Granisetron Hydrochloride
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- CAS-Nr.
- 107007-99-8
- Englisch Name:
- Granisetron Hydrochloride
- Synonyma:
- GRANISETRON HYDROCHLORIDE;GRANISETRON HCL;KYTRIL;1-Methyl-N-[(1β,3α,5β)-9-methyl-9-azabicyclo[3.3.1]nonane-3-yl]-1H-indazole-3-carboxamide·hydrochloride;Kitryl;BRL-43694A;Gransetron HCl;GranisetronBase;midehydrochloride;GranisetronHclFda
- CBNumber:
- CB9728851
- Summenformel:
- C18H25ClN4O
- Molgewicht:
- 348.87
- MOL-Datei:
- 107007-99-8.mol
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Granisetron Hydrochloride Eigenschaften
- Schmelzpunkt:
- 290-292°C
- storage temp.
- Room temp
- Löslichkeit
- H2O: >10mg/mL
- Aggregatzustand
- solid
- Farbe
- white to off-white
- Merck
- 14,4536
- CAS Datenbank
- 107007-99-8(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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Granisetron Hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R62:Kann möglicherweise die Fortpflanzungsfähigkeit beeinträchtigen.
R37/38:Reizt die Atmungsorgane und die Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R36:Reizt die Augen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37:Geeignete Schutzhandschuhe tragen.
Beschreibung
Granisetron hydrochloride is the second selective 5HT
-3-antagonist approved for the
management of nausea and vomiting induced by cancer chemotherapy.Like
ondansetron, granisetron hydrochloride is superior to metoclopramide in both efficacy
and side effect profile. The compound appears to be effective both as a prophylactic
agent and in blocking vomiting once started.
Chemische Eigenschaften
White to Off-White Crystalline Sold
Verwenden
A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemothera
py. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarini
c receptor
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Biologische Aktivität
5-HT 3 receptor antagonist that possesses potent antiemetic activity.
Granisetron Hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Granisetron Hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 597)Lieferanten
107007-99-8()Verwandte Suche:
N,N-Dimethylformamid
Granisetron
ALOSETRON
(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one monohydrochloride
Formamid
Methylacetat
Formamide,Deionized
CHLOANTRANILIPROLE
Kresoxim-methyl
Benzamid
Topotecan hydrochloride
Methylsalicylat
Tribenuron methyl
Thiophanat-methyl
2-[[[[(4-Methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]amino]sulfonyl]benzoic acid methyl ester
(2alpha,6alpha,8alpha,9abeta)-Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl-1H-indole-3-carboxylate
Milrinon
Methyl
- 1-methyl-n-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-1h-indazole-3-carboxamid
- endo-1-methyl-n-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-1h-indazole-3-carboxa
- endo-monohydrochlorid
- midehydrochloride
- 1-METHYL-N-[(3-ENDO)-9-METHYL-9-AZABICYCLO[3.3.1]NON-3-YL]-1H-INDAZOLE-3-CARBOXAMIDE HYDROCHLORIDE
- 1-Methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-isoindole-3-carboxamide hydrochloride
- 1-Methyl-N-[(1β,5β)-9-methyl-9-azabicyclo[3.3.1]nonane-3α-yl]-1H-indazole-3-carboxamide·hydrochloride
- Kitryl
- Granisetron Hydrochloride, EP
- Granisetron hydrochloride COS
- Granisetron hydrochloride(BRL 43694)
- Granisetron Hydrochloride (150 mg)
- Granisetron dydrochloride
- 1-methyl-N-(9-methyl-9-aza-bicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide hydrochloride
- Granisetron hydrochloride
1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride
- 1-Methyl-N-((1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide hydrochl
- BRL-43694A
- GRANISERTROL HYDROCHLORIDE
- GRANISTRON HYDROCHLORIDE
- GranisetronHclFda
- GranisetronBase
- GranisetronHydrochlorideFdaInspected
- Granisertronhydrochloride
- Granisetron hydrocholride
- BRL-43694A, Kytril, 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide Hydrochloride
- 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-, monohydrochloride, endo-
- 1H-Indazole-3-carboxamide, 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, monohydrochloride
- endo-monohydrochloride
- Gransetron HCl
- GRANISTERON HYDROCHLORIDE
- 1-METHYL-N-(9-METHYL-9-AZABICYCLO[3.3.1]NON-3-YL)-INDAZOLE-3-CARBOXAMIDE HCL
- 1-Methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-
- 1-METHYL-1H-INDAZOLE-3-CARBOXYLIC ACID (9-METHYL-9-AZA-BICYCLO[3.3.1]NON-3-YL)-AMIDE: HYDROCHLORIDE
- endo-1-Methyl-N-(9-methyl-9-azabicyclo[3．3．1]non-3-y1)-1H-indazole-3-carboxamide hydrochloride
- Granisetron hydrochloride CRS
- GranisetronHydrochloride>
- 1-Methylindazole-3-carboxylic acid USP/EP/BP
- Granisetron hydrochloride salt
- Granisetron Hydrochloride/1-Methylindazole-3-carboxylic acid
- Granisetron hydrochl
- Granisetron HCl (BRL 43694A)
- Granisetron HydrochlorideQ: What is
Granisetron Hydrochloride Q: What is the CAS Number of
Granisetron Hydrochloride Q: What is the storage condition of
Granisetron Hydrochloride Q: What are the applications of
Granisetron Hydrochloride
- Granisetron Hydrochloride (1298106)
- Granisetron hydrochloride, 98%, a serotonin 5-HT3 receptor antagonist
- 1-Methyl-N-[(1β,3α,5β)-9-methyl-9-azabicyclo[3.3.1]nonane-3-yl]-1H-indazole-3-carboxamide·hydrochloride
- KYTRIL
- GRANISETRON HCL
- GRANISETRON HYDROCHLORIDE
- GranisetronHydrochloride/BRL43694A
- 107007-99-8
- 156-2-21
- C18H24N4OxHCl
- C18H24N4OClH
- C18H24N4OHClC18H25ClN4O
- C18H25ClN4O
- C18H24N4OHCl
- Other APIs
- Digestive System
