2-Amino-4-methyl-5-bromopyrimidine
- CAS No.
- 17321-93-6
- Chemical Name:
- 2-Amino-4-methyl-5-bromopyrimidine
- Synonyms
- 100704;5-Bromo-4-methyl-2-pyrimidinamine;2-PyriMidinaMine,5-broMo-4-Methyl-;2-Amino-5-bromo-4-methylpyrimidine;2-amino-4-methyl-5-bromopyrimidine;5-Bromo-4-methyl-2-aminopyrimidine;5-Bromo-2-amino-4-methylpyrimidine;5-BROMO-4-METHYL-PYRIMIDIN-2-YLAMINE;5-bromo-4-methylpyrimidine-2-ylamine;2-AMino-5-broMo-4-MethylpyriMidine 97%
- CBNumber:
- CB01010770
- Molecular Formula:
- C5H6BrN3
- Molecular Weight:
- 188.03
- MDL Number:
- MFCD00094469
- MOL File:
- 17321-93-6.mol
- MSDS File:
- SDS
| Melting point | 192-194℃ |
|---|---|
| Boiling point | 345.4±34.0 °C(Predicted) |
| Density | 1.699±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | solid |
| pka | 2.47±0.10(Predicted) |
| Appearance | White to light yellow Solid |
| InChI | InChI=1S/C5H6BrN3/c1-3-4(6)2-8-5(7)9-3/h2H,1H3,(H2,7,8,9) |
| InChIKey | LPQVTZJEIXYDQA-UHFFFAOYSA-N |
| SMILES | C1(N)=NC=C(Br)C(C)=N1 |
| CAS DataBase Reference | 17321-93-6 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-37/38-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | N | |||||||||
| HS Code | 29335990 | |||||||||
| NFPA 704 |
|
2-Amino-4-methyl-5-bromopyrimidine price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 715085 | 2-Amino-5-bromo-4-methylpyrimidine 97% | 17321-93-6 | 1g | $68.8 | 2023-06-20 | Buy |
| Alfa Aesar | H54186 | 2-Amino-5-bromo-4-methylpyrimidine, 96% | 17321-93-6 | 1g | $35.8 | 2021-12-16 | Buy |
| Alfa Aesar | H54186 | 2-Amino-5-bromo-4-methylpyrimidine, 96% | 17321-93-6 | 5g | $134 | 2021-12-16 | Buy |
| Alfa Aesar | H54186 | 2-Amino-5-bromo-4-methylpyrimidine, 96% | 17321-93-6 | 25g | $560 | 2021-12-16 | Buy |
| TRC | A602188 | 2-Amino-5-bromo-4-methylpyrimidine | 17321-93-6 | 100mg | $60 | 2021-12-16 | Buy |
2-Amino-4-methyl-5-bromopyrimidine Chemical Properties,Uses,Production
Synthesis
108-52-1
17321-93-6
General procedure for the synthesis of 2-amino-4-methyl-5-bromopyrimidine from 2-amino-4-methylpyrimidine: To a solution of 4-methylpyrimidin-2-ylamine (10.9 g, 100 mmol) in chloroform (400 mL) was added N-bromosuccinimide (17.8 g, 100 mmol). The reaction mixture was stirred under light-avoiding conditions for 15 hours. Upon completion of the reaction, the mixture was transferred to dichloromethane (140 mL) and washed sequentially with 1N sodium hydroxide solution (3 x 200 mL) and saturated sodium chloride solution (100 mL). The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give 5-bromo-4-methylpyrimidin-2-ylamine (18.8 g, 99% yield). The product was detected by LCMS (m/z): 188.0/190.0 (MH+). 1H NMR (CDCl3) data: δ 8.22 (s, 1H), 5.02 (bs, 2H), 2.44 (s, 3H).
References
[1] Patent: WO2007/84786, 2007, A1. Location in patent: Page/Page column 91-92
[2] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 10, p. 774 - 779
[3] Patent: WO2011/130628, 2011, A1. Location in patent: Page/Page column 180
[4] Patent: US2013/102595, 2013, A1. Location in patent: Paragraph 0377; 0378
[5] Patent: JP2015/187145, 2015, A. Location in patent: Paragraph 0330
2-Amino-4-methyl-5-bromopyrimidine Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Liyang Kunlun Biological Technology Co., Ltd. | +86-13813530041 | z13813530041@126.com | China | 337 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49733 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
View Lastest Price from 2-Amino-4-methyl-5-bromopyrimidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-05-23 | 2-Amino-4-methyl-5-bromopyrimidine
17321-93-6
|
US $150.00 / kg | 1kg | 99% | 500kg | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2025-04-02 | 5-Bromo-4-methyl-pyrimidin-2-ylamine
17321-93-6
|
US $0.00-0.00 / kg | 50kg | 0.99 | 20 tons | Jiangsu Liyang Kunlun Biological Technology Co., Ltd. | |
 |
2022-04-22 | 2-Amino-5-bromo-4-methylpyrimidine
17321-93-6
|
US $0.00-0.00 / kg | 0.0001kg | 98%min | 100kgs/month | Shanghai Rlavie Technology Co ltd |
-
- 2-Amino-4-methyl-5-bromopyrimidine
17321-93-6
- US $150.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- 5-Bromo-4-methyl-pyrimidin-2-ylamine
17321-93-6
- US $0.00-0.00 / kg
- 0.99
- Jiangsu Liyang Kunlun Biological Technology Co., Ltd.
-
- 2-Amino-5-bromo-4-methylpyrimidine
17321-93-6
- US $0.00-0.00 / kg
- 98%min
- Shanghai Rlavie Technology Co ltd
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