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Fuzapladib sodium hydrate
- CAS No.
- 351999-87-6
- Chemical Name:
- Fuzapladib sodium hydrate
- Synonyms
- Fuzapladib sodium;IS-741 sodium monohydrate;{3-[(Cyclohexylcarbonyl)amino]-5-(trifluorométhyl)-2-pyridinyl}(éthylsulfonyl)azanide de sodium, hydrate (1:1:1);Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1)
- CBNumber:
- CB010340929
- Molecular Formula:
- C15H23F3N3NaO4S
- Molecular Weight:
- 421.41
- MDL Number:
- MOL File:
- 351999-87-6.mol
Last updated:2024-03-05 11:57:54
| InChI | InChI=1S/C15H20F3N3O3S.Na.H2O.H/c1-2-25(23,24)21-13-12(8-11(9-19-13)15(16,17)18)20-14(22)10-6-4-3-5-7-10;;;/h8-10H,2-7H2,1H3,(H,19,21)(H,20,22);;1H2; |
|---|---|
| InChIKey | QGYVDECYMSBHMK-UHFFFAOYSA-N |
| SMILES | N(C1C=C(C(F)(F)F)C=NC=1NS(=O)(=O)CC)C(C1CCCCC1)=O.[NaH].O |
| FDA UNII | 8D7CX8WO6Z |
Fuzapladib sodium hydrate Chemical Properties,Uses,Production
Description
Fuzapladib sodium hydrate, also known as N-[2-(Sodioethanesulfonamido)-5-(trifluoromethyl)pyridin-3-yl]cyclohexanecarboxamide monohydrate, is a phospholipase A2 ( PLA2) inhibitor and a leukocyte function-associated antigen-1 (LFA-1) activation inhibitor for the treatment of acute pancreatitis (AP) in animal species (dogs).
Uses
Fuzapladib Sodium Hydrate is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2).
Mechanism of action
Fuzapladib sodium hydrate controls the progression of pancreatitis by blocking the activation of adhesion molecules (integrins) expressed on the surface of inflammatory cells and preventing inflammatory cells from adhering to vascular endothelial cells and infiltrating tissues.
Fuzapladib sodium hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Fuzapladib sodium hydrate Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hpets Biotech Company (Chongqing) Co.,ltd | +8613340353813 | info@hanpets.com | China | 26 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.com | China | 24246 | 58 |
| Supplier | Advantage |
|---|---|
| Hpets Biotech Company (Chongqing) Co.,ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
View Lastest Price from Fuzapladib sodium hydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-02-27 | Fuzapladib sodium
351999-87-6
|
US $0.00 / kg | 1kg | 99% | 100 tons | Hpets Biotech Company (Chongqing) Co.,ltd |
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- Fuzapladib sodium
351999-87-6
- US $0.00 / kg
- 99%
- Hpets Biotech Company (Chongqing) Co.,ltd
Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1)
{3-[(Cyclohexylcarbonyl)amino]-5-(trifluorométhyl)-2-pyridinyl}(éthylsulfonyl)azanide de sodium, hydrate (1:1:1)
Fuzapladib sodium
IS-741 sodium monohydrate
351999-87-6
C15H23F3N3NaO4S