ChemicalBook >> CAS DataBase List >>Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1)

Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1)

Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1) structure

CAS No.: 2388506-43-0

Chemical Name:: Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1)

Synonyms: MAX-40279 hemifumarate;Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1)

CBNumber:: CB010688030

Molecular Formula:: C22H23FN6OS.1/2C4H4O4

Molecular Weight:: 993.12

MDL Number:

MOL File:: 2388506-43-0.mol

Last updated:2024-07-02 08:54:55

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Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1) Properties

storage temp.	-20°C, away from moisture
solubility	DMF : 1.96 mg/mL (3.53 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C)
form	Solid
color	Off-white to light yellow

Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1) Chemical Properties,Uses,Production

Biological Activity

MAX-40279 hemifumarate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemifumarate has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032)[1].

References

[1]. Yuguang Wang, et al. Novel Therapeutic Methods. Patent WO2021180032A1.

Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1) Preparation Products And Raw materials

Raw materials

Preparation Products

Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1) Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32836	60
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Chengdu PEIP Pharmaceutical Technology Co., LTD.	028-61715638 18011352545	1242335275@qq.com	China	416	58
Suzhou Haiben Pharmaceutical Co., Ltd	14760821013 14760821013	1816280386@qq.com	China	6752	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11977	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	021-59167510 18117107507	vip@med-life.cn	China	5012	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Aladdin Scientific	58
Chengdu PEIP Pharmaceutical Technology Co., LTