4-Aminobenzohydrazid
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- CAS-Nr.
- 5351-17-7
- Bezeichnung:
- 4-Aminobenzohydrazid
- Englisch Name:
- 4-Aminobenzohydrazide
- Synonyma:
- 4-POBN;4NPhCON2;aminostimil;WLN: ZNUYQR DZ;ambenhydrazide;Amben hydrazide;TIMTEC-BB SBB007555;P-AMINOBENZHYDRAZIDE;4-AMINOBENZHYDRAZIDE;N,4-Diaminobenzamide
- CBNumber:
- CB8434256
- Summenformel:
- C7H9N3O
- Molgewicht:
- 151.17
- MOL-Datei:
- 5351-17-7.mol
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4-Aminobenzohydrazid Eigenschaften
- Schmelzpunkt:
- 225-227 °C (lit.)
- Siedepunkt:
- 273.17°C (rough estimate)
- Dichte
- 1.2100 (rough estimate)
- Brechungsindex
- 1.5860 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Löslichkeit
- DMF: 10 mg/ml; DMSO: 14 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
- Aggregatzustand
- Crystals or Powder
- pka
- 13.05±0.10(Predicted)
- Farbe
- White or beige
- Wasserlöslichkeit
- Soluble in DMSO (10 mg/ml), dilute acids, and water (partly miscible).
- BRN
- 639053
- CAS Datenbank
- 5351-17-7(CAS DataBase Reference)
- NIST chemische Informationen
- Benzoic acid, 4-amino-, hydrazide(5351-17-7)
4-Aminobenzohydrazid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
4-Aminobenzoic acid hydrazide (4-ABAH) is an irreversible inhibitor of myeloperoxidase (MPO; IC
50 = 0.3 μM). It reduces the production of hypochlorous acid (HOCl) induced by opsonized zymosan or phorbol 12-myristate 13-acetate (PMA; ) in isolated human neutrophils with IC
50 values of 16 and 2.2 μM, respectively. 4-ABAH inhibits PMA-induced formation of neutrophil extracellular traps (NETs) in the same cells. It reduces infarct volume and the severity of neurological deficits, as well as increases survival, in a mouse model of cerebral ischemia induced by transient middle cerebral artery occlusion (MCAO) when administered at a dose of 40 mg/kg twice per day.
Chemische Eigenschaften
White or beige crystals or powder
Verwenden
4-Aminobenzhydrazide has an important role in the peroxidation activity of MPO. It is also used in enzyme preparations and in cell cultures.
4-Aminobenzohydrazid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Aminobenzohydrazid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 159)Lieferanten
5351-17-7(4-Aminobenzohydrazid)Verwandte Suche:
- 4-AMINOBENZHYDRAZIDE
- 4-AMINOBENZOHYDRAZIDE
- 4-AMINOBENZOYLHYDRAZIDE
- 4-AMINO-BENZOIC ACID HYDRAZIDE
- 4-AMINOBENZOIC HYDRAZIDE
- TIMTEC-BB SBB007555
- P-AMINOBENZOYL HYDRAZIDE
- P-AMINOBENZOHYDRAZIDE
- P-AMINOBENZHYDRAZIDE
- 4-amino-benzoicacihydrazide
- 4-Aminobenzoylhydrazine
- Amben hydrazide
- 4-Aminobenzoic acid hydrazide~(4-Aminobenzoyl)hydrazine
- 4-Aminobenzhydrazide, 98+%
- benzoic acid, 4-amino-, hydrazide
- AMino benzoyl hydrazine
- (4-AMinobenzoyl)hydrazide, 95% 5GR
- 4-AMinobenzoic hydrazide 95%
- 4NPhCON2
- Benzoic acid, 4-amino-, hydrazide (9CI)
- WLN: ZNUYQR DZ
- N,4-Diaminobenzamide
- (4-Aminobenzoyl)hydrazide,95%
- ambenhydrazide
- aminostimil
- Benzoic acid, p-amino-, hydrazide
- p-Amino benzoyl hydrazine
- p-Aminobenzoic hydrazide
- p-amino-benzoicacihydrazide
- p-aminobenzoylhydrazine
- para-Aminobenzhydrazide
- LABOTEST-BB LT00010042
- MYELOPEROXIDASE INHIBITOR-I
- P-AMINOBENZOIC ACID HYDRAZIDE
- Myeloperoxidase Inhibitor
- 4-Aminobenzohydrazide >
- 4-POBN
- Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem
- 5351-17-7
- H2NC6H4CONHNH2
- C7H9ON3
- Building Blocks
- Carbonyl Compounds
- Organic Building Blocks
- Hydrazides
- Carbonyl Compounds
- Hydrazides
- Organic Building Blocks
- Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes
- Amines
