Bleomycinamid, N1-[3-[(1-Phenylethyl)amino]propyl]-, (S)-, Sulfat (1:1) (Salz)

70384-29-1

CAS-Nr.: 70384-29-1

Bezeichnung:: Bleomycinamid, N1-[3-[(1-Phenylethyl)amino]propyl]-, (S)-, Sulfat (1:1) (Salz)

Englisch Name:: PEPLOMYCIN SULFATE

Synonyma:: Pepleo;NK 631;Nsc276382;PEPLOMYCIN SULFATE;Pepleomycin Sulfate;N1-[3-[[(1S)-1-phenylethyl]aMino]propyl]bleoMycinaMide;N1-[3-[[(1S)-1-phenylethyl]amino]propyl]bleomycinamide Sulfate;Bleomycinamide, N1-[3-[(1-phenylethyl)amino]propyl]-, (S)-, sulfate (1:1) (salt)

CBNumber:: CB8413187

Summenformel:: C61H90N18O25S3

Molgewicht:: 1571.67

MOL-Datei:: 70384-29-1.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 16

Bleomycinamid, N1-[3-[(1-Phenylethyl)amino]propyl]-, (S)-, Sulfat (1:1) (Salz) Eigenschaften

Schmelzpunkt:: 196-198°C

alpha: 25436 -2.0° (c = 1 in water)

Löslichkeit: DMSO, DMF, Methanol, Water

Aggregatzustand: Powder

pka: 2.9, 4.8, 7.4, 9.0(at 25℃)

Farbe: Pale Yellow Amorphous

Sicherheit

Toxizität	LD50 in male rats, mice (mg/kg): 234, 88 s.c.; 208, 85 i.p.; 245, 51 i.v. (Ito)

Bleomycinamid, N1-[3-[(1-Phenylethyl)amino]propyl]-, (S)-, Sulfat (1:1) (Salz) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Peplomycin was derived biosynthetically from Streptomyces verticillus, the bleomycinproducing organism, in the course of efforts to obtain bleomycin derivatives with high activity and low toxicity. This antibiotic was found by Nippon Kayaku Co. and the Institute of Microbial Chemistry, Japan, in 1974. Its anticancer effects appear earlier than those of bleomycin; consequently, the period of therapy is shortened. Peplomycin is also active against metastatic cancer of the lymph nodes and shows less pneumotoxicity than bleomycin.

Chemische Eigenschaften

Pale Yellow Amorphous Powder

Sicherheitsprofil

Poison by intraperitoneal, subcutaneous, and intravenous routes. Questionable carcinogen with experimental carcinogenic data. An eye irritant. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Bleomycinamid, N1-[3-[(1-Phenylethyl)amino]propyl]-, (S)-, Sulfat (1:1) (Salz) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Schwefelsure

Downstream Produkte

Bleomycinamid, N1-[3-[(1-Phenylethyl)amino]propyl]-, (S)-, Sulfat (1:1) (Salz) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 16)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55717	58

70384-29-1(Bleomycinamid, N1-[3-[(1-Phenylethyl)amino]propyl]-, (S)-, Sulfat (1:1) (Salz))Verwandte Suche:

Ribostamycinsulfat Peplomycin Bleomycinamid, N1-[3-[(1-Phenylethyl)amino]propyl]-, (S)-, Sulfat (1:1) (Salz)

PEPLOMYCIN SULFATE
Bleomycinamide, N1-[3-[(1-phenylethyl)amino]propyl]-, (S)-, sulfate (1:1) (salt)
N1-[3-[[(1S)-1-phenylethyl]amino]propyl]bleomycinamide Sulfate
NK 631
Pepleo
Pepleomycin Sulfate
Nsc276382
N1-[3-[[(1S)-1-phenylethyl]aMino]propyl]bleoMycinaMide
70384-29-1
C61H90N18O25S3
Intermediates & Fine Chemicals
Pharmaceuticals
Chiral Reagents