Halcinonid
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- CAS-Nr.
- 3093-35-4
- Bezeichnung:
- Halcinonid
- Englisch Name:
- Halcinonide
- Synonyma:
- halog;halcort;halcimat;Adcortin;SQ 18566;halciderm;Alcinonide;The sinai,;HALCINONIDE;Halcinonida
- CBNumber:
- CB9106428
- Summenformel:
- C24H32ClFO5
- Molgewicht:
- 454.96
- MOL-Datei:
- 3093-35-4.mol
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Halcinonid Eigenschaften
- Schmelzpunkt:
- 264-265° (dec)
- alpha
- D25 +155° (CHCl3)
- Siedepunkt:
- 564.3±50.0 °C(Predicted)
- Dichte
- 1.1567 (estimate)
- storage temp.
- -20°C Freezer
- Löslichkeit
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- Aggregatzustand
- Solid
- pka
- 13.19±0.70(Predicted)
- Farbe
- White to Off-White
- InChIKey
- MUQNGPZZQDCDFT-JNQJZLCISA-N
- SMILES
- O1[C@]2([H])C[C@]3([H])[C@@](C)([C@]2(C(CCl)=O)OC1(C)C)C[C@H](O)[C@]1(F)[C@]2(C)C(=CC(=O)CC2)CC[C@@]31[H]
- CAS Datenbank
- 3093-35-4(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
63 |
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| S-Sätze: |
36 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
TU5010200 |
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| HS Code |
2937220000 |
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| Toxizität |
LD50 i.p. in mice: 150 mg/kg (Millonig, Yiakas) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H361 |
Kann vermutlich die Fruchtbarkeit beeinträchtigen oder das Kind im Mutterleib schädigen. |
Reproduktionstoxizität |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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Halcinonid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
Anti-inflammatory (topical).
Indications
Halcinonide (Halog, Halog-E) is a synthetic fluorinated corticosteroid.
Allgemeine Beschreibung
Halcinonide, 21-chloro-9-fluoro-11β-hydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione, was the first chloroGC marketed. Likemany other potent GCs, it is used only topically.
Halcinonid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Lithiumchlorid
Methansulfonylchlorid
Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11,16,17-trihydroxy-, (11β,16α)-
Pregn-4-ene-3,20-dione, 21-chloro-9,11-epoxy-16,17-[(1-methylethylidene)bis(oxy)]-, (9β,11β,16α)-
9-Fluor-11β,21-dihydroxy-16α,17-(isopropylidendioxy)pregn-4-en-3,20-dion
Downstream Produkte
Halcinonid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 278)Lieferanten
3093-35-4(Halcinonid)Verwandte Suche:
- 20-dione,21-chloro-9-fluoro-11-beta,16-alpha,17-trihydroxy-pregn-4-ene-cyc
- halciderm
- halcimat
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-beta,16-alpha,17-trihydroxy, cyclic-16,17-acetal with acetone
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)-
- 21-Chloro-9α-fluoro-11β-hydroxy-16α,17α-(isopropylidenebisoxy)pregn-4-ene-3,20-dione
- Halcinonide (200 mg)
- (11β,16α)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-Methylethylidene)bis(oxy)]
pregn-4-ene-3,20-dione
- halcort
- halog
- lic16,17-acetalwithacetone
- (11b,16a)-21-chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregn-4-ene-3,20-dione
- 2H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv.
- Adcortin
- Alcinonide
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11β,16α,17-trihydroxy-, cyclic 16,17-acetal with acetone (7CI, 8CI)
- SQ 18566
- HALCINONIDE
- 21-chloro-9-alpha-fluoro-11-beta-hydroxy-16-alpha,17-alpha-isopropylidenedioxypregn-4-ene-3,20-dione
- Halcinonide CP2000
- Halcinonide Impurity
- Halcinonida
- Pregn-4-ene-3,20-dione,21-chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,(11b,16a)-
- (6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-8b-(2-chloroacetyl)-6b-fluoro-7-hydroxy-6a,8a,10,10-tetramethyl-5,6,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one
- Halcinonide USP/EP/BP
- Halcinonide (1302509)
- The sinai,
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-
- Pregn-4-ene-3,20-dione,21-chloro-9-fluoro-11-hydroxy-16,Chemicalbook17-((1-methylethylidene)bis(oxy))-,(11beta,16alpha)-
- 21-Chloro-9α-fluoro-11β-hydroxy-16α,17α-(isopropylidenebisoxy)pregn-4-ene-3,20-dione
- (11β,16α)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-Methylethylidene)bis(oxy)]p
- 3093-35-4
- 3903-35-4
- C24H32ClFO5
- API
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
- Steroid Hormones
- Organics
- Cortisone
- Hormones
