Veratrumaldehyd Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R38:Reizt die Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R36/38:Reizt die Augen und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Veratraldehyde is a crystalline solid (mp 44.5–45°C) with a woody, vanillalike
odor.
Veratraldehyde can be prepared by methylation of vanillin. It is used in oriental
and warm, woody fragrances, as well as in flavor compositions for vanilla notes. It
is an intermediate in, for example, the synthesis of pharmaceuticals.
Occurrence
Reported among the constituents of the essential oils of Cymbopogon javanensis and Eryngium poterium. Also
reported found in raspberry, ginger, peppermint oil, Bourbon vanilla and mastic gum oil.
Verwenden
Veratraldehyde was used in the preparation of 4-chloromethyl-2-(dimethoxyphenyl)-1,3-dioxolane. It was used in the synthesis of (+)-lithospermic acid, having anti-HIV activity. It forms 1:1 inclusion complexes with cyclodextrins. It reacts with 3-acetyl-2,5-dimethythiophene to yield chalcone dye, (2E)-3-(3,4-Dimethoxyphenyl)-1-(2,5-dimethylthiophen-3-yl)prop-2-en-1-one.
synthetische
Prepared from vanillin by methylation of vanillin with dimethylsulfate under mildly alkaline conditions.
Allgemeine Beschreibung
Needles or chunky light peach powder. Has an odor of vanilla beans.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
Veratraldehyde is incompatible with strong oxidizing agents and strong bases. . Veratraldehyde is an aldehyde. Aldehydes are readily oxidized to give carboxylic acids. Flammable and/or toxic gases are generated by the combination of aldehydes with azo, diazo compounds, dithiocarbamates, nitrides, and strong reducing agents. Aldehydes can react with air to give first peroxo acids, and ultimately carboxylic acids. These autoxidation reactions are activated by light, catalyzed by salts of transition metals, and are autocatalytic (catalyzed by the products of the reaction).
Brandgefahr
Veratraldehyde is probably combustible.
läuterung methode
Crystallise the ether from diethyl ether, pet ether, CCl4 or toluene. [Beilstein 8 IV 1765.]
Veratrumaldehyd Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
6,7-Dimethoxy-2,4-Quinazolinedione
B-(3,4-DIMETHOXYPHENYL)-A-CYANOPROPIONALDEHYDE DIMETHYLACETAL
Diaveridin
7-Hydroxy-6-methoxy-3,4-dihydroisoquinoline
1-(3,4-Dimethoxyphenyl)aceton
3-PHENYLUMBELLIFERONE
3,4-Dimethoxyphenylessigsure
Methyldopa
Fenoldopam
3,4-Dimethoxybenzylalkohol
3,4-Dihydroxyphenylessigsure
SINENSETIN
2,6-Bis-(3,4-Dimethoxyphenylmethylene)-Cyclohexanone
