ANTI-DPC4

ANTI-DPC4 Struktur
CAS-Nr.
Englisch Name:
ANTI-DPC4
Synonyma:
Anti-JIP;ANTI-DPC4;ANTI-SMAD4;Anti-MADH4;Anti-hSMAD4;ANTI-HUMAN DPC4;ANTI-HUMAN SMAD4;ANTI-SMAD4(H-552);ANTI-SMAD4 (DPC4);Anti-MAD homolog 4
CBNumber:
CB8123284
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-DPC4 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous glycerol solution

Sicherheit

WGK Germany  3

ANTI-DPC4 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-SMAD4 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

Allgemeine Beschreibung

The gene SMAD4 (mothers against decapentaplegic homolog 4) is mapped to human chromosome 18q21.1. The protein localizes in the cytoplasm and nucleus. SMAD4 is also referred as DPC4 (deleted in pancreatic carcinoma).

Biochem/physiol Actions

Upon TGFβ (transforming growth factor β) activation, SMAD (mothers against decapentaplegic homolog) proteins are responsible for transcription activation in the nucleus. SMAD4 is a crucial protein of TGFβ signaling. It promotes association of SMAD2/4 to DNA and helps SMAD1/2 in transcription stimulation. Mutations in SMAD4 are linked with juvenile polyposis syndrome, hereditary haemorrhagic telangiectasia and Myhre syndrome. In renal cell carcinoma, it activates forkhead box protein H1 and thereby inhibits the progression of the carcinoma. SMAD4 is considered as a tumor suppressor protein.

ANTI-DPC4 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-DPC4 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 25)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai guandao biology engineering co., ltd 18818239863 18818239863
3171921642@qq.com China 8884 58

  • Anti-Mothers against decapentaplegic homolog 4
  • Anti-Mothers against DPP homolog 4
  • Anti-SMAD4 antibody produced in rabbit
  • DPC4/SMAD4 (AB-1) MONOCLONAL ANTIBODY
  • ANTI-SMAD4
  • ANTI-SMAD4 (DPC4)
  • ANTI-SMAD4(H-552)
  • ANTI-HUMAN DPC4
  • ANTI-HUMAN SMAD4
  • ANTI-DELETED IN PANCREATIC CANCER LOCUS 4 PROTEIN
  • ANTI-DPC4
  • ANTI-DPC4/SMAD4, HUMAN
  • ANTI-DPC4/SMAD4 MOUSE MAB
  • Anti-Deleted in pancreatic carcinoma locus 4
  • Monoclonal Anti-Smad4 (DPC4) antibody produced in mouse
  • Anti-JIP
  • Anti-MAD homolog 4
  • Anti-MADH4
  • Anti-SMAD family member 4
  • Anti-SMAD, mothers against DPP homolog 4 (Drosophila)
  • Anti-Deletion target in pancreatic carcinoma 4
  • Anti-hSMAD4
  • Alphabetical Index
  • Antibodies for Gene Regulation and Expression
  • Antibodies to Transcription FactorsAntibodies
  • Cell Biology
  • Clone Index
  • DAntibodies
  • SM-SZ
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