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IBERIOTOXIN

IBERIOTOXIN Struktur
129203-60-7
CAS-Nr.
129203-60-7
Englisch Name:
IBERIOTOXIN
Synonyma:
IBTX;RLBTX;IBERIOTOXIN;IBERIOTOXIN 98%;Iberiotoxin Standard;IBERIOTOXIN USP/EP/BP;IBERIOTOXIN, RECOMBINANT;IBERIOTOXIN, BUTHUS TAMULUS;129203-60-7/182897-30-9（TFA);M.W. 4230.91 C179H274N50O55S7
CBNumber:
CB8130448
Summenformel:
C179H274N50O55S7
Molgewicht:
4230.84786
MOL-Datei:
129203-60-7.mol
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IBERIOTOXIN Eigenschaften

storage temp. 
-20°C
Löslichkeit
H2O: 1 mg/mL, clear, colorless
Aggregatzustand
Salt-free lyophilized solid
Wasserlöslichkeit
Soluble to 0.70 mg/ml in water

Sicherheit

Kennzeichnung gefährlicher T+
R-Sätze: 26/27/28
S-Sätze: 28-36/37-45
RIDADR  UN 3462 6.1/PG 2
WGK Germany  3
RTECS-Nr. NH6107500
F  3-10

IBERIOTOXIN Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).

Verwenden

Iberiotoxin is a selective and reversible inhibitor of high-conductance calcium-activated potassium channel. A toxin purified from the Eastern Indian red scorpion Buthus tamulus.

Biochem/physiol Actions

The single chain peptide iberiotoxin (IbTX) is a selective and reversible inhibitor of high-conductance calcium-activated potassium channels (PK,Ca). It occurs naturally in the venom of the scorpion Buthus tamulus. IbTX also modulates the binding of charybdotoxin (CbTX) to smooth muscle sarcolemmal membranes in a non-competitive manner. IbTX is similar in size to CbTX and shares considerable sequence homology with CbTX. However, IbTX differs in its overall charge in having one fewer basic and four more acidic residues than CbTX.

IBERIOTOXIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

IBERIOTOXIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 79)Lieferanten
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Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 57511 58
Hefei KS-V Peptide Biotechnology Co., Ltd. 0551-65120828 17368858770
 sales1@difficultpeptide.com China 118 58

129203-60-7()Verwandte Suche:

Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')europium Aluminiumtris(2,4-pentandionato-O,O') N-Butylisocyanid Ethylisocyanacetat (Ethylenbis(nitrilomethylidyn)-2,2'-diphenolato)cobalt(II) (Pentan-2,4-dionato-O,O')silber Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')dysprosium Benzylisocyanid 2-Methylpropylisocyanid 1,1,3,3-Tetramethylbutylisocyanat (p-Toluolsulfonyl)methylisocyanid Phenylselenol Methylisocyanacetat Dichloro(ethylendiamin)platin Kupfer(II)-4-oxopent-2-en-2-olat Tris(pentan-2,4-dionato)eisen(II)
  • PYR-PHE-THR-ASP-VAL-ASP-CYS-SER-VAL-SER-LYS-GLU-CYS-TRP-SER-VAL-CYS-LYS-ASP-LEU-PHE-GLY-VAL-ASP-ARG-GLY-LYS-CYS-MET-GLY-LYS-LYS-CYS-ARG-CYS-TYR-GLN
  • iberiotoxin from buthus tamulus
  • IBERIOTOXIN, RECOMBINANT
  • IBERIOTOXIN 98%
  • PYR-PHE-THR-ASP-VAL-ASP-CYS-SER-VAL-SER-LYS-GLU-CYS-TRP-SER-VAL-CYS-LYS-ASP-LEU-PHE-GLY-VAL-ASP-ARG-GLY-LYS-CYS-MET-GLY-LYS-LYS-CYS-ARG-CYS-TYR-GLN-OH
  • PYR-PHE-THR-ASP-VAL-ASP-CYS-SER-VAL-SER-LYS-GLU-CYS-TRP-SER-VAL-CYS-LYS-ASP-LEU-PHE-GLY-VAL-ASP-ARG-GLY-LYS-CYS-MET-GLY-LYS-LYS-CYS-ARG-CYS-TYR-GLN-OH (DISULFIDE BRIDGE: C7-C28,C13-C33,C17-C35)
  • M.W. 4230.91 C179H274N50O55S7
  • pGlu-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln-OH
  • Iberiotoxin, recombinant from Mesobuthus tamulus
  • IBERIOTOXIN FROM BUTHUS TAMULUS, 50 UG*
  • IBTX
  • IBTX (SCORPION, BUTHUS TAMULUS)
  • IBERIOTOXIN
  • IBERIOTOXIN, BUTHUS TAMULUS
  • IBERIOTOXIN SCORPION BUTHUS TAMULUS
  • PGLU-PHE-THR-ASP-VAL-ASP-CYS-SER-VAL-SER-LYS-GLU-CYS-TRP-SER-VAL-CYS-LYS-ASP-LEU-PHE-GLY-VAL-ASP-ARG-GLY-LYS-CYS-MET-GLY-LYS-LYS-CYS-ARG-CYS-TYR-GLN [DISULFIDE BRIDGES: 7-28, 13-3, 17-3]
  • RLBTX
  • PYR-FTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ
  • PYR-FTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ(DISULFIDE BRIDGE: C7-C28,C13-C33,C17-C35)
  • Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem
  • IBERIOTOXIN USP/EP/BP
  • Iberiotoxin Standard
  • 129203-60-7/182897-30-9（TFA)
  • 129203-60-7
  • C179H274N50O55S7
  • C179H273N49O56S7
  • Voltage-gated Ion Channels
  • Potassium Channel Modulators
  • Other
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Type
  • Monovalent Ion Channels
  • Ion Channels
  • BioChemical
  • Biochemicals and Reagents
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Type
  • Other
  • Potassium channel
  • Ion Channel Modulating Peptides
  • Potassium Channel ModulatorsPeptides for Cell Biology
  • Monovalent Ion Channels
  • Potassium Channel ModulatorsCell Signaling and Neuroscience
  • Scorpion
  • Toxins and Venoms
  • Voltage-gated Ion Channels
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