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Dinatriumdisulfit Produkt Beschreibung

Sodium metabisulfite Struktur
7681-57-4
CAS-Nr.
7681-57-4
Bezeichnung:
Dinatriumdisulfit
Englisch Name:
Sodium metabisulfite
Synonyma:
E223;fertisilo;Sodium disulphite;SodiuM pyrosulfit;Sodium pyrosulfite;Sodiummetabisufite;Sodium dissulfite ;Disodium disulphite;Sodium pyrosulphite;Sodiummetadisulfite
CBNumber:
CB9854280
Summenformel:
2Na.O5S2
Molgewicht:
190.11
MOL-Datei:
7681-57-4.mol

Dinatriumdisulfit Eigenschaften

Schmelzpunkt:
150 °C
Dichte
1.48
storage temp. 
Store at RT.
Löslichkeit
540 g/L (20°C)
Aggregatzustand
Powder/Solid
Wichte
1.48
Farbe
White to slightly yellow
PH
3.5-5 (50g/l, H2O, 20℃)
Wasserlöslichkeit
540 g/L (20 ºC)
Sensitive 
Air & Moisture Sensitive
Merck 
14,8638
Stabilität:
Stable. Incompatible with strong oxidizing agents, strong acids. Contact with strong acids releases a poisonous gas. May be moisture and air sensitive.
InChIKey
HRZFUMHJMZEROT-UHFFFAOYSA-L
CAS Datenbank
7681-57-4(CAS DataBase Reference)
EPA chemische Informationen
Sodium metabisulfite (7681-57-4)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn,Xi
R-Sätze: 22-31-41-36/37/38-52
S-Sätze: 26-39-46-36-16
RIDADR  3260
WGK Germany  1
RTECS-Nr. UX8225000
TSCA  Yes
HSCode  2832 10 00
PackingGroup  III
Giftige Stoffe Daten 7681-57-4(Hazardous Substances Data)
Toxizität LD50 orally in Rabbit: 1540 mg/kg LD50 dermal Rat > 2000 mg/kg
Bildanzeige (GHS)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H318 Verursacht schwere Augenschäden. Schwere Augenschädigung Kategorie 1 Achtung P280, P305+P351+P338, P310
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Dinatriumdisulfit Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD

WEISSES PULVER

CHEMISCHE GEFAHREN

Zersetzung beim Erhitzen unter Bildung von Schwefeloxiden. Starkes Reduktionsmittel. Reagiert mit Oxidationsmitteln. Reagiert sehr heftig mitkonzentrierter Natriumnitritlösung. Zersetzung bei Kontakt mit Säuren unter Bildung von Schwefeloxiden.

ARBEITSPLATZGRENZWERTE

TLV: 5 mg/m?(als TWA); Krebskategorie A4 (nicht klassifizierbar als krebserzeugend für den Menschen); (ACGIH 2005).

AUFNAHMEWEGE

Aufnahme in den Körper durch Inhalation und durch Verschlucken.

INHALATIONSGEFAHREN

Verdampfung bei 20°C vernachlässigbar; eine gesundheitsschädliche Partikelkonzentration in der Luft kann jedoch beim Dispergieren schnell erreicht werden.

WIRKUNGEN BEI KURZZEITEXPOSITION

WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt die Augen, die Atemwege und reizt stark den Magen-Darm-Trakt. Inhalation kann zu Asthma führen.

LECKAGE

NICHT mit Sägemehl oder anderen brennbaren Absorptionsmitteln binden. Verschüttetes Material in Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Persönliche Schutzausrüstung: Atemschutzgerät, P2-Filter für schädliche Partikel. NICHT in die Umwelt gelangen lassen.

R-Sätze Betriebsanweisung:

R22:Gesundheitsschädlich beim Verschlucken.
R31:Entwickelt bei Berührung mit Säure giftige Gase.
R41:Gefahr ernster Augenschäden.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
S46:Bei Verschlucken sofort ärztlichen Rat einholen und Verpackung oder Etikett vorzeigen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Aussehen Eigenschaften

Na2O5S2; Natriummetabisulfit, Natriumpyrosulfit, Pyrosulfit, Disulfit. Farbloser Feststoff mit charakteristischem Geruch.

Gefahren für Mensch und Umwelt

Gesundheitsschädlich beim Verschlucken. Gefahr ernster Augenschäden. Reizt die Atmungsorgane.
Nicht mit Säuren oder Oxidationsmitteln in Berührung bringen.
Setzt bei der Zersetzung Schwefeldioxid frei.
Entwickelt bei Berührung mit Säure giftige Gase.
LD50 (i.v., Ratte) 115 mg/kg.

