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RO-31-8220

RO-31-8220 Struktur
138489-18-6
CAS-Nr.
138489-18-6
Englisch Name:
RO-31-8220
Synonyma:
CS-1132;RO-31-8220;Ro31-8220MsOH;Ro 31-8220 Mesylat;Ro 31-8220/Ro318220;RO-31-8220 USP/EP/BP;BisindolylMaleiMide IX Mesylate;BISINDOLYLMALEIMIDE IX, METHANESULFONATE;Ro-31-8220 - CAS 138489-18-6 - Calbiochem;Bisindolylmaleimide IX (Ro 31-8220 Mesylate)
CBNumber:
CB9711637
Summenformel:
C25H23N5O2S
Molgewicht:
457.55
MOL-Datei:
138489-18-6.mol
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RO-31-8220 Eigenschaften

storage temp. 
2-8°C
Löslichkeit
DMSO:52.77(Max Conc. mg/mL);95.31(Max Conc. mM)
DMF:25.0(Max Conc. mg/mL);45.15(Max Conc. mM)
DMF:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.18(Max Conc. mM)
Ethanol:2.77(Max Conc. mg/mL);5.0(Max Conc. mM)
Aggregatzustand
Red solid
Farbe
Red

Sicherheit

HS Code  2933790090

RO-31-8220 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Ro 31-8220 Mesylate is a protein kinase C (PKC) inhibitor.

Allgemeine Beschreibung

Ro 31-8220 is a bisindolylmaleimide derivative of staurosporine. Ro 31-8220 blocks MAP kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression and stimulates Jun N-terminal Kinase (JNK1). It has immunosuppressive properties.

Biochem/physiol Actions

Inhibitor of GRK-5 (G protein-coupled receptor kinase); PKC (protein kinase C); MAPKAP kinase 1β and p70 S6 kinase.

RO-31-8220 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

RO-31-8220 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 132)Lieferanten
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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 ada@ipurechemical.com CHINA 3465 58
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InvivoChem 		+1-708-310-1919 +1-13798911105
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ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58

138489-18-6()Verwandte Suche:

2-Aminooctadec-4-en-1,3-diol
  • RO-31-8220
  • BISINDOLYLMALEIMIDE IX, METHANESULFONATE
  • 3-[1-[3-(AMIDINOTHIO)PROPYL-1H-INDOL-3-YL]-3-(1-METHYL-1H-INDOL-3-YL)MALEIMIDE
  • BISINDOLYLMALEIMIDE IX METHANESULPHONATE SALT
  • BisindolylMaleiMide IX Mesylate
  • BisindolylMaleiMide IX . Methansulfonate [Ro 31-8220]
  • Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, methanesulfonate (1:1)
  • Ro31-8220MsOH
  • Ro 31-8220 Mesylat
  • Ro 31-8220/Ro318220
  • Ro-31-8220 - CAS 138489-18-6 - Calbiochem
  • 3-[3-[2,5-Dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl carbamimidothioic acid ester mesylate
  • RO 31-8220 METHANESULFONATE; BISINDOLYLMALEIMIDE IX MESYLATE;RO318220
  • CS-1132
  • Bisindolylmaleimide IX (Ro 31-8220 Mesylate)
  • RO-31-8220 USP/EP/BP
  • 3-(3-(4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-1H-indol-1-yl)propyl carbamimidothioate
  • 138489-18-6
  • C25H23N5O2SCH4O3S
  • C25H23N5O2S
  • C26H27N5O5S2
  • Smad
  • TGF-beta
  • Inhibitors
  • TGF-beta/Smad
  • inhibitor
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