4-O-α-D-Glucopyranosyl-D-glucitol

Maltitol Struktur
585-88-6
CAS-Nr.
585-88-6
Bezeichnung:
4-O-α-D-Glucopyranosyl-D-glucitol
Englisch Name:
Maltitol
Synonyma:
D-MALTITOL;malbit;MALTITOL-BASEDPRODUCTS;titoL;maltit;maltimr;MALTITOL;maltisorb;amaltymr100;amaltisyrup
CBNumber:
CB8726683
Summenformel:
C12H24O11
Molgewicht:
344.31
MOL-Datei:
585-88-6.mol

4-O-α-D-Glucopyranosyl-D-glucitol Eigenschaften

Schmelzpunkt:
149-152 °C (lit.)
alpha 
[α]D20 +106~+108゜ (c=0.8, H2O)
Siedepunkt:
399.42°C (rough estimate)
Dichte
1.3863 (rough estimate)
Dampfdruck
0.001Pa at 20℃
Brechungsindex
105 ° (C=10, H2O)
storage temp. 
2-8°C
Löslichkeit
Very soluble in water, practically insoluble in anhydrous ethanol.
Aggregatzustand
Crystalline Powder
pka
12.84±0.70(Predicted)
Farbe
White
Wasserlöslichkeit
Soluble in water. Slightly soluble in ethanol.
BRN 
89983
Stabilität:
Hygroscopic
LogP
-3.87 at 24℃
CAS Datenbank
585-88-6(CAS DataBase Reference)
EPA chemische Informationen
D-Glucitol, 4-O-.alpha.-D-glucopyranosyl- (585-88-6)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
S-Sätze: 24/25
WGK Germany  3
RTECS-Nr. LZ4394000
TSCA  Yes
HS Code  29400090
Giftige Stoffe Daten 585-88-6(Hazardous Substances Data)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

4-O-α-D-Glucopyranosyl-D-glucitol Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.

Beschreibung

Maltitol is a-D-glucopyranosyl-1.4-glucitol. The solubility in water is approximately 1,750 g/L at room temperature. Maltitol is stable under the common processing conditions of foods. In addition to dry maltitol several types of syrups are available.
Maltitol is, depending on the concentration, approximately 90 % as sweet as sucrose and noncariogenic.
In the European Union, maltitol is approved as E 965 for a large number of food applications. It is GRAS in the United States and also approved in many other countries.

Chemische Eigenschaften

Maltitol is a-D-glucopyranosyl-1.4-glucitol. The solubility in water is approximately 1,750 g/L at room temperature. Maltitol is stable under the common processing conditions of foods. In addition to dry maltitol several types of syrups are available.
Maltitol is, depending on the concentration, approximately 90 % as sweet as sucrose and noncariogenic .
In the European Union, maltitol is approved as E 965 for a large number of food applications. It is GRAS in the United States and also approved in many other countries.

Verwenden

Maltitol is a polyhydric alcohol (polyol) produced by hydrogenation of maltose. it is approximately 90% as sweet as sucrose, has good stability, and is nonhygroscopic. uses include chewing gum, dry nut bakery products, and chocolate.

Definition

ChEBI: An alpha-D-glucoside consisting of D-glucitol having an alpha-D-glucosyl residue attached at the 4-position. Used as a sugar substitute.

Vorbereitung Methode

Maltitol is produced by chemical hydrogenation of maltose, which can be obtained by enzymatic degradation of starch under conditions similar to those used for other starch hydrolysates such as glucose. The Starting material can be the different commercially available starches including corn, potato, and others. A partially degraded starch, which can be obtained by treatment with diluted hydrochloric or sulphuric acid and subsequent neutralization or with heat-stable a-amylase, is then subjected to enzyme treatment for further degradation to maltose-rich products.
Enzymes used for maltose production are b-amylases, fungal a-amylases, a-1.6- glucosidases, maltogenic amylases, and debranching enzymes, preferably with high temperature optimum.

Allgemeine Beschreibung

Maltitol is a low-caloric artificial sweetener, consisting of a sugar alcohol (polyol),

Pharmazeutische Anwendungen

Maltitol is widely used in the pharmaceutical industry in the formulation of oral dosage forms. It is a noncariogenic bulk sweetener, approximately as sweet as sucrose, well adapted as a diluent for different oral dosage forms, wet granulation, and sugarfree hard coating.

