α-Tocopherylhydrogensuccinat
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- CAS-Nr.
- 4345-03-3
- Bezeichnung:
- α-Tocopherylhydrogensuccinat
- Englisch Name:
- D-α-Tocopherol succinate
- Synonyma:
- VE;VITAMIN E SUCCINATE;VES;TOCOPHEROL SUCCINATE;α-Tocopheryl Succinate;D-A-TOCOPHEROL SUCCINATE;ALPHA-TOCOPHERYL SUCCINATE;D-alpha-Tocopheryl;D-ALPHA-TOCOPHERYL SUCCINATE;D-ALPHA-TOCOPHEROL SUCCINATE
- CBNumber:
- CB8483476
- Summenformel:
- C33H54O5
- Molgewicht:
- 530.78
- MOL-Datei:
- 4345-03-3.mol
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α-Tocopherylhydrogensuccinat Eigenschaften
- Schmelzpunkt:
- ~76 °C(lit.)
- Siedepunkt:
- 625.8±55.0 °C(Predicted)
- Dichte
- 1.002±0.06 g/cm3(Predicted)
- Dampfdruck
- 0Pa at 20℃
- storage temp.
- -20°C
- Löslichkeit
- Practically insoluble in water, very soluble in methylene chloride, soluble in acetone and in anhydrous ethanol.
- pka
- 4.35±0.17(Predicted)
- Farbe
- White or off-white
- Geruch (Odor)
- Little or no odor
- maximale Wellenlänge (λmax)
- 286nm(EtOH)(lit.)
- Merck
- 14,9495
- BRN
- 4038233
- Stabilität:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
- LogP
- 12 at 25℃
- CAS Datenbank
- 4345-03-3(CAS DataBase Reference)
- EPA chemische Informationen
- D-.alpha.-Tocopheryl acid succinate (4345-03-3)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| WGK Germany |
1 |
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| RTECS-Nr. |
EJ9984000 |
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| F |
8-10-23 |
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| HS Code |
2936280000 |
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| Toxizität |
LD50 oral in rat: > 7gm/kg |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P304+P340 |
BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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α-Tocopherylhydrogensuccinat Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Off-White to Pale Yellow Solid
Verwenden
A potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand). It inhibits proliferation of mesothelioma cells
by selective down-regulation of fibroblast growth factor receptors. Furthermore, it has been shown to enhance the anti-tumor effect of dendritic cell vaccines.
Allgemeine Beschreibung
White powder.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
Vitamin E succinate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Brandgefahr
Flash point data for Vitamin E succinate are not available; however, Vitamin E succinate is probably combustible.
Sicherheitsprofil
When heated to
decomposition it emits acrid smoke and
irritating fumes.
α-Tocopherylhydrogensuccinat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
α-Tocopherylhydrogensuccinat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 311)Lieferanten
4345-03-3(α-Tocopherylhydrogensuccinat)Verwandte Suche:
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ylacetat
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
Retinylpalmitat
9,10-Secocholesta-5,7,10(19)-trien-3-ol
Menadion
Cocarboxylase
Vitamin A
Ascorbinsure
α-Tocopherol
6alpha-Methylprednisolone sodium succinate
Diethylstilbestrol
Vitamin E
α-Tocopherylacetat
9,10-Secoergosta-5(Z),7(E),10(19)-trien-3β-ol
Vitamin E
Thiamin
(±)-(3-Amino-3-carboxypropyl)dimethylsulfoniumchlorid
Calciumpantothenat , D-Form
- 1210IU D-α-Tocopherol succinate,vitamin E succinate 1185IU D-α-Tocopherol succinate,vitamin E succinate
- (+)-α-TOCOPHEROL ACID SUCCINATE
- D-α-Tocopheryl succinate, Ph. Eur.
- [2theta-[2theta(4theta,8theta)]]-cyl)-2h-1-benzopyran-6-yl]este
- alpha-tocopherol,succinate
- alpha-tocopherolhemisuccinate
- butanedioicacid,mono(3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltride
- butanedioicacid,mono[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltride
- mono[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]ester,[2R-Butanedioicacid
- succinicacid,mono(2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chroma
- VitamineEsuccinate
- vitaminehemisuccinate
- VITAMIN E ACID SUCCINATE
- A-TOCOPHEROL ACID SUCCINATE
- DL-ALPHA-TOCOPHEROL SUCCINATE
- D-ALPHA-TOCOPHERYL ACID SUCCINATE
- D-ALPHA-TOCOPHEROL ACID SUCCINATE
- D-A-TOCOPHERYL ACID SUCCINATE
- (+)-A-TOCOPHEROL ACID SUCCINATE FROM
- -2,5,7,8-tetramethyl-2-((4R,8R)
- -4,8,12-trimethyltridecyl)
- 4-Oxo-4-(((R)
- chroman-6-yl)
- ALPHA-TOCOPHERYL ACID SUCCINATE
- (+)-ALPHA-TOCOPHEROL ACID SUCCINATE
- (+)-nyl)este
- (2r-(2r*(4r*,8r*)))-cyl)-2h-1-benzopyran-6-yl)este
- D-α-Tocopherol succinate
- (+)-A-tocopherol acid succinate from*natural A-to
- alpha-tocopheryl hydrogen succinate
- D-a-Tocopherol acid Succinate
- Solid vitamin E-Natural vitamin E Succinate
- a-Tocopheryl acid succinate
- Butanedioic acid, mono(3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1- benzopyran-6-yl) ester, (2R-(2R*(4R*,8R*)))
- Succinic acid, mono(2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl) ester, (+)
- 4-[[(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran]-6-yloxy]-4-oxobutanoic acid
- Succinic acid hydrogen 1-[(2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl] ester
- α-Tocopherol acidic succinate
- D-alpha-Tocopheryl acid succinate,99+%
- Vitamin E succinat (d-alpha-tocopheryl hydrogen succinat)
- Alpha Tocopheryl Acid Succinate (250 mg) (Vitamin E Succinate)
- VITAMIN E SUCCINATE(TOCOPHEROL SUCCINATE)(P)
- (+)-2,5,7,8-TetraMethyl-2-(4,8,12-triMethyltridecyl)-6-chroManol Hydrogen Succinate
- Butanedioic Acid 1-[(2R)-3,4-Dihydro-2,5,7,8-tetraMethyl-2-[(4R,8R)-4,8,12-triMethyltridecyl]-2H-1-benzopyran-6-yl] Ester
- Covitol 1210
- CV 104
- VitaMin E d-α-Tocosuccinate
- Tocopheryl Acid Succinate, a
- RRR-α-Tocopheryl hydrogen succinate
- (+)-A-TOCOPHEROL ACID SUCCINATE FROM*NAT URAL A-TOCO
- D-ALPHA TOCOPHEROL SUCCINATE, 100MG, NEA T
- D-α-TOCOPHERYL SUCCINATE
- D-alpha-Tocopherylacidsuccinate=TAS
- D-ALPHA-TOCOPHERYLHEMISUCCINATE
- DL-ALPHA-TOCOPHEROLACIDSUCCINATE
- ALL-RAC-ALPHA-TOCOPHEROLSUCCINATE
- ALPHA-TOCOPHERYLHEMISUCCINATE
- RRR-ALPHA-TOCOPHERYLSUCCINATE
