PTEROIC ACID

PTEROIC ACID Struktur
119-24-4
CAS-Nr.
119-24-4
Englisch Name:
PTEROIC ACID
Synonyma:
4-(((2-AMino-4-oxo-3,4-dihydropteridin-6-yl)Methyl)aMino)benzoic acid;Pyrofolic acid;4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid;NSC 14972;PTEROIC ACID;Butterfly acid;Pteroic Acid (>Pteroic acid >=93%;Pteroic Acid (>85%);Folic acid iMpurity D
CBNumber:
CB8254618
Summenformel:
C14H12N6O3
Molgewicht:
312.28
MOL-Datei:
119-24-4.mol

PTEROIC ACID Eigenschaften

Schmelzpunkt:
>400℃
Siedepunkt:
610.0±65.0 °C(Predicted)
Dichte
1.69
storage temp. 
2-8°C
Löslichkeit
Aqueous Base (Slightly), DMSO (Slightly)
pka
4.65±0.10(Predicted)
Farbe
Light Yellow to Brown
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
WGK Germany  3
HS Code  2933599590
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P271 Nur im Freien oder in gut belüfteten Räumen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

PTEROIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Pteroic Acid is a constituent as well as a degradation product of Folid Acid (F680300) formed via anzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutama te synthetase.

Allgemeine Beschreibung

Folic Acid Impurity D is an impurity of the water-soluble B-vitamin, folic acid. Folic Acid is generally used in the treatment of certain types of anemia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Enzyminhibitor

This metabolite (FWfree-acid = 312.29 g/mol; CAS 119-24-4), also known as 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, is a structural component of folates. Pteroic acid is a growth factor for a number of Enterococci. Pteroic acid is a yellow powder that is slightly soluble in aqueous NaOH. The lmax values in 0.1 M NaOH are 255, 275, and 365 nm (e = 26300, 23400, and 8900 M–1cm–1, respectively). Target(s): arylamine N-acetyltransferase; dihydrofolate reductase; dihydrofolate synthetase, weakly inhibited; dihydropteroate synthase; glutamate carboxypeptidase; and xanthine oxidase.

läuterung methode

Crystallise it from dilute HCl. Dry it in vacuo. Hygroscopic IRRITANT. [Nair et al. J Org Chem 46 3152 1981, Beilstein 26 III/IV 3942.]

PTEROIC ACID Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


PTEROIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 261)Lieferanten
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Henan Tianfu Chemical Co.,Ltd.
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Nanjing Finetech Chemical Co., Ltd.
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+undefined-21-51877795
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sales@chemdad.com China 39916 58

119-24-4()Verwandte Suche:


  • 4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid
  • 4-[(2-azanyl-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid
  • 4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid
  • 4-[[(2-AMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoic Acid
  • NSC 14972
  • p-[(2-AMino-4-hydroxy-6-pteridylMethyl)aMino]benzoic Acid
  • Benzoic acid, 4-[[(2-aMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]aMino]-
  • Folic acid iMpurity D
  • Folic acid iMpurity D Pteroic acid
  • Pteroic Acid (>85%)
  • Pteroic acid >=93%
  • NSC 14972 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid
  • 4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)
  • PTEROIC ACID
  • p-((2-amino-4-hydroxypteridin-6-yl)methylamino)benzoic acid
  • PTEROIC ACID HYDRATE, 90%
  • Folic acid impurity DQ: What is Folic acid impurity D Q: What is the CAS Number of Folic acid impurity D Q: What is the storage condition of Folic acid impurity D Q: What are the applications of Folic acid impurity D
  • 4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid(119-24-4)
  • 4-[(2-amino-4-oxo-8H-pteridin-6-yl)methylamino]benzoic acid
  • Folic Acid Impurity 6(Folic Acid EP Impurity D)
  • Methotrexate EP Impurity D Desmethyl Impurity
  • Pteroic Acid (>
  • 4-[[(2-Amino-4-oxo-1,4-dihydropteri
  • Folic acid impurity D CRS
  • 4-(((2-amino-4-hydroxypteridin-6-yl)
  • Methotrexate EP Impurity D N-Desmethyl Impurity
  • Pteroic acid(Instant type)
  • Folic Acid Impurity 6
  • Folic acid EP Impurity D
  • Pteroic acid - min95%
  • 4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid
  • Pyrofolic acid
  • 4-(((2-AMino-4-oxo-3,4-dihydropteridin-6-yl)Methyl)aMino)benzoic acid
  • Butterfly acid
  • 4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoicaci
  • Pteroic acid (7CI, 8CI)
  • Folic Acid Hydrate EP Impurity D
  • 119-24-4
  • C14H12N6O3
  • Heterocyclic Building Blocks
  • Quinazolines
  • Building Blocks
  • Heterocycles
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Building Blocks
  • Heterocyclic Building Blocks
  • Quinazolines
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