ORIENTIN
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- CAS-Nr.
- 28608-75-5
- Englisch Name:
- ORIENTIN
- Synonyma:
- LUTEOLIN-8-C-GLUCOSIDE;Polygonin;Luteolin 8-C-β-D-glucopyranoside;lutexin;ORIENTIN;ORIENTINE;Aids026706;Aids-026706;ORIENTIN(P);ORIENTIN(SH)
- CBNumber:
- CB7710333
- Summenformel:
- C21H20O11
- Molgewicht:
- 448.38
- MOL-Datei:
- 28608-75-5.mol
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ORIENTIN Eigenschaften
- Schmelzpunkt:
- 260-285°C
- Siedepunkt:
- 816.1±65.0 °C(Predicted)
- Dichte
- 1.759±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- Löslichkeit
- 1 M NaOH: soluble1mg/mL, clear, yellow-orange
- pka
- 6.24±0.40(Predicted)
- Aggregatzustand
- powder
- Farbe
- yellow
- Stabilität:
- Hygroscopic
- LogP
- 1.580 (est)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| S-Sätze: |
24/25 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
DJ3009300 |
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| HS Code |
29389090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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ORIENTIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Orientin is a flavone glycoside originally isolated from
P. orientale that has diverse biological activities, including antioxidant, antibacterial, and anti-inflammatory properties. Orientin scavenges 2,2-diphenyl-1-picryl-hydrazyl (DPPH; ) radicals with an IC
50 value of 316.21 μg/ml. It also decreases the cytopathic effects of parainfluenza type 3 virus with an IC
50 value of 11.7 μg/ml and a cytotoxic concentration (CC
50) value of 375 μg/ml in Hep-2 cells. Orientin (5-40 μM) inhibits LPS-induced barrier disruption, decreases the expression of toll-like receptor 4 (TLR4), phosphorylated p38, and NF-κB, and decreases TNF-α production and IL-6 secretion in a dose-dependent manner in human umbilical vein endothelial cells (HUVECs). It also prolongs survival in a mouse model of LPS-induced lethal endotoxemia when administered at a dose of 36 μg/animal 12 hours after LPS administration.
Chemische Eigenschaften
Yellow powder
Verwenden
Orientin is a flavone, a chemical flavonoid compound. Orientin have been investigated for its anti-oxidant, antihypertensive and antihyperlipidemic effects.
Definition
ChEBI: A C-glycosyl compound that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 8.
ORIENTIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ORIENTIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 236)Lieferanten
28608-75-5()Verwandte Suche:
- 2-(3,4-Dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
- ORIDONIN (RG)
- 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-.beta.-D-glucopyranosyl-5,7-dihydroxy-
- Aids026706
- Aids-026706
- 8-Glucosylluteolin
- ORIENTIN
- ORIENTINE
- Orientin, froM PolygonuM orientale
- Orientin,Lutexin
- 2-(3,4-dihydroxyphenyl)-8-beta-d-glucopyranosyl-5,7-dihydroxy-4h-1-benzopyra
- 4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-beta-d-glucopyranosyl-5,7-dihy
- luteolin8-glucoside
- lutexin
- orientin(flavone)
- ORIENTIN(P)
- ORIENTIN(SH)
- ORIENTIN WITH HPLC
- 8-β-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone
- 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-(β-D-glucopyranosyl)-4H-1-benzopyran-4-one
- 2-(3,4-Dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
- Orientin, 98%, from Polygonum orientale L.
- Orientin, 98%, from Polygonum orientale
- 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-
- Luteolin 8-C-beta-D-Glucopyranoside
- 8-beta-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone
- ORIENTIN USP/EP/BP
- 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one
- OrientinQ: What is
Orientin Q: What is the CAS Number of
Orientin Q: What is the storage condition of
Orientin Q: What are the applications of
Orientin
- LUTEOLIN-8-C-GLUCOSIDE
- Luteolin 8-C-β-D-glucopyranoside
- Polygonin
- 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-b-D-glucopyranosyl-5,7-dihydroxy-
- 28608-75-5
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Aromatics, Glucuronides, Pharmaceuticals, Intermediates & Fine Chemicals
