(S)-1-N-Boc-2-methylpiperazine

169447-70-5

CAS-Nr.: 169447-70-5

Englisch Name:: (S)-1-N-Boc-2-methylpiperazine

Synonyma:: tert-butyl (S)-2-methylpiperazine-1-carboxylate;(R)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-1-Boc-2-methl-piperazine;(S)-N-Boc-2-methylpiperazine;(R)-2-METHYL-1-BOC-PIPERAZINE;(S)-1-Boc-2-methyl-piperazine;(S)-N1-BOC-2-METHYLPIPERAZINE;1-Boc-2-(S)-Methyl Piperazine;(S)-1-N-BOC-2-METHYL PIPERAZINE

CBNumber:: CB9714476

Summenformel:: C10H20N2O2

Molgewicht:: 200.28

MOL-Datei:: 169447-70-5.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 254

(S)-1-N-Boc-2-methylpiperazine Eigenschaften

Schmelzpunkt:: 43.0 to 47.0 °C

Siedepunkt:: 268.7±15.0 °C(Predicted)

Dichte: 0.997±0.06 g/cm3(Predicted)

storage temp.: Keep in dark place,Sealed in dry,Room Temperature

Löslichkeit: soluble in Methanol

Aggregatzustand: powder to crystal

pka: 8.49±0.40(Predicted)

Farbe: White to Almost white

InChI: InChI=1S/C10H20N2O2/c1-8-7-11-5-6-12(8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1

InChIKey: DATRVIMZZZVHMP-QMMMGPOBSA-N

SMILES: N1(C(OC(C)(C)C)=O)CCNC[C@@H]1C

CAS Datenbank: 169447-70-5(CAS DataBase Reference)

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

RIDADR	UN3077
HS Code	2933599590

Bildanzeige (GHS)

Alarmwort

Achtung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H314	Verursacht schwere Verätzungen der Haut und schwere Augenschäden.	Ätzwirkung auf die Haut	Kategorie 1B	Achtung		P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501

Sicherheit

P260	Dampf/Aerosol/Nebel nicht einatmen.
P271	Nur im Freien oder in gut belüfteten Räumen verwenden.

(S)-1-N-Boc-2-methylpiperazine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(S)-1-N-Boc-2-methylpiperazine is used in the preparation of pyrazolo[3,4-b]pyridine dual pharmacophores as PDE4-muscarinic antagonists.

Synthese

A solution of (S)-2-methyl piperazine (2 g, 20 mmol) in THF (200 ml_) was mixed with nBuLi (25 ml, 1.6 M in hexanes, 40 mmol) at rt. The solution was stirred for 30 minutes before TBDMSCI (3.04 g, 20 mmol) was added. The mixture was stirred for 1 hour and then (Boc)2O (5.2 g, 24 mmol) was added to the solution. After 1 hour, the solution was diluted with H2O (50 ml). The organic layer was separated, washed with brine (50 mL), dried over Na2SO4, and concentrated EPO under vacuum. Finally, (S)-1-N-Boc-2-methylpiperazine was obtained after purification.

(S)-1-N-Boc-2-methylpiperazine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

(S)-1-BENZYL-3-METHYLPIPERAZINE-2,5-DIONE (S)-TERT-BUTYL 4-BENZYL-2-METHYLPIPERAZINE-1-CARBOXYLATE (S)-METHYL 2-(2-CHLOROACETAMIDO) PROPANOATE 2-(S)-METHYLPIPERAZINE-1,4-DICARBOXYLIC ACID 4-BENZYL ESTER 1-TER-BUTYL ESTER (S)-(+)-2-Methylpiperazine (S)-2-METHYL-4-BENZYLPIPERAZINE

Downstream Produkte

FVQORRADVAYZAV-AWEZNQCLSA-N

(S)-1-N-Boc-2-methylpiperazine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 254)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Boc Chemical Co., Ltd.	021-34975602; +8618721111801	shangli@bocchem.com	China	138	58
Purest Pharmaceuticl （Xi’an) Co,.LTD	+8613893405577	12829054@qq.com	China	74	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	6711	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	724	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	7836	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58

169447-70-5()Verwandte Suche:

tert-Butylperbenzoat 1-Methylpiperazin 1-Methyl-2-pyrrolidon 1,2-Dimethylhydrazin-dihydrochlorid N-(Hydroxymethyl)acrylamid 2-Methylpiperazin Diisobutylphthalat 1-Benzhydrylpiperazin Butyl-4-hydroxybenzoat 1-Methylimidazol 2,2'-Methyliminodiethanol N-Methylacetamid Isobutylchlorformiat

(R)-2-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
(R)-2-METHYL-1-BOC-PIPERAZINE
(S)-1-N-BOC-2-METHYL PIPERAZINE
(S)-2-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
(S)-1-Boc-2-methyl-piperazine
Tert-Butyl2(S)-methylpiperazine-1-carboxylate
2-S-Methyl-piperazine-1-carboxylic acid tert-butyl ester
(S)-1-N-Boc-2-Methylpiperizine tert-butyl 2(S)-methylpiperazine-1-carboxylate
(S)-N1-BOC-2-METHYLPIPERAZINE
(S)-1-Boc-2-methl-piperazine
(S)-1-N-Boc-2-Methylpiperazine ,98%
(2S)-2-Methylpiperazine, N1-BOC protected 98%
tert-Butyl (2S)-2-methylpiperazine-1-carboxylate (2S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine
(2S)-2-Methyl-1-piperazinecarboxylic Acid 1,1-DiMethylethyl Ester
tert-Butyl (2S)-2-Methylpiperazine-1-carboxylate
1-Piperazinecarboxylic acid, 2-methyl-, 1,1-dimethylethyl ester, (2S)-
(S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine
(2S)-2-Methylpiperazine,N1-BOCprotected98%
(S)-N-Boc-2-methylpiperazine
(S)-N-Boc-2-methylpiperazine,98%e.e.
(S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine
1-Boc-2-(S)-Methyl Piperazine
TERT-BUTYL (2S)-2-METHYPIPERAZINE-1-CARBOXYLATE
(S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine >
tert-Butyl (S)-2-Methyl-1-piperazinecarboxylate
(S)-2-Methyl-1-piperazinecarboxylic Acid tert-Butyl Ester
(S)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE
(R)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE
tert-butyl (S)-2-methylpiperazine-1-carboxylate
169447-70-5
170033-47-4
Chiral Reagents
Heterocycles
pharmacetical
Piperaizine