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Sodium thiosulfate pentahydrate Produkt Beschreibung

Sodium thiosulfate pentahydrate Struktur
10102-17-7
CAS-Nr.
10102-17-7
Englisch Name:
Sodium thiosulfate pentahydrate
Synonyma:
16g;17g;18g;23g;26g;27g;1kg;HYPO;FPV9;4-MPH
CBNumber:
CB8108182
Summenformel:
H10Na2O8S2
Molgewicht:
248.18
MOL-Datei:
10102-17-7.mol

Sodium thiosulfate pentahydrate Eigenschaften

Schmelzpunkt:
48.5 °C
Siedepunkt:
100 C
Dichte
1.01 g/mL at 25 °C
storage temp. 
Store at RT.
Löslichkeit
H2O: 1 M at 20 °C, clear, colorless
Aggregatzustand
Solid
Farbe
White tranparent
Wichte
1.729
PH
6.0-7.5 (100g/l, H2O, 20℃)
Wasserlöslichkeit
680 g/L (20 ºC)
Merck 
14,8694
Stabilität:
Stable. Incompatible with strong acids, iodine, mercury.
InChIKey
AKHNMLFCWUSKQB-UHFFFAOYSA-L
CAS Datenbank
10102-17-7(CAS DataBase Reference)
EPA chemische Informationen
Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate(10102-17-7)

Sicherheit

Kennzeichnung gefährlicher Xi
R-Sätze: 36/37/38
S-Sätze: 24/25-37/39-36-26
WGK Germany  1
RTECS-Nr. WE6660000
10
TSCA  Yes
HS Code  28323000
Toxizität LD50 orally in Rabbit: > 5000 mg/kg

Sodium thiosulfate pentahydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Chemische Eigenschaften

translucent crystals or white powder

Chemische Eigenschaften

Sodium thiosulfate occurs as odorless and colorless crystals, a crystalline powder or granules. It is efflorescent in dry air and deliquescent in moist air.

Verwenden

Titrimetry.

Vorbereitung Methode

On an industrial scale, sodium thiosulfate is produced chiefly from liquid waste products of sodium sulfide or sulfur dye manufacture. Small-scale synthesis is done by boiling an aqueous solution of sodium sulfite with sulfur.

Trademarks

Sulfactol (Sterling Winthrop).

Pharmazeutische Anwendungen

Sodium thiosulfate is used as an antioxidant in pharmaceuticals (ophthalmic, intravenous, and oral preparations). It has also been used for its antifungal properties and as a reagent in analytical chemistry.

Sicherheit(Safety)

Sodium thiosulfate is used in ophthalmic, intravenous, and oral pharmaceutical preparations. Apart from osmotic disturbances, sodium thiosulfate is relatively nontoxic. It is moderately toxic by the subcutaneous route and mildly irritating to respiratory tract and skin. Large oral doses have a cathartic action.
LD50 (IP, mouse) 5.6 g/kg
LD50 (IV, mouse) 2.4 g/kg

Lager

Sodium thiosulfate decomposes on heating. The bulk powder should be stored in a cool place, and the container should be kept tightly closed in a dry and well-ventilated place. It should not be stored near acids.

läuterung methode

Crystallise it from EtOH/H2O solutions or from water (0.3mL/g) below 60o by cooling to 0o, and dry it at 35o over P2O5 under vacuum. [Foerster & Mommsen Chem Ber 57 258 1924.] This salt is used as a secondary standard in volumetric analysis [Kilpatrick J Am Chem Soc 45 2132 1923], and is used as “Hypo” in photography [Hargreaves & Dunningham J Soc Chem Ind 42 147T 1923.]

Inkompatibilitäten

Sodium thiosulfate is incompatible with iodine, with acids, and with lead, mercury, and silver salts. It may reduce the activity of some preservatives, including bronopol, phenylmercuric salts, and thimerosal.

Regulatory Status

GRAS listed. Included in the FDA Inactive Ingredients Database (IV solutions; ophthalmic solutions and suspensions; oral capsules, solutions, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Sodium thiosulfate pentahydrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Sodium thiosulfate pentahydrate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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