Schutzmaßnahmen und Verhaltensregeln

Schutzhandschuhe als kurzzeitiger Staubschutz.

Verhalten im Gefahrfall

Persönliche Maßnahmen: Substanzkontakt vermeiden.
Vorsichtig trocken aufnehmen. Der Entsorgung zuführen. Nachreinigen.
Auf Umgebung abstimmen.
Im Brandfall können Schwefeloxide freigesetzt werden.

Erste Hilfe

Nach Hautkontakt: Mit reichlich Wasser abwaschen.
Nach Augenkontakt: Mit reichlich Wasser bei geöffnetem Lidspalt mindestens 15 Minuten ausspülen. Sofort Augenarzt hinzuziehen.
Nach Einatmen: Frischluft. Arzt hinzuziehen.
Nach Verschlucken: Reichlich Wasser trinken. Erbrechen auslösen. Arzt hinzuziehen.
Nach Kleidungskontakt: Kontaminierte Kleidung entfernen.
Ersthelfer: siehe gesonderten Anschlag

Sachgerechte Entsorgung

Gelöst in Wasser zu den neutralen, wässrigen Lösemittelabfällen geben.

Chemische Eigenschaften

white crystalline powder with a sulfur smell

Chemische Eigenschaften

Sodium metabisulfite is a white crystalline powder. Sulfur dioxide odor. It may be considered the anhydride of 2 molecules of sodium disulfite.

Chemische Eigenschaften

Sodium metabisulfite occurs as colorless, prismatic crystals or as a white to creamy-white crystalline powder that has the odor of sulfur dioxide and an acidic, saline taste. Sodium metabisulfite crystallizes from cold water as a hydrate containing seven water molecules.

Verwenden

Sodium Metabisulfite is a preservative and antioxidant that exists as crystals or powder having a sulfur dioxide odor. it is readily solu- ble in water. it is used in dried fruits to preserve flavor, color, and to inhibit undesirable microorganism growth. it prevents “black spots” due to oxidative deterioration in shrimp. it is used in maraschino cherries. it is found in lemon drinks as a preservative. see sulfur dioxide.

Verwenden

Pharmaceutic aid (antioxidant).

Verwenden

sodium metabisulfite is an anti-oxidant and reducing agent.

Vorbereitung Methode

Sodium metabisulfite is prepared by saturating a solution of sodium hydroxide with sulfur dioxide and allowing crystallization to occur; hydrogen is passed through the solution to exclude air. Sodium metabisulfite may also be prepared by saturating a solution of sodium carbonate with sulfur dioxide and allowing crystallization to occur, or by thermally dehydrating sodium bisulfite.

Definition

ChEBI: An inorganic sodium salt composed of sodium and disulfite ions in a 2:1 ratio.

Hazard

Toxic by inhalation. Upper respiratory tract irritant. Questionable carcinogen.

Pharmazeutische Anwendungen

Sodium metabisulfite is used as an antioxidant in oral, parenteral, and topical pharmaceutical formulations, at concentrations of 0.01–1.0% w/v, and at a concentration of approximately 27% w/v in intramuscular injection preparations. Primarily, sodium metabisulfite is used in acidic preparations; for alkaline preparations, sodium sulfite is usually preferred. Sodium metabisulfite also has some antimicrobial activity, which is greatest at acid pH, and may be used as a preservative in oral preparations such as syrups.
In the food industry and in wine production, sodium metabisulfite is similarly used as an antioxidant, antimicrobial preservative, and antibrowning agent. However, at concentrations above about 550 ppm it imparts a noticeable flavor to preparations. Sodium metabisulfite usually contains small amounts of sodium sulfite and sodium sulfate.

Kontakt-Allergie

This agent is frequently used as a preservative in pharmaceutical products, in the bread-making industry as an antioxidant, and it can induce contact dermatitis. It can be used as a reducing agent in photography and caused dermatitis in a photographic technician, probably acting as an aggravating irritative factor. Sodium metabisulfite contains a certain amount of sodium sulfite and sodium sulfate.

Sicherheitsprofil

An inhalation hazard. Poison by intravenous route. Moderately toxic by parenteral route. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and Na2O.

