Ethyl (R)-3-hydroxybutyrate
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- CAS-Nr.
- 24915-95-5
- Englisch Name:
- Ethyl (R)-3-hydroxybutyrate
- Synonyma:
- grape butyrate;(R)-grape butyrate;2-ethyl-3-hydroxybutanoate;ETHYL (R)-3-HYDROXYBUTYRATE;ETHYL (R)-3-HYDROXYBUTYLATE;ethyl (3R)-3-hydroxybutanoate;ETHYL R-(-)-3-HYDROXYBUTANOATE;(R)-(-)-Ethyl 3-Hydrobutyrate;Ethyl (R)-3-hydroxybutyrate,98%;ETHYL (R)-(-)-3-HYDROXYBUTYRATE
- CBNumber:
- CB8214494
- Summenformel:
- C6H12O3
- Molgewicht:
- 132.16
- MOL-Datei:
- 24915-95-5.mol
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Ethyl (R)-3-hydroxybutyrate Eigenschaften
- alpha
- -45.5 º (589nm, c=1, CHCl3)
- Siedepunkt:
- 75-76 °C/12 mmHg (lit.)
- Dichte
- 1.017 g/mL at 25 °C (lit.)
- Dampfdruck
- 17.2Pa at 20℃
- Brechungsindex
- n20/D 1.42(lit.)
- Flammpunkt:
- 148 °F
- storage temp.
- 2-8°C
- Aggregatzustand
- Liquid
- pka
- 14.45±0.20(Predicted)
- Wichte
- 1.017
- Farbe
- Clear, Colorless
- Optische Aktivität
- [α]20/D 46°, c = 1 in chloroform
- Wasserlöslichkeit
- soluble
- LogP
- 0.341 at 20℃
- CAS Datenbank
- 24915-95-5(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H227 |
Combustible liquid |
Flammable liquids |
Category 4 |
Warnung |
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P210, P280, P370+P378, P403+P235,P501 |
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| Sicherheit |
| P210 |
Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P403+P235 |
An einem gut belüfteten Ort aufbewahren. Kühl halten. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Ethyl (R)-3-hydroxybutyrate Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Ethyl (R)-(-)-3-Hydroxybutyrate is a chiral starting material for the production of numerous biologically active compounds.
Chemische Eigenschaften
clear colorless liquid
Verwenden
Ethyl (R)-(-)-3-hydroxybutyrate is a chiral building block for the preparation of bioactive compounds used in the pharmaceutical industry. It is formed during the hydrolysis of poly-3-hydroxybutyrate.
Allgemeine Beschreibung
Ethyl (R)-3-hydroxybutyrate is an enantiomer of
3-hydroxybutyric acid. It is synthesized from diethyl succinate in a
one-pot, stereoselective, high-yield process by using asymmetric
synthesis and hydrogenation. The reaction vessel used for this synthesis
is a reaction solution that has been optimized to be resistant to high
pressure and temperature. This product can be used as a renewable
feedstock in the production of polyesters and other polymers.
Synthese
(R)-β-Butryrolactone (20 g, 230 mmol) was dissolved in 500 mLethanol with 1.0 mL H2SO4 and stirred at room temperature. Aliquots(100 μL) were added to 1.0 mL of methanol and analyzed by GC-MS for conversion of the lactone. Upon completion (> 48 h), a small amount of solid sodium bicarbonate was added and the solvent removed by rotary evaporation. The residue was taken up in dichloromethane and washed with water. The water layer was extracted twice with ethyl acetate. The pooled organic layers were dried with magnesium sulfate, which was then filtered and the solvent removed by rotary evaporation to yield Ethyl (R)-3-hydroxybutyrate as a clear oil (20.2 g, 66%).
Ethyl (R)-3-hydroxybutyrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Ethyl (R)-3-hydroxybutyrate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 269)Lieferanten
24915-95-5()Verwandte Suche:
- (R)-(-)-ETHYL 3-HYDROXYBUTANOATE
- (R)-(-)-ETHYL 3-HYDROXYBUTYRATE
- (R)-(-)-3-HYDROXYBUTYRIC ACID ETHYL ESTER
- (R)-3-HYDROXYBUTYRIC ACID ETHYL ESTER
- (R)-(-)-3-HYDROXY-N-BUTYRIC ACID ETHYL ESTER
- ENZYME MEMBRANE REACTOR (WITHOUT SUPPLEMENTARY ACCESSORIES) EE 99+%
- ETHYL R-(-)-3-HYDROXYBUTANOATE
- ETHYL (R)-(-)-3-HYDROXYBUTYRATE
- ETHYL (R)-3-HYDROXYBUTYRATE
- ETHYL (R)-3-HYDROXYBUTANOATE R-3-HYDROXYBUTYRIC ACID ETHYL ESTER
- Ethyl (R)-3-hydroxybutyrate,98%
- (R)-(-)-Ethyl 3-Hydrobutyrate
- ETHYL (R)-3-HYDROXYBUTYLATE
- Ethyl (R)-3-hydroxybutyrate, 98% 5GR
- Butanoic acid,3-hydroxy-, ethyl ester, (3R)-
- Ethyl (R)-(-)-3-hydroxybutyrate 98%
- grape butyrate
- ethyl (3R)-3-hydroxybutanoate
- 2-ethyl-3-hydroxybutanoate
- Ethyl(R)-(-)-3-Hydroxybutyrate>
- Ethyl (R)-3-hydroxybutyrate Basic information
- (R)-grape butyrate
- 24915-95-5
- 24915-95-5
- 24915-95-9
- C6H12O3
- CH3CHOHCH2CO2C2H5
- Asymmetric Synthesis
- Simple Alcohols (Chiral)
- Chiral Building Blocks
- Esters
- Organic Building Blocks
- Chiral Alcohols
- Alcohols, Hydroxy Esters and Derivatives
- Chiral Compounds
- Chiral Building Blocks
- Simple Alcohols (Chiral)
- Synthetic Organic Chemistry
- Chiral Building Blocks
- Esters
- Organic Building Blocks
