lactosyl lysosphingolipid

lactosyl lysosphingolipid Struktur
109785-20-8
CAS-Nr.
109785-20-8
Englisch Name:
lactosyl lysosphingolipid
Synonyma:
Lactosyl-C18-sphingosine;lactosyl lysosphingolipid;lactosyl-beta-sphingosine;Lactosylsphingosine (d18:1);Lactosyl(ss) Sphingosine (d18:1);Lyso-Lactosylceramide (synthetic);Lactosyl(beta) Sphingosine (d18:1);D-lactosyl-1-1'-D-erythro-sphingosine;D-lactosyl-?1-1'-D-erythro-sphingosine;Lactosylsphingosine (d18:1) (synthetic)
CBNumber:
CB81329335
Summenformel:
C30H57NO12
Molgewicht:
623.77308
MOL-Datei:
109785-20-8.mol

lactosyl lysosphingolipid Eigenschaften

Siedepunkt:
845.8±65.0 °C(Predicted)
Dichte
1.27±0.1 g/cm3(Predicted)
storage temp. 
-20°C
Löslichkeit
Chloroform:Methanol:Water (2:1:0.1): soluble; DMSO: soluble; Water: soluble
Aggregatzustand
A solid
pka
11.74±0.45(Predicted)
BRN 
5680460

Sicherheit

lactosyl lysosphingolipid Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosylsphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosylsphingosine is a precursor in the synthesis of lyso-ganglioside GM3. [Matreya, LLC. Catalog No. 2088]

Verwenden

Lactosyl(β) Sphingosine (d18:1) or D-lactosyl-β1-1′-D-erythro-sphingosine has been used as an internal standard for the quantification of psychosine?using tandem mass spectrometry. It may be used to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial?tissue. It may also be used as a standard to determine the extent of recovery of lyso-neutral glycosphingolipids (lyso-n-GSLs) from the Sephadex column.

Allgemeine Beschreibung

Lactosyl sphingosine?is a glycosylsphingosine (Lyso-GSL), which is found in bovine brain white matter extract.

lactosyl lysosphingolipid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


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  • lactosyl lysosphingolipid
  • D-lactosyl-1-1'-D-erythro-sphingosine
  • 2-[6-[(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enoxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
  • Lactosylsphingosine (d18:1)
  • Lyso-Lactosylceramide (synthetic)
  • Lactosyl-C18-sphingosine
  • Lactosylsphingosine (d18:1) (synthetic)
  • Lactosyl(ss) Sphingosine (d18:1)
  • Lactosyl(beta) Sphingosine (d18:1)
  • β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl 4-O-β-D-galactopyranosyl-
  • Lacsph d18:1 (Galb1,4GlcbSphingolipids)
  • lactosyl-beta-sphingosine
  • D-lactosyl-?1-1'-D-erythro-sphingosine
  • 109785-20-8
  • C30H57NO12
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