α-Aminotoluol-4-sulfonamidmonoacetat
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- CAS-Nr.
- 13009-99-9
- Bezeichnung:
- α-Aminotoluol-4-sulfonamidmonoacetat
- Englisch Name:
- Mafenide acetate
- Synonyma:
- Mefamide;mafatate;MARFANIL;MAFENIDE;maphenideacetate;MAFENIDE ACETATE;Sulfamylon Acetate;Mafenidine Acetate;MAFENAMIDE ACETATE;Sulfamimeron acetate
- CBNumber:
- CB7750274
- Summenformel:
- C9H14N2O4S
- Molgewicht:
- 246.28
- MOL-Datei:
- 13009-99-9.mol
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α-Aminotoluol-4-sulfonamidmonoacetat Eigenschaften
- Schmelzpunkt:
- 151-152°C
- storage temp.
- Inert atmosphere,2-8°C
- Löslichkeit
- DMSO: soluble1mg/mL
- Aggregatzustand
- Solid
- Farbe
- white
- CAS Datenbank
- 13009-99-9(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| HazardClass |
IRRITANT |
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| HS Code |
2935904000 |
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| Toxizität |
LD50 in rats, mice (mg/kg): 2040, 1580 i.v. (Skulan, Hoppe) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H332 |
Gesundheitsschädlich bei Einatmen. |
Akute Toxizität inhalativ |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P271, P304+P340, P312 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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α-Aminotoluol-4-sulfonamidmonoacetat Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Crystalline Solid
Allgemeine Beschreibung
4-(Aminomethyl)benzenesulfonamide acetate (Sulfamylon)is a homologue of the sulfanilamide molecule. It is not atrue sulfanilamide-type compound, as it is not inhibited byPABA. Its antibacterial action involves a mechanism thatdiffers from that of true sulfanilamide-type compounds.
This compound is particularly effective against Clostridiumwelchii in topical application and was used duringWorld War II by the German army for prophylaxis ofwounds. It is not effective orally. It is currently used aloneor with antibiotics in the treatment of slow-healing, infectedwounds.
Some patients treated for burns with large quantities ofthis drug have developed metabolic acidosis. To overcomethis adverse effect, a series of new organic salts was prepared. The acetate in an ointment base proved to be themost efficacious.
α-Aminotoluol-4-sulfonamidmonoacetat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
α-Aminotoluol-4-sulfonamidmonoacetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 254)Lieferanten
13009-99-9(α-Aminotoluol-4-sulfonamidmonoacetat)Verwandte Suche:
- 4-aminomethylbenzenesulfonamide acetate salt
- 4-(aminomethyl)benzenesulfonamidemonoacetate
- 4-(aminomethyl)benzenesulfonimideacetate
- Mafenide Acetate (400 mg)
- Methotroxate Disodium
- α-AMINO-P-TOLUENSULFONAMIDEMONOACETATE
- A-AMINO-P-TOLUENSULFONAMIDEMONOACETATE
- Mefamide
- Sulfamylon Acetate
- α-Amino-p-toluenesulfonamide Acetate
- a-Amino-p-toluenesulfonamide Acetate
- Mafenide Acetate (200 mg)
- Mafenide acetate, >=99%
- 4-HOMOSULFANILAMIDE ACETATE
- 4-HOMOSULFANILAMIDE ACETATE SALT
- 4-(AMINOMETHYL)-BENZENESULFOAMIDE MONOACETATE
- 4-(AMINOMETHYL)BENZENESULFONAMIDE ACETATE
- ALPHA-AMINO-P-TOLUENSULFONAMIDE MONOACETATE
- P-(AMINOMETHYL) BENZENESULFONAMIDE ACETATE
- P-AMINOMETHYLBENZENESULFONAMIDE ACETATE SALT
- alpha-aminotoluene-4-sulphonamide monoacetate
- Mafenidine Acetate
- MAFENIDE ACETATE, 4-(AMINOMETHYL)-BENZENESULFOAMIDE MONOACETATE
- 4-(aminomethyl)-benzenesulfonamidmonoacetate
- alpha-amino-p-toluenesulfonamidmonoacetate
- mafatate
- maphenideacetate
- MARFANIL
- MARFANIL ACETATE SALT
- MAFENAMIDE ACETATE
- MAFENIDE
- MAFENIDE ACETATE
- MAFENIDE ACETATE SALT
- Benzenesulfonamide, 4-(aminomethyl)-, acetate (1:1)
- Mafenide acetate USP/EP/BP
- Mafenide Acetate (1373008)
- Sulfamimeron acetate
- 13009-99-9
- C7H10N2O2SC2H4O2
- C2H4O2C7H10N2O2S
- Analytical Standards
- AM to AQ
- Analytical Chromatography Product Catalog
- Alphabetic
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Sulfur & Selenium Compounds
- APIs
- bc0001
