1-Deoxynojirimycin
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- CAS-Nr.
- 19130-96-2
- Englisch Name:
- 1-Deoxynojirimycin
- Synonyma:
- DNJ;moranoline;DEOXYNOJIRIMYCIN;Sepetaprost;Duvoglustat;DNM;S-GI;moranolin;bay-h5595;uvoglusta
- CBNumber:
- CB9128150
- Summenformel:
- C6H13NO4
- Molgewicht:
- 163.17
- MOL-Datei:
- 19130-96-2.mol
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1-Deoxynojirimycin Eigenschaften
- Schmelzpunkt:
- 195-196°C
- Siedepunkt:
- 361.1±42.0 °C(Predicted)
- Dichte
- 1.456±0.06 g/cm3(Predicted)
- Dampfdruck
- 0Pa at 25℃
- RTECS-Nr.
- TN4350300
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- Löslichkeit
- Soluble in Water up to 25 mg/ml).
- pka
- 13.77±0.70(Predicted)
- Aggregatzustand
- Powder
- Farbe
- White
- Wasserlöslichkeit
- Soluble in water, dimethyl sulfoxide and methanol.
- BRN
- 3588039
- Stabilität:
- Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
- LogP
- -1.8
- CAS Datenbank
- 19130-96-2(CAS DataBase Reference)
1-Deoxynojirimycin Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White Crystalline Solid
Verwenden
An alpha-glucosidase inhibitor. Interferes with normal processing of N-linked glycoproteins.(+)-1-Deoxynojirimycin acts as an inhibitor of alfa-glucosidase I and II and maltase-glucoamylase. It also inhibits mammalian glucosidase, intestinal and lysosmal, beta-glucosidase from sweet almonds, pancreatic alfa-amylase and amyloglucosidase. Further, it serves as a enzyme enhancer for the treatment of Fabry and Pompe disease.
Definition
ChEBI: An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration.
Biologische Aktivität
Inhibitor of glucosidase I (K i = 2.1 mM) and II (K i = 7 mM).
1-Deoxynojirimycin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-Deoxynojirimycin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 377)Lieferanten
19130-96-2()Verwandte Suche:
Cefalotinnatrium
Natriumdesoxycholat
Oxytetracycline dihydrate
Clindamycin
Droperidol
Gentamicin
[4S-(4α,4aα,5aα,12aα)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacen-2-carboxamidmonohydrochlorid
Trichlorethylen
2,2,6,6-Tetramethyl-4-piperidylamin
Chlortetracyclin
Azithromycin
gamma-(4-(p-Chlorphenyl)4-hydroxy-piperidino)-p-fluorbutyrophenon
Diphenoxylat
Piperidin
1,5-Didesoxy-1,5-[(2-hydroxyethyl)imino]-D-glucitol
1,5-Didesoxy-1,5-[[2-[4-(ethoxycarbonyl)phenoxy]ethyl]imino]-D-glucitol
1-Deoxynojirimycin
- (2r,3r,4r,5s)-2-hydroxymethyl-3,4,5-trihydroxypiperidine
- 5-piperidinetriol,2-(hydroxymethyl)-,(2r-(2alpha,3beta,4alpha,5beta))-4
- bay-h5595
- moranolin
- (+)-1-DEOXYNOJIRIMYCIN
- 1-DEOXYNOJIRIMYCIN
- (2R,3R,4R,5S)-2-(HYDROXYMETHYL)-3,4,5-PIPERIDINETRIOL
- (2R,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol
- DNM
- DEOXYNOJIRIMICIN
- 1-DNJ , 1-DEOXYNOJIRIMYCIN
- 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2R,3R,4R,5S)-
- 1-Deoxynojirimycin min. 99%
- 1-DeoxynojiriMycin, froM MorusalbaL.
- 1,5-Dideoxy-1,5-imino-D-sorbitol
- Monoclonal Anti-DNM1 antibody produced in mouse
- 1,5-dideoxy-1,5-imino-d-glucito
- 1,5-dideoxy-1,5-imino-d-glucitol
- 1-deoxynojirimicin
- 1-deoxy-nojirimyci
- 5-amino-1,5-dideoxy-d-glycopyranose
- 5-dideoxy-5-amino-d-glucopyranos
- 5-piperidinetriol(2r-(2alpha,3beta,4alpha,5beta))-2-(hydroxymethyl)-4
- DEOXYNOJIRIMYCIN(SH)
- DESOXYNOJIRIMYCIN
- 1-DEOXYNOJIRIMYCIN,98%
- 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,5beta))-
- D-Glucitol,-1,5-dideoxy-1,5-imino
- (2R)-3α,4α,5α-Trihydroxypiperidine-2α-methanol
- (2R,3S,4R,5R)-3,4,5-Trihydroxypiperidine-2-methanol
- 1-Deoxy-5-O-aza-D-talopyranose
- 1-Deoxy-D-talo-nojirimycin
- BAY-n-5595
- (2S)-2β-(Hydroxymethyl)-3α,4β,5α-piperidinetriol
- (2S)-3α,4β,5α-Trihydroxypiperidine-2β-methanol
- (3R)-6α-(Hydroxymethyl)piperidine-3β,4α,5β-triol
- 1,5-Dideoxy-1,5-epimino-L-glucitol
- 6α-(Hydroxymethyl)piperidine-3β,4α,5β-triol
- (2R,3R,4R,5S)-2-methylolpiperidine-3,4,5-triol
- 5-AMino-1,5-dideoxy-D-glucopyranose
- Antibiotic S-GI
- S-GI
- 1-Deoxynojirimycin DNJ
- Ramulus Mori
- NojiriMycin, 1-deoxy-
- 1-DeoxynojiriMycin (1-DNJ)
- 1-Deoxynojirimycin, 98%, from MorusalbaL.
- 1-Deoxynojirimycin 1%
- (70956-02-4) 1-deoxynojirimycin
- 1-Deoxynojirimycin 19130-96-2
- Dried mulberry leaves extract/morus alba leaves extract
- 1-Deoxynojirimycin USP/EP/BP
- Miglitol Impurity 3（Deoxynojirimycin）
- 1-Deoxynojirimycin, ≥95%
- moranoline
- DNJ
- DEOXYNOJIRIMYCIN
- Sepetaprost
