Allylbromid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R11:Leichtentzündlich.
R23/25:Giftig beim Einatmen und Verschlucken.
R34:Verursacht Verätzungen.
R50:Sehr giftig für Wasserorganismen.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Aussehen Eigenschaften
C3H5Br; Allylbromid. Farblose Flüssigkeit mit stechendem Geruch.
Gefahren für Mensch und Umwelt
Giftig beim Verschlucken. Reizt die Atmungsorgane, Augen und die Haut.
Schädigt Herz, Kreislauf, Leber und Nieren. Inhalation kann zu Bewusstlosigkeit führen.
Nicht stark erhitzen.
Nicht mit Alkalimetallen, Erdalkalimetallen, Leichtmetallen und Amiden in Berührung bringen.
Leichtentzündlich.
Schutzmaßnahmen und Verhaltensregeln
Geeignete Schutzhandschuhe als kurzzeitiger Spritzschutz.
Verhalten im Gefahrfall
Mit flüssigkeitsbindendem Material aufnehmen. Der Entsorgung zuführen. Nachreinigen.
Kohlendioxid, Wasser.
Brennbar. Dämpfe schwerer als Luft. Mit Luft Bildung explosionsfähiger Gemische. Im Brandfall kann Bromwasserstoff freigesetzt werden.
Erste Hilfe
Nach Hautkontakt: Mit reichlich Wasser abwaschen. Abtupfen mit Polyethylenglycol 400.
Nach Augenkontakt: Bei geöffnetem Lidspalt mit reichlich fliessendem Wasser (Augendusche!) mindestens 15 Minuten ausspülen. Sofort Augenarzt hinzuziehen.
Nach Einatmen: Frischluft. Arzt hinzuziehen.
Nach Verschlucken: Reichlich Wasser trinken. Erbrechen auslösen. Sofort Arzt hinzuziehen.
Nach Kleidungskontakt: Kontaminierte Kleidung sofort entfernen.
Ersthelfer: siehe gesonderten Anschlag
Sachgerechte Entsorgung
Als halogenhaltige, organische Lösemittelabfälle.
Chemische Eigenschaften
Allyl bromide is a clear to light yellow liquid. As an alkylating agent, allyl bromide is used
extensively in the synthesis of polymers, pharmaceuticals, allyls, and other organic compounds.
Allyl bromide is a clear liquid with an intense, acrid, persistent smell and is flammable.
It is insoluble in water, but soluble in alcohol, aether, acetone, carbon tetrachloride,
and chloroform. In fact, allyl bromide is used in the synthesis of other allyl compounds, to
synthesize dyestuff, spice, and as a curative in the medicine industry. Allyl bromide has a
very high mobility in soil. It is also used as a soil fumigant and as a contact poison. Allyl
bromide induces unscheduled DNA synthesis in HeLa cells.
Verwenden
Allyl Bromide is used as a reagent in the synthesis of Resveratrol derivatives. Resveratrol (R150000) is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet a
ggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion a
nd progression.
Allgemeine Beschreibung
A clear colorless to light yellow liquid with an irritating unpleasant odor. Flash point 30°F. Irritates eyes, skin, and respiratory system. Toxic by skin absorption. Denser than water and slightly soluble in water.
Air & Water Reaktionen
Highly flammable. Slightly soluble in water.
Reaktivität anzeigen
Allyl bromide decomposes upon heating and exposure to light, forming HBr (a strong reducing agent). Reacts violently with oxidizing agents. Can react exothermically with reducing agents to release hydrogen gas. In the presence of various catalysts (such as acids) or initiators, may undergo exothermic addition polymerization reactions.
Hazard
Strong irritant to skin and eyes, flammable,
high fire risk. Upper respiratory tract irritant. Ques-
tionable carcinogen.
Health Hazard
Exposures to allyl bromide cause severe eye and skin burns, irritation to the eyes, skin,
and respiratory system. It is harmful when absorbed through the skin or inhaled in the
workplace. Laboratory rats exposed for a prolonged period of time developed symptoms
of poisoning, such as excessive salivation in a small number of animals, and severe gastric
irritation. Vapors of allyl bromide may cause dizziness or suffocation, headache, coughing,
and distressed breathing.
Sicherheitsprofil
Poison by ingestion and intraperitoneal routes. Mdly toxic by inhalation. Human mutation data reported. See also ALLYL CHLORIDE and ALLYL COMPOUNDS. Dangerous fire and explosion hazard when exposed to heat, flame, or oxidizers. When heated to decomposition it emits toxic fumes of Br-. To fight fire, use alcohol foam, water spray or mist, CO2, dry chemical
Synthese
Allyl alcohol was synthesized from glycerol and formic acid under inert atmosphere, hydrolysed with NaOH and fractionally distilled to yield the 73% allyl alcohol water azeotrope. This was then reacted with 48% hydrobromic acid and sulfuric acid and the allyl bromide distilled as per the conventional method. It was then redistilled with 3A molecular sieves drying agent to yield the final product which is stored over additional 3A molecular sieves.
mögliche Exposition
Used as an insecticide; in the manufacture of resins, fragrances, and other chemicals
Lager
Allyl bromide should be stored separate from oxidizing materials and alkalis in a cool,
dry, well-ventilated location in tightly closed containers.
Versand/Shipping
UN1099 Allyl bromide, Hazard Class: 3; Labels: 3-Flammable liquid, 6.1-Poisonous materials
läuterung methode
Wash the bromide with NaHCO3 solution then distilled water, dry (CaCl2 or MgSO4), and fractionally distil. Protect it from strong light. [Beilstein 1 IV 754.] LACHRYMATORY, HIGHLY TOXIC and FLAMMABLE.
Inkompatibilitäten
Vapor may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Heat or light exposure may cause decomposition and corrosive vapors.
Waste disposal
In accordance with 40CFR 165 recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.
Vorsichtsmaßnahmen
Workers should wear positive pressure self-contained breathing apparatus (SCBA), goggles
and a face shield, protective clothing for high concentrations of vapor, chemical protective
clothing that is specifi cally recommended by the manufacturer to avoid poisoning.
Workers should be careful as allyl bromide reacts with oxidizing materials and alkalis.
Allylbromid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
