Boc-Glycine hydrazide
|
|
|
- CAS-Nr.
- 6926-09-6
- Englisch Name:
- Boc-Glycine hydrazide
- Synonyma:
- BUTTPARK 77\04-08;BOC-GLYCINE HYDRAZIDE;Boc-Glycinehydrazide8%;Boc-Glycinehydrazide，98%;Butoxycarbonylglycine hydrazide;Boc-Glycine hydrazide USP/EP/BP;N-TERT-BUTOXYCARBONYLGLYCYLHYDRAZIDE;tert-Butyl (2-hydrazinyl-2-oxoethyl);2-Aminoacetohydrazide, 2-BOC protected;tert-butyl (2-hydrazino-2-oxoethyl)carbamate
- CBNumber:
- CB9323340
- Summenformel:
- C7H15N3O3
- Molgewicht:
- 189.21
- MOL-Datei:
- 6926-09-6.mol
|
Boc-Glycine hydrazide Eigenschaften
- Schmelzpunkt:
- 111-115
- Siedepunkt:
- 386.5±25.0 °C(Predicted)
- Dichte
- 1.139±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Aggregatzustand
- solid
- pka
- 11.40±0.46(Predicted)
- Farbe
- Beige
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xi,Xn |
|
|
| R-Sätze: |
22 |
|
|
| HazardClass |
IRRITANT |
|
|
| HS Code |
2928009090 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P271 |
Nur im Freien oder in gut belüfteten Räumen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
|
Boc-Glycine hydrazide Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Boc-Glycine hydrazide is used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthese
N-Protected Hydrazides 2a-l; General Procedure The protected amino acid 1 (2 equiv) and EDAC (2 equiv) were dissolved in the minimum amount of CH2Cl2 at 0 ??C. The mixture was stirred at 0 ??C for 2 h. PhthNNH2 (1 equiv) was added and the mixture was stirred at 0 ??C for 1 h and then at r.t. overnight. Distillation of the solvent under reduced pressure gave a product which was dissolved in EtOAc and washed successively with 1 M KHSO4, sat. aq NaHCO3, and brine. The organic layer was then dried (Na2SO4), filtered, and concentrated in vacuo. The residue was precipitated with Et2O to yield compound 2. If necessary, the residue was purified by column chromatography (silica gel, hexane- EtOAc, 3:7 to 7:3). Compounds 4a-l; General Procedure Aminomethylated polystyrene resin (3 equiv; 1.1 mmol/g, 100-200 mesh) was conditioned for 10 min at r.t. in CH2Cl2. Then 2 (1 equiv) was added, and the mixture was slowly stirred for 24 h at r.t. The mixture was filtered and the solvent was evaporated in vacuo to give product 4. Compound 4h, yield 89%.
Boc-Glycine hydrazide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Boc-Glycine hydrazide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 110)Lieferanten
6926-09-6()Verwandte Suche:
Betain
Glycin
Nifuroxazid
Decanedihydrazide
4-(Diethylamino)salicylaldehyd
Tebufenozide
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
5-Chlorvaleriansaeure
Pyridazin-3,6-diol
Pralmorelin
N-(tert-Butoxycarbonyl)glycin
4,4-Bis(4-hydroxyphenyl)valeriansure
Adipohydrazid
1,5-Diphenylcarbonohydrazid
Carbonohydrazid
2,3-Dihydrophthalazin-1,4-dion
Formylhydrazin
2',3-Bis[[3-[3,5-di-tert-butyl-4-hydroxyphenyl]propionyl]]propionohydrazid
- BOC-GLYCINE HYDRAZIDE
- BUTTPARK 77\04-08
- N-TERT-BUTOXYCARBONYLGLYCYLHYDRAZIDE
- Butoxycarbonylglycine hydrazide
- 2-Aminoacetohydrazide, 2-BOC protected
- tert-Butyl (2-hydrazino-2-oxoethyl)carbamate, 2-[(tert-Butoxycarbonyl)amino]acetohydrazide
- HydrazinocarbonylMethyl-carbaMic acid tert-butyl ester, 95%+
- tert-butyl (2-hydrazino-2-oxoethyl)carbamate
- tert-butyl N-(2-hydrazino-2-oxo-ethyl)carbamate
- tert-butyl N-(2-hydrazinyl-2-oxoethyl)carbamate
- tert-butyl N-(2-hydrazinyl-2-oxo-ethyl)carbamate
- tert-Butyl (2-hydrazinyl-2-oxoethyl)
- N-(2-hydrazino-2-keto-ethyl)carbamic acid tert-butyl ester
- N-(2-hydrazino-2-oxoethyl)carbamic acid tert-butyl ester
- Boc-Glycinehydrazide，98%
- Hydrazinocarbonylmethyl-carbamic acid tert-butyl ester
- tert-butyl N-[(hydrazinecarbonyl)methyl]carbamate
- Boc-Glycinehydrazide8%
- Glycine, N-[(1,1-dimethylethoxy)carbonyl]-, hydrazide
- ert-butylN-(2-hydrazinyl-2-oxoethyl)carbamate
- Boc-Glycine hydrazide USP/EP/BP
- 6926-09-6
- 926-09-6
- 6926/9/6