Sicherheit(Safety)

Sodium metabisulfite is widely used as an antioxidant in oral, topical, and parenteral pharmaceutical formulations; it is also widely used in food products.
Although it is extensively used in a variety of preparations, sodium metabisulfite and other sulfites have been associated with a number of severe to fatal adverse reactions. These are usually hypersensitivity-type reactions and include bronchospasm and anaphylaxis. Allergy to sulfite antioxidants is estimated to occur in 5–10% of asthmatics, although adverse reactions may also occur in nonasthmatics with no history of allergy.
Following oral ingestion, sodium metabisulfite is oxidized to sulfate and is excreted in urine. Ingestion may result in gastric irritation, owing to the liberation of sulfurous acid, while ingestion of large amounts of sodium metabisulfite can cause colic, diarrhea, circulatory disturbances, CNS depression, and death.
In Europe, the acceptable daily intake of sodium metabisulfite and other sulfites used in foodstuffs has been set at up to 3.5 mg/kg body-weight, calculated as sulfur dioxide (SO2). The WHO has similarly also set an acceptable daily intake of sodium metabisulfite, and other sulfites, at up to 7.0 mg/kg body-weight, calculated as sulfur dioxide (SO2).
LD50 (rat, IV): 0.12 g/kg

mögliche Exposition

Sodium metabisulfite is used as an antioxidant in pharmaceutical preparations and as a preservative in foods. People with asthma have a greater chance of having an allergic reaction with this chemical. Individuals allergic to sodium bisulfite (a food preservative found in some wine, fresh shrimp; packaged foods; and restaurant salads and potatoes) may have a severe reaction when exposed to sodium metabisulfite.

Lager

On exposure to air and moisture, sodium metabisulfite is slowly oxidized to sodium sulfate with disintegration of the crystals. Addition of strong acids to the solid liberates sulfur dioxide.
In water, sodium metabisulfite is immediately converted to sodium (Na+) and bisulfite (HSO3-) ions. Aqueous sodium metabisulfite solutions also decompose in air, especially on heating. Solutions that are to be sterilized by autoclaving should be filled into containers in which the air has been replaced with an inert gas, such as nitrogen. The addition of dextrose to aqueous sodium metabisulfite solutions results in a decrease in the stability of the metabisulfite.
The bulk material should be stored in a well-closed container, protected from light, in a cool, dry place.

Versand/Shipping

UN1759 Corrosive solids, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, Technical Name required. UN2693 Bisulfites, inorganic, aqueous solutions, n.o.s., Hazard class: 8; Labels: 8-Corrosive material.

Inkompatibilitäten

Sodium metabisulfite reacts with sympathomimetics and other drugs that are ortho- or para-hydroxybenzyl alcohol derivatives to form sulfonic acid derivatives possessing little or no pharmacological activity. The most important drugs subject to this inactivation are epinephrine (adrenaline) and its derivatives. In addition, sodium metabisulfite is incompatible with chloramphenicol owing to a more complex reaction; it also inactivates cisplatin in solution.
It is incompatible with phenylmercuric acetate when autoclaved in eye drop preparations.
Sodium metabisulfite may react with the rubber caps of multidose vials, which should therefore be pretreated with sodium metabisulfite solution.

Inkompatibilitäten

A strong reducing agent. Keep away from oxidizers. Mixtures with water forms a strong corrosive. Contact with acids releases toxic fumes. Heat causes decomposition. Slowly oxidized to the sulfate on exposure to air and moisture. Attacks metals

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (epidural;inhalation; IM and IV injections; ophthalmic solutions; oral preparations; rectal, topical, and vaginal preparations). Included in nonparenteral and parenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Dinatriumdisulfit Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dinatriumdisulfit Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 412)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1878 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21686 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22633 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32447 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29996 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23981 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8814 58
Cangzhou Wanyou New Material Technology Co.,Ltd
18631714998
sales@czwytech.com CHINA 915 58

7681-57-4(Dinatriumdisulfit)Verwandte Suche:


  • SODIUM META-BISULFITE GRAN
  • Sodiummetabisulfite,ACS,97%min
  • Sodium metabisulfite, anhydrous, extra pure, 97%
  • Sodium metabisulfite, for analysis ACS, 97+%
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  • SODIUMMETABISULFITE,GRANULAR,NF,EP,BP,JP
  • Sodiummetadisulfite
  • NATRIUMPYROSULFIT (NATRIUMDISULFIT)
  • Disodium disulphite
  • Disulfurous acid disodium salt
  • Pyrosulfurous acid disodium salt
  • Sodium metabisulfite
  • Sodium pyrosulfite
  • Sodium metabisulfite, SO2 58.5% min
  • SODIUM METABISULFITE GRANULAR
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  • Sodium Metabisulfite, Meets analytical specification of Ph. Eur.BP, NF, FCC
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