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RUGULOSIN

RUGULOSIN Struktur
23537-16-8
CAS-Nr.
23537-16-8
Englisch Name:
RUGULOSIN
Synonyma:
RUGULOSIN;Nsc160880;NSC 249990;Rugulosin A;(+)-Rugulosin;(+)-RUGULOSIN;(+)-(1S,1'S,2R,2'R,3S,3'S,9AR,9'AR)-RUGULOSIN;(+)-Rugulosin, (1S,1S,2R,2R,3S,3S,9aR,9aR)-Rugulosin, (2R,2R)-Rugulosin;5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-;5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)-
CBNumber:
CB7701377
Summenformel:
C30H22O10
Molgewicht:
542.49
MOL-Datei:
23537-16-8.mol
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RUGULOSIN Eigenschaften

Schmelzpunkt:
293℃ (decomposition)
Siedepunkt:
535.95°C (rough estimate)
Dichte
1.3164 (rough estimate)
Brechungsindex
1.5376 (estimate)
storage temp. 
Store at -20°C
Löslichkeit
DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
Aggregatzustand
A solid
pka
4.20±1.00(Predicted)
IARC
3 (Vol. 40, Sup 7) 1987
EPA chemische Informationen
5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)- (23537-16-8)

Sicherheit

HS Code  29419000

RUGULOSIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

(+)-Rugulosin is a pigment and mycotoxin produced by certain fungi. It inhibits HIV-1 integrase activity with IC50 values of 19 and 25 μM in coupled and strand transfer assays, respectively. It also inhibits ribonuclease H in rat liver by 83% at a concentration of 157 μM and ribonucleases H1, H2, and H3 in T. pyriformis by 100, 99, and 100%, respectively, at a concentration of 313 μM. (+)-Rugulosin leads to hepatic injury and liver cell hyperplasia in mice when administered in the diet. It is cytotoxic to insect cells but not mammalian C6/36, L929, and HepG2 cells (ID50s = 1.2, >200, 23.7, and >200 μg/ml, respectively).

Verwenden

(+)-Rugulosin is an intense yellow pigment produced by some species of Penicillium, Aspergillus and the fungal symbiotants of some lichens. (+)-Rugulosin shows antibacterial and insecticidal activity and has found application as a bioinsecticide, notably as the active secondary metabolite in endophytic fungi of seedlings.

RUGULOSIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

RUGULOSIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 29)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences 		+16314854226
 inquiry@bocsci.com United States 19743 58
TargetMol Chemicals Inc. 		+1-781-999-5354
support@targetmol.com United States 19973 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 52927 58
Shanghai Tauto Biotech Co., Ltd. 021-51320588
tauto@tautobiotech.com China 3989 66
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9709 58
Lynnchem 86-(0)29-85992781 17792393971
 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890
 info@novachemistry.com United Kingdom 4381 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684
 sales@rrkchem.com China 55717 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11289 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829
sales@mitachieve.com China 8864 58

23537-16-8()Verwandte Suche:

1,2,3,4-Tetrahydro-5-hydroxynaphthalin-1-on 3,4-Dihydro-7-methylnaphthalin-1(2H)-on 1,6-Diphenylhexan-1,6-dion 2,4-Dimethylcyclohex-3-en-1-carbaldehyd 1,2,3,4-Tetrahydro-2-methylnaphthalin-1-on 2-Isopropyl-5-methylhex-2-enal Cycloocta-1,5-dien 3,4-Dihydro-6-methylnaphthalin-1(2H)-on 1,5-Dimethylcycloocta-1,5-dien cis-Cyclooctan-1,5-diol
  • (+)-RUGULOSIN
  • RUGULOSIN
  • (+)-(1S,1'S,2R,2'R,3S,3'S,9AR,9'AR)-RUGULOSIN
  • (+)-Rugulosin, (1S,1S,2R,2R,3S,3S,9aR,9aR)-Rugulosin, (2R,2R)-Rugulosin
  • 5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-
  • 5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, [5as-(5ar*,6S*,13ar*,14S*,17R*,18S*,19S*,20R*)]-
  • Nsc160880
  • NSC 249990
  • Rugulosin A
  • 5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)-
  • (+)-Rugulosin
  • 23537-16-8
  • Antibiotic
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