Sicherheit(Safety)

Maltitol is used in oral pharmaceutical formulations, confectionery, and food products, and is considered to be noncariogenic. It is generally regarded as a nontoxic, nonallergenic, and nonirritant material.
Digestion of maltitol follows two different metabolic pathways: absorption in the small intestine and fermentation in the large intestine (colon). These two metabolic pathways must thus be considered when evaluating the energy value. The hydrolysis of maltitol in the small intestine releases sorbitol and glucose. Glucose is actively transported and rapidly absorbed, whereas sorbitol absorption is passive. The nonabsorbed sorbitol and nonhydrolyzed maltitol are fermented by the microflora in the colon. The relative importance of the two absorption pathways depends on numerous individual factors and is related to the quantity of maltitol ingested. Excessive oral consumption (>50 g daily) may cause flatulence and diarrhea.
Maltitol exhibits a low glycemic index and can therefore, under medical supervision, have a place in the diet of diabetic patients. The intake of maltitol must be taken into account for the calculation of the daily glucidic allowance.
The WHO, in considering the safety of maltitol, did not set a value for the acceptable daily intake since the levels used in food to achieve a desired effect were not considered a hazard to health.

Lager

Maltitol has good thermal and chemical stability. When it is heated at temperatures above 200°C, decomposition begins (depending on time, temperature, and other prevailing conditions). Maltitol does not undergo browning reactions with amino acids, and absorbs atmospheric moisture only at relative humidities of 89% and above, at 20°C.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in oral pharmaceutical formulations. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

4-O-α-D-Glucopyranosyl-D-glucitol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


4-O-α-D-Glucopyranosyl-D-glucitol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 473)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
QINGDAO HONG JIN CHEMCIAL CO.,LTD.
532-83657313
hjt@hong-jin.com China 228 58
Mainchem Co., Ltd.
--
sarah@mainchem.com China 6572 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5988 58
Hebei Jingbo New Material Technology Co., Ltd
+8619931165850
hbjbtech@163.com China 1000 58
Shandong Juchuang Chemical Co., LTD
+86-18885615001 +86-18885615001
admin@juchuangchem.com China 387 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+86-13474506593 +86-13474506593
sarah@tnjone.com China 185 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21700 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9354 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3012 60
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763
info@tnjchem.com China 2989 55

585-88-6(4-O-α-D-Glucopyranosyl-D-glucitol)Verwandte Suche:


  • 4-O-.alpha.-D-GlucopyronosylD-sorbitol
  • GLUCITOL,4-O-ALPHA-D-GLUCOPYRANOSYL,D-
  • MALTITOLSYRUP
  • 4-o-alpha-d-glucopyranosyl-d-glucito
  • amaltisyrup
  • amaltymr100
  • d-4-o-alpha-d-glucopyranosylglucitol
  • Alpha-D-Glucopyranosy1-1, 4-D-Glucitol
  • 6-O-A-D-GALACTOPYRANOSYL-D-GLUCOPYRANOSE
  • Maltitol syruo
  • Maltitol,95%
  • 4-.alpha.-D-Glucopyranosyl-D-sorbitol
  • 4-O-alpha-Glucopyranosyl-D-glucitol
  • D-Maltitol ,98%
  • Maltitol,4-O-α-Glucopyranosyl-D-sorbitol
  • Maltitol (200 mg)
  • Maltitol, 95% 25GR
  • Maltsugar alcohol
  • maltimr
  • maltisorb
  • maltit
  • MALTITOL
  • 4-O-ALPHA-D-GLUCOPYRANOSYL-D-GLUCITOL
  • 4-O-ALPHA-GLUCOPYRANOSYL-D-SORBITOL
  • D-Glucitol, 4-O-.alpha.-D-glucopyranosyl-
  • 4-o-à-d-glucopyranosyl-d-glucitol
  • 4-o-α-glucopyranosyl-d-sorbitol
  • 4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,5,6-pentol
  • GLUCOPYRANOSYLSORBITOL
  • HYDROGENATEDGLUCOSESYRUP
  • MALTITOL CRYSTALLINE DRY FORM
  • MALTIT 98%, KRIST.
  • MALTITOL, CRYSTALLIZED
  • MALTITOL, USP STANDARD
  • MALTITOL, EP STANDARD
  • Maltitol,97%
  • Maltitol Syrup 585-88-6 kf-wang(at)kf-chem.com
  • D-Glucitol, 4-O-a-D-glucopyranosyl-
  • titoL
  • Maltitol Solution 50%
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  • LIQUID MALTITOL FOOD
  • Maltitol Crystal
  • Maltitol USP/EP/BP
  • Wholesale Price Maltitol Powder / Syrup 75% 80% CAS No 585-88-6
  • Mannitol EP Impurity B
  • Maltitol (1374907)
  • MALTITOL-BASEDPRODUCTS
  • malbit
  • D-MALTITOL
  • 4-O-α-glucopyranosyl-D-sorbitol
  • Maltitol powder Maltitol
  • 4-O-α-D-glucopyranosyl-D-glucitol (D-maltitol)
  • D-Glucitol, 4-O-α-D-glucopyranosyl-
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