(S)-1-Boc-3-methylpiperazine
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- CAS-Nr.
- 147081-29-6
- Englisch Name:
- (S)-1-Boc-3-methylpiperazine
- Synonyma:
- tert-butyl (S)-3-methylpiperazine-1-carboxylate;(S)-1-BOC-3-METHYLPIPERAZINE;(S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-4-Boc-2-methylpiperazine;4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID;4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid;CPD2809-SM;(3S)-3-MethyL;(S)-4-N-BOC-2-METHYL;Sotorasib Impurity 2
- CBNumber:
- CB9458934
- Summenformel:
- C10H20N2O2
- Molgewicht:
- 200.28
- MOL-Datei:
- 147081-29-6.mol
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(S)-1-Boc-3-methylpiperazine Eigenschaften
- Schmelzpunkt:
- 40-45 °C
- alpha
- -16 º (c=1 in dioxane)
- Siedepunkt:
- 268.7±15.0 °C(Predicted)
- Dichte
- 0.997±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- pka
- 8.52±0.40(Predicted)
- Aggregatzustand
- Crystalline Powder
- Farbe
- White to yellow
- Optische Aktivität
- [α]/D -16±2°, c = 1 in dioxane
- Sensitive
- Air Sensitive
- InChI
- InChI=1S/C10H20N2O2/c1-8-7-12(6-5-11-8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1
- InChIKey
- FMLPQHJYUZTHQS-QMMMGPOBSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCN[C@@H](C)C1
- CAS Datenbank
- 147081-29-6(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H318 |
Verursacht schwere Augenschäden. |
Schwere Augenschädigung |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P280, P305+P351+P338, P310 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
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(S)-1-Boc-3-methylpiperazine Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
Beschreibung
(S)-1-Boc-3-methylpiperazine is a hydrophobic compound that is structurally modified from the tetracyclic family of drugs. It has been shown to inhibit tumor cell growth by binding to the oncogene, KRASG12C, and downregulating its expression. This compound also inhibits cancer cell growth through the inhibition of the PI3K/AKT signaling pathway. The pharmacological effects of (S)-1-Boc-3-methylpiperazine are dependent on its ability to bind with high affinity to KRASG12C and inhibit its activity.
Chemische Eigenschaften
colorless to yellow liquid
Verwenden
Laboratory chemicals, Manufacture of substances.
(S)-1-Boc-3-methylpiperazine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(S)-1-Boc-3-methylpiperazine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 343)Lieferanten
147081-29-6()Verwandte Suche:
- TERT-BUTYL (S)-3-METHYL-1-PIPERAZINECARBOXYLATE
- (S)-N4-BOC-2-METHYLPIPERAZINE
- (S)-1-TERT-BUTOXYCARBONYL-3-METHYLPIPERAZINE
- (S)-1-N-BOC-3-METHYLPIPERAZINE
- (S)-3-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- (S)-4-N-BOC-2-METHYL PIPERAZINE
- 1-PIPERAZINECARBOXYLIC ACID, 3-METHYL-, 1,1-DIMETHYLETHYL ESTER, (3S)-
- (S)-1-Boc-3-methylpiperazine≥ 99% (HPLC, Chiral purity)
- 4-BOC-2-(S)-METHYL-PIPERAZINE
- (3S)-1-BOC-3-METHYLPIPERAZINE
- (S)-3-Methyl-1-Boc-piperazine
- (S)-4-N-Boc-2-MethylPiperazinee
- (S)-4-N-Boc-2-methylpiperazine
(S)-4-N-Boc-2-methyl piperazine
- (S)-2-METHYL-1-BOC-PIPERAZINE
- (S)-2-Methylpiperazine, N4-BOC protected
- (S)-3-Methylpiperazine, N1-BOC protected
- (S)-4-N-BOC-2-METHYL
- (s)-3-methyl-piperazine-1-carboxylic acid tert-butyl
- (S)-4-N-BOC-2-Methylpiperazine-HCl
- (3S)-3-Methylpiperazine-1-carboxylic acid tert-butyl ester
- tert-Butyl (3S)-3-methylpiperazine-1-carboxylate, (3S)-1-(tert-Butoxycarbonyl)-3-methylpiperazine
- (S)-1-Boc-3-Methylpiperazine
- (S)-1-Boc-3-Methylpiperazine, 98%+
- (3S)-3-Methylpiperazine, N1-BOC protected
- Chemdraw8(S)-3-Methyl-piperazine-1-carboxylic acid tert-butyl ester
- CPD2809-SM
- (3S)-3-MethyL
- (S)-4-N-Boc-2-methylpiperazine ISO 9001：2015 REACH
- (S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE
- (S)-1-BOC-3-METHYLPIPERAZINE
- tert-butyl (S)-3-methylpiperazine-1-carboxylate
- 4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID
- (S)-4-Boc-2-methylpiperazine
- 4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid
- 1-Piperazinecarboxylic acid, 3-methyl-, 1,1-dimethylethyl ester, (3S)- (9CI, ACI)
- 3-methyl-1-Piperazinecarboxylic acid 1,1-dimethylethyl ester (3S)- (9CI ACI)
- 3-Methyl-1-piperazinecarboxylic acid tert-butyl ester (3S)-
- Sotorasib Impurity 2
- 147081-29-6
- Asymmetric Synthesis
- Chiral Building Blocks
- Heterocyclic Building Blocks
- Piperazines
- Piperazines
- pharmacetical
- Piperazine series
- Quinoline series
- Piperaizine
- 147081-29-6
