GLYCOFUROL
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- CAS-Nr.
- 31692-85-0
- Englisch Name:
- GLYCOFUROL
- Synonyma:
- TETRAGLYCOL;THFP;GLYCOFUROL;TETRAGLYCO;Glycofural;Glycofurol75;Glycofurolum 75;GLYCOFUROL-SPECIAL;GLYCOFUROL TETRAGLYCOL;Tetraglycol ( Glycofurol)
- CBNumber:
- CB7756948
- Summenformel:
- C11H21O5R
- Molgewicht:
- 233.28
- MOL-Datei:
- 31692-85-0.mol
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GLYCOFUROL Eigenschaften
- Siedepunkt:
- 100-145 °C0.4 mm Hg
- Dichte
- 1.09 g/mL at 25 °C(lit.)
- Dampfdruck
- 4.97-37.4Pa at 20-50℃
- Brechungsindex
- n20/D 1.462(lit.)
- Flammpunkt:
- >230 °F
- storage temp.
- Store below +30°C.
- Löslichkeit
- Chloroform (Sparingly), Methanol (Slightly, Sonicated)
- Aggregatzustand
- Oil
- Farbe
- Colourless
- Stabilität:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- LogP
- -1.21--0.38
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| RTECS-Nr. |
MD0907500 |
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| HS Code |
3907 20 20 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
| P337+P313 |
Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
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GLYCOFUROL Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Glycofurol is a clear, colorless, almost odorless liquid, with a bitter
taste; it produces a warm sensation on the tongue.
Verwenden
Glycofurol is used as a carrier device for drug delivery.
Vorbereitung Methode
Glycofurol is prepared by the reaction of tetrahydrofurfuryl alcohol
with ethylene oxide (followed by a special purification process in
the case of Glycofurol 75).
Pharmazeutische Anwendungen
Glycofurol is used as a solvent in parenteral products for
intravenous or intramuscular injection in concentrations up to
50% v/v. It has also been investigated, mainly in animal studies,
for use as a penetration enhancer and solvent in topical and
intranasal formulations. Glycofurol has also been used at 20%
v/v concentration in a rectal formulation.
Sicherheit(Safety)
Glycofurol is mainly used as a solvent in parenteral pharmaceutical
formulations and is generally regarded as a relatively nontoxic and
nonirritant material at the levels used as a pharmaceutical excipient.
Glycofurol can be irritant when used undiluted; its tolerability is
approximately the same as propylene glycol.
Glycofurol may have an effect on liver function and may have a
low potential for interaction with hepatoxins or those materials
undergong extensive hepatic metabolism.
LD50 (mouse, IV): 3.5 mL/kg
Lager
Stable if stored under nitrogen in a well-closed container protected
from light, in a cool, dry place.
Inkompatibilitäten
Incompatible with oxidizing agents.
Regulatory Status
Included in parenteral medicines licensed in Europe.
GLYCOFUROL Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
GLYCOFUROL Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 98)Lieferanten
31692-85-0()Verwandte Suche:
- Glycols,polyethylene,mono(tetrahydrofurfuryl)ether
- tetrahydrofurfurylalkoholpolyaethylenglycolaether
- Tetraglycol,Glycofurol, Tetrahydrofurfuryl alcohol polyethyleneglycol ether
- POLY(ETHYLENE GLYCOL) TETRAHYDROFURFURYL ETHER
- TETRAHYDROFURFURYL POLYETHYLENE GLYCOL 200
- TETRAHYDROFURFURYL ALCOHOL POLYETHYLENEGLYCOL ETHER
- Tetrahydrofurfuryl polyethylene glycol ether
- GLYCOFUROL
- GLYCOFUROL TETRAGLYCOL
- TETRAGLYCO
- Tetraglycol ( Glycofurol)
- TetrahydrofurfurylAlcoholPEGether
- Poly(oxy-1,2-ethanediyl), .alpha.-(tetrahydro-2-furanyl)methyl-.omega.-hydroxy-
- mixture of diethylene and triethylene glycol mono-tetrahydrofurfuryl ether
- 2-ethanediyl),alpha-[(tetrahydro-2-furanyl)methyl]-omega-hydroxy-Poly(oxy-1
- alpha-((tetrahydro-2-furanyl)methyl)-omega-hydroxy-poly(oxy-2-ethanediyl)
- Glycofurol75
- GLYCOFUROL-SPECIAL
- 2-(oxolan-2-ylmethoxy)ethanol
- Glycofurol, Tetrahydrofurfuryl alcohol polyethyleneglycol ether
- Tetrahydrofurfuryl polyethylene glycol 200, Mixture of diethylene and triethylene glycol mono-tetrahydrofurfuryl ether
- alpha-((Tetrahydro-2-furanyl)methyl)-omega-hydroxy-poly(oxy-1,2-E- thanediyl)
- Ethylene oxide homopolymer 2-tetrahydrofuranylmethyl ether
- Glycofural
- Glycofurolum 75
- TETRAHYDROFURFURYL ALCOHOL POLYETHYLENE
- GLYCOFUROL ISO 9001：2015 REACH
- Poly(oxy-1,2-ethanediyl),a-[(tetrahydro-2-furanyl)methyl]-w-hydroxy-
- Glycofurol extrapure, 99%
- THFP
- TETRAGLYCOL
- 31692-85-0
- C2H4OnC5H10O2
- HOCH2CH2O4H
- Biochemicals and Reagents
- BioChemical
- Carbohydrates
- Monosaccharide
- Heterobifunctional PEGs
- Materials Science
- Poly(ethylene glycol) and Poly(ethylene oxide)
- Polymer Science
- Polymers
