SB 290157 trifluoroacetate salt

1140525-25-2

CAS-Nr.: 1140525-25-2

Englisch Name:: SB 290157 trifluoroacetate salt

Synonyma:: SB290157 (trifluoroacetate);SB 290157 trifluoroacetate salt;SB 290157 - CAS 1140525-25-2 - Calbiochem;SB 290157 TRIFLUOROACETATE; SB-290157 TRIFLUOROACETATE;N2-(2-(2,2-diphenylethoxy)acetyl)-L-arginine, 2,2,2-trifluor;N2-(2-(2,2-diphenylethoxy)acetyl)-L-arginine (trifluoroacetate);(2S)-5-(diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoic acid;SB290157,SB-290157 trifluoroacetate,Inhibitor,inhibit,SB 290157,Complement System,SB-290157,SB290157 trifluoroacetate

CBNumber:: CB82537362

Summenformel:: C24H29F3N4O6

Molgewicht:: 526.51

MOL-Datei:: 1140525-25-2.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 59

SB 290157 trifluoroacetate salt Eigenschaften

Schmelzpunkt:: >43°C (dec.)

storage temp.: -20°C

Löslichkeit: Ethanol (Slightly, Sonicated), Methanol (Slightly), Water (Slightly)

Aggregatzustand: powder

Farbe: white to beige

Optische Aktivität: [α]/D +1.5 to +5°, c = 1.0 in DMSO

Stabilität:: Hygroscopic

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H302	Gesundheitsschädlich bei Verschlucken.	Akute Toxizität oral	Kategorie 4	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P270, P301+P312, P330, P501
H315	Verursacht Hautreizungen.	Hautreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P302+P352, P321,P332+P313, P362
H319	Verursacht schwere Augenreizung.	Schwere Augenreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P305+P351+P338,P337+P313P
H335	Kann die Atemwege reizen.	Spezifische Zielorgan-Toxizität (einmalige Exposition)	Kategorie 3 (Atemwegsreizung)	Warnung	src="/GHS07.jpg" width="20" height="20" />

Sicherheit

P261	Einatmen von Staub vermeiden.
P305+P351+P338	BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

SB 290157 trifluoroacetate salt Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

SB 290157 Trifluoroacetate Salt is a selective, high affinity, competitive antagonist of anaphylatoxin C3a receptor.

Allgemeine Beschreibung

A non-peptide with anti-inflammatory properties that acts as a selective, high affinity, competitive antagonist of the anaphylatoxin C3a receptor (C3aR; IC₅₀ = 200 nM). Does not antagonize C5aR or other chemotactic G-protein coupled receptors. Blocks C3a-induced internalization of C3aR in human neutrophils and C3a-induced Ca²⁺ mobilization in basophilic leukemia RBL-2H3 cells expressing murine, guinea pig, or human C3aR (IC₅₀ = 7, 12.5, and 27.7 nM, respectively). Also blocks C3a-mediated ATP release from guinea pig platelets (IC₅₀ = 30 nM).

Biochem/physiol Actions

Target IC50: 200 nM against the anaphylatoxin C3a receptor; 7, 12.5, and 27.7 nM, in blocking C3a-induced internalization of C3aR in human neutrophils and C3a-induced Ca2+ mobilization in basophilic leukemia RBL-2H3 cells expressing murine, guinea pig, or human C3aR

SB 290157 trifluoroacetate salt Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

SB 290157 trifluoroacetate salt Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 59)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Chembest Research Laboratories Limited	021-20908456	sales@BioChemBest.com	China	6011	61
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632	sales@reading-chemicals.com	China	15185	58

SB 290157 trifluoroacetate salt
SB290157 (trifluoroacetate)
SB 290157 TRIFLUOROACETATE; SB-290157 TRIFLUOROACETATE
SB 290157 - CAS 1140525-25-2 - Calbiochem
(2S)-5-(diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoic acid
N2-(2-(2,2-diphenylethoxy)acetyl)-L-arginine, 2,2,2-trifluor
N2-(2-(2,2-diphenylethoxy)acetyl)-L-arginine (trifluoroacetate)
SB290157,SB-290157 trifluoroacetate,Inhibitor,inhibit,SB 290157,Complement System,SB-290157,SB290157 trifluoroacetate
1140525-25-2
C22H28N4O4CF3COOH