Y27632 (hydrochloride)

Y27632 (hydrochloride) Struktur
129830-38-2
CAS-Nr.
129830-38-2
Englisch Name:
Y27632 (hydrochloride)
Synonyma:
CS-1919;Y27632 HCl;27632 (hydrochloride);Y27632 (hydrochloride);Y-27632; Y27632; Y 27632;Y-27632 dihydrochloride, >=98%;Y-27632 dihydrochloride Y27632;Y27632 (hydrochloride) USP/EP/BP;Y-27632, Dihydrochloride Salt, >99%;Y-27632 DIHYDROCHLORIDE;ROCK INHIBITOR
CBNumber:
CB82526054
Summenformel:
C14H23Cl2N3O
Molgewicht:
320.25792
MOL-Datei:
129830-38-2.mol

Y27632 (hydrochloride) Eigenschaften

Schmelzpunkt:
258℃
storage temp. 
2-8°C
Löslichkeit
H2O: soluble14mg/mL
Aggregatzustand
powder
Farbe
white to beige
Stabilität:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.

Sicherheit

Kennzeichnung gefährlicher Xn
R-Sätze: 20/21/22
S-Sätze: 36
WGK Germany  3
HS Code  29333990

Y27632 (hydrochloride) Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

A cell permeable inhibitor of ROCK-1 and ROCK-2

Allgemeine Beschreibung

Y-27632 dihydrochloride is an effective bronchodilator and improves lung resistance (RL) induced by antigen and acetylcholine. Y-27632 controls neutrophil migration and lung edema and may be a potential drug for treating acute lung injury.

Biochem/physiol Actions

Y-27632 is highly potent, cell-permeable, selective ROCK (Rho-associated coiled coil forming protein serine/threonine kinase) inhibitor. Ki = 140 nM for p160ROCK. Y-27632 also inhibits ROCK-II with equal potency. The inhibition is competitive with respect to ATP.

Y27632 (hydrochloride) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Y27632 (hydrochloride) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 158)Lieferanten
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Hangzhou FandaChem Co.,Ltd.
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18853181302
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sales@chemdad.com China 39916 58
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
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Dideu Industries Group Limited
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1026@dideu.com China 29321 58

  • (R)-4-(1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride
  • Y-27632 DIHYDROCHLORIDE;ROCK INHIBITOR
  • Y-27632 dihydrochloride, >=98%
  • trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride Y 27632 dihydrochloride
  • Y 27632 dihydrochloride (+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride
  • Y27632 (hydrochloride)
  • (+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride
  • trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
  • Y27632 HCl
  • Y-27632, Dihydrochloride Salt, >99%
  • Y-27632; Y27632; Y 27632
  • CS-1919
  • Y-27632; Y27632; Y 27632;Y 27632 DIHYDROCHLORIDE;Y27632 DIHYDROCHLORIDE
  • Y-27632 dihydrochloride, 98.5%, a selective ROCK1 (p160ROCK) inhibitor
  • trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride
  • Y27632 (hydrochloride) USP/EP/BP
  • Trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride (Y-27632 dihydrochloride)
  • Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, hydrochloride (1:2), trans-
  • Y-27632 dihydrochloride Y27632
  • 27632 (hydrochloride)
  • 129830-38-2
  • Inhibitors
  • APIs
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