Esomeprazole magnesium trihydrate
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- CAS-Nr.
- 217087-09-7
- Englisch Name:
- Esomeprazole magnesium trihydrate
- Synonyma:
- Nexium;EsomepazoleTrihydrate;Esomeprazole Mg Trihydrate;ESOPMEPRAZOLE MG TRIHYDRATE;EsoMeprazole Meg. Trihydrate;Omeprazole 8.5%/12.5% pellels;Esomeprazole Magnesium (10 mg);Esomeprazole Magnesium (25 mg);Omeprazole Magnesium Trihydrate;EsoMeprazole Magnesiu Trihydrate
- CBNumber:
- CB9740619
- Summenformel:
- C34H38MgN6O7S2
- Molgewicht:
- 731.14
- MOL-Datei:
- 217087-09-7.mol
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Esomeprazole magnesium trihydrate Eigenschaften
- Schmelzpunkt:
- 184-189°C (dec.)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- Löslichkeit
- Slightly soluble in water, soluble in methanol, practically insoluble in heptane.
- InChI
- InChI=1S/2C17H18N3O3S.Mg.H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;/h2*5-8H,9H2,1-4H3;;1H2/q2*-1;+2;
- InChIKey
- VEVZQDGATGBLIC-UHFFFAOYSA-N
- SMILES
- C(C1N=CC(C)=C(OC)C=1C)S1C2[N-]C3=CC(OC)=CC=C3N=2[Mg+2]2(O=S(CC3N=CC(C)=C(OC)C=3C)C3[N-]C4=CC(OC)=CC=C4N2=3)O=1.O
- CAS Datenbank
- 217087-09-7(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
22 |
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| WGK Germany |
3 |
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| HS Code |
2933399090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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Esomeprazole magnesium trihydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Off-White Powder
Verwenden
esomeprazole magnesium trihydrate for the healing of peptic ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
- Zollinger-Ellison syndrome
- Peptic ulcer, site unspecified
- Duodenal ulcer
- Gastric ulcer
- Gastro-oesophageal reflux disease
Esomeprazole belongs to the family of medications known as proton pump inhibitors (PPIs). Esomeprazole is registered by the Therapeutic Goods Administration (TGA) for the following indications:
- Gastro-Oesophageal Reflux Disease (GORD):
- treatment of erosive reflux oesophagitis;
- long-term management of patients with healed oesophagitis to prevent relapse;
- symptomatic treatment of gastro-oesophageal reflux disease (GORD).
In combination with appropriate antibiotics for:
- healing of duodenal ulcer associated with Helicobacter pylori;
- eradication of Helicobacter pylori in patients with active or healed peptic ulcer.
- Short-term treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) (non-selective and COX-2 selective) therapy.
- Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
- Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy in patients at risk.
Trademarks
Nexium (AstraZeneca).
Biologische Aktivität
Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent, orally active H+, K+-ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research. Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release by inhibiting V-H+-ATPases.
Esomeprazole magnesium trihydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Esomeprazole magnesium trihydrate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 414)Lieferanten
217087-09-7()Verwandte Suche:
- ESOMEPRAZOLE MAGNESIUM TRIHYDRATE
- bis(5-methoxy-2-[(s)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1h-benzylimidazole-1-yl) magnesium trihydrate
- (T-4)-Bis[5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]magnesium
- Nexium
- ESOPMEPRAZOLE MG TRIHYDRATE
- 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]benzimidazol-1-ide
- 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
- 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
- EsoMeprazole Meg. Trihydrate
- Esomeprazole Magnesium (10 mg)
- ESOMEPRAZOLE MAGNESIUM TRIHYDRATE USP
- (S)-OMeprazole MagnesiuM trihydrate
- MagnesiuM,bis[6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl-kO]-1H-benziMidazolato-kN3]-, hydrate (1:3), (T-4)-
- Esomeprazole magnesium trihydrate
Bis(5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzylimidazole-1-yl) magnesium trihydrate
- Esomeprazole Magnesium (25 mg)
- EsoMeprazole Magnesiu Trihydrate
- Esomeprazole magnesium thihydrate
- Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-, hydrate (1:3), (T-4)-
- Esomeprazole Magnesium Dihydrate/Trihydrate
- Magnesium,bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-kO]-1H-benzimidazolato-kN3]-, hydrate
- Esomeprazole agnesium trihydrate
- Omeprazole Magnesium Trihydrate
- Esomeprazole magnesium trihydrate CRS
- Nesomeprazole magnesium trihydrate
- EsomepazoleTrihydrate
- Esomeprazole Magnesium (1249789)
- Omeprazole(Esomeprazole Magnesium) Trihydrate
- Esomeprazole Magnesium Tri-Hydrate IP/Ph. Eur./BP
- Omeprazole 8.5%/12.5% pellels
- Esomeprzole magnesium Trihydrate
- Esomperazole Magnessium Trihydrate
- Esomeprazole Mg Trihydrate
- 217087-09-7
- 2C17H18N3O3SMg3H2O
- C34H36MgN6O6S23H2O
- C34H42MgN6O9S2
- 71312
- Acid pump inhibitors
- Chiral Reagents
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
