N,N-Dimethyl-p-phenyl-azoanilin Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
GELBE KRISTALLE.
CHEMISCHE GEFAHREN
Zersetzung beim Erhitzen unter Bildung von Stickstoffoxiden.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Verschlucken.
INHALATIONSGEFAHREN
Verdampfung bei 20°C vernachlässigbar; eine gesundheitsschädliche Partikelkonzentration in der Luft kann jedoch beim Dispergieren schnell erreicht werden.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz reizt die Augen, die Haut und die Atemwege.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Wiederholter oder andauernder Hautkontakt kann Dermatitis hervorrufen. Möglicherweise krebserzeugend für den Menschen.
LECKAGE
Persönliche Schutzausrüstung: Atemschutzgerät, P2-Filter für schädliche Partikel. Verschüttetes Material in Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern.
R-Sätze Betriebsanweisung:
R25:Giftig beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
R68:Irreversibler Schaden möglich.
R45:Kann Krebs erzeugen.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S22:Staub nicht einatmen.
Beschreibung
4-N,N-Dimethylaminobenzene diazonium chloride is a
diazo compound found in diazo copy paper. It is
allergenic only when unexposed.
Chemische Eigenschaften
yellow to orange crystalline powder
Verwenden
For determination of free HCl in gastric juice; spot test identification of peroxidized fats; pH indicator (red 2.9, yellow 4.0).
synthetische
aniline diazotization, and N,N-dimethylaniline coupling.
Vorbereitung Methode
4-Dimethylaminoazobenzene was produced in large quantities
in the early 1900s but is currently not produced in
any significant commercial quantity in the United States.
Definition
A banned food coloring.
Allgemeine Beschreibung
Yellow crystalline leaflets or an orange powder.
Air & Water Reaktionen
Dust may form an explosive mixture in air. Insoluble in water.
Reaktivität anzeigen
Solvent Yellow 2 can detonate, particularly if sensitized by the presence of metal salts or strong acids. May form toxic gases with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. May form flammable gases with alkali metals. May react explosively with strong oxidizing agents, metal salts, peroxides, and sulfides. May react explosively with strong oxidizing agents, metal salts, peroxides, and sulfides.
Hazard
Carcinogen.
Health Hazard
4-Dimethylamino-azobenzene (XIII) is the parent compound of the amino-azo dye carcinogens; it is also known in the earlier literature as Butter Yellow, because it was used to color butter and vegetable oils before its carcinogenic activity was discovered. Many derivatives of XIII have been prepared and tested for carcinogenic activity. In the rat, the amino-azo dye carcinogens, administered in the diet, specifically induce hepatomas. Tumor induction by most of the amino-azo dyes is delayed or inhibited by high dietary levels of riboflavin (vitamin B2) or protein. Replacement of the –N=N– azo linkage by –CH=CH–, as in 4-dimethylaminostilbene (XIV), results in widening the target tissue spectrum; XIV induces tumors in the liver, mammary gland, and ear duct. Mice are much more resistant than rats to the carcinogenic activity of both amino-azo dyes and aminostilbenes.
Brandgefahr
Flash point data for Solvent Yellow 2 are not available. Solvent Yellow 2 is probably combustible.
Sicherheitsprofil
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, and tumorigenic data. Poison
by ingestion and intraperitoneal routes.
Experimental teratogenic and reproductive
effects. Human mutation data reported.
When heated to decomposition it emits
toxic fumes of NOx
Carcinogenicity
4-Dimethylaminoazobenzene is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity fromstudies in experimental animals.
Environmental Fate
Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and
Lewis, 1987).
At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities
were 249, 140, 83, and 48 mg/g, respectively (Dobbs and Cohen, 1980).
läuterung methode
Crystallise the dye from acetic acid or isooctane, or from 95% EtOH by adding hot water and cooling. Dry it over KOH under vacuum at 50o. [Beilstein 6 IV 448.] CARCINOGEN.
N,N-Dimethyl-p-phenyl-azoanilin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Natriumacetat
Xylidine
benzenediazonium
N,N,N',N'-Tetramethyl-4,4'-azodianilin
N,N-Dimethyl-4-nitroanilin
1-[4-(dimethylamino)phenyl]propan-1-ol
Azidobenzol
N,N,N',N'-Tetramethyl-4,4-methylendianilin
N,N-Dimethyl-p-nitroso-anilin
N,N-Dimethyl-phenylendiamin (p)
N,N-Dimethyl-anilin
Anilin
Downstream Produkte
