
severe skin and eye irritant. Ingestion can cause headache, nausea, vomiting, delirium,
and methemoglobin formation. Mutation
data reported. Extremely flammable if
exposed to heat, flame, or powerful
oxiduers. Moderately explosive when
exposed to flame. Incompatible with
oxidzing materials, hydrogen trisulfide. To
fight fire, use alcohol foam, dry chemical.
mögliche Exposition
(n-isomer); Suspected reprotoxic hazard,
Primary irritant (w/o allergic reaction), (iso-, primary):
Possible risk of forming tumors, Primary irritant (w/o allergic
reaction), (sec-, active primary-, and other isomers)
Primary irritant (w/o allergic reaction). Used as a solvent in
organic synthesis and synthetic flavoring, pharmaceuticals,
corrosion inhibitors; making plastics and other chemicals;
as a flotation agent. The (n-isomer) is used in preparation
of oil additives, plasticizers, synthetic lubricants, and as a
solvent.
Versand/Shipping
UN2811 Pentanols, Hazard Class: 3; Labels: 3-
Flammable liquid. UN1987 Alcohols, n.o.s., Hazard Class:
3; Labels: 3-Flammable liquid.
läuterung methode
Dry 1-pentanol with anhydrous K2CO3 or CaSO4, filter and fractionally distil it. It has also been treated with 1-2% of sodium and heated at reflux for 15hours to remove water and chlorides. Traces of water can be removed from the near-dry alcohol by refluxing it with a small amount of sodium in the presence of 2-3% n-amyl phthalate or succinate followed by distillation (see ethanol). Small amounts of amyl alcohol have been purified by esterifying with p-hydroxybenzoic acid, recrystallising the ester from CS2, saponifying with ethanolic-KOH, drying with CaSO4 and fractionally distilling [Olivier Recl Trav Chim Pays-Bas 55 1027 1936]. [Beilstein 1 IV 1640.]
Inkompatibilitäten
Forms an explosive mixture with air.
Contact with strong oxidizers and hydrogen trisulfide may
cause fire and explosions. Incompatible with strong acids.
Violent reaction with alkaline earth metals forming hydrogen,
a flammable gas.
Waste disposal
Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator
equipped with an afterburner and scrubber. All federal,
state, and local environmental regulations must be
observed.
Pentan-1-ol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-(2-PYRROLIDINOETHYL)PIPERAZINE
Pentylnitrit ,,Amylnitrit''
6-Phenyl-1,3,5-triazin-2,4-diamin
Valeriansure
Vanillinsure
4-CHLORO-1,3-DIMETHYLPYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID
Maleinsäureanhydrid
Buttersure
1,3-Dimethyl-1H-pyrazol-5-amine
Dipentylphthalat
Pentylformiat
1-Brompentan
1-Iodpentan
Pentylacetat
1-Piperazinylpyrazin
Dipentylether
Pentyloctanoat
5-Bromo-1,3-dimethyl-1H-pyrazole
6-Butoxy-1H-purin
Pentylbutyrat
1H-Pyrazolo[3,4-b]pyridine-3-carboxylicacid(9CI)
3-Amino-5-methylpyrazole
Valeraldehyd
5-ISOTHIOCYANATO-1,3-DIMETHYL-1H-PYRAZOLE
Kalium-O-pentyldithiocarbonat
