Chloralose (INN) Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
Beschreibung
Chloralose, (R)-1,2-O-(2,2,2-trichloroethylidene)-
α-D-glucofuranose, is a crystalline powder which is soluble in water,
fairly soluble in alcohol, diethyl ether, glacial acetic acid,
sparingly soluble in chloroform, practically insoluble in
petroleum ether.
Chloralose is produced by reaction of glucose with waterfree
chloral under heating (21).
Chemische Eigenschaften
needle-like crystals or powder
Verwenden
It has been employed widely as an animal anesthetic in the laboratory setting. alpha-chloralose is a true anesthetic or an immobilizing agent with sedative-hypnotic properties has important implications. Canada geese (Branta canadensis) and blue geese (Chen caerulescens) were caught with alpha-chloralose, an oral hypnotic administered on bait. Wild turkeys (Meleagris gallopavo) were captured with alpha-chloralose, an oral anesthetic.
Hazard
May cause addiction, highly toxic.
Sicherheitsprofil
Poison by ingestion,
subcutaneous, and intraperitoneal routes.
Questionable carcinogen with experimental
tumorigenic data. When heated to
decomposition it emits toxic fumes of Cl-.
Stoffwechselwegen
Chloralose is effectively a chloral generator which, in turn, affords trichloroethanol
by metabolism. This is the narcotic agent. Sleep is induced in
mice before death and therefore the compound is regarded as a humane
mouse killer. It is particularly effective when a quick clearout is required
but there is evidence that mice can become tolerant.
Chloralose (INN) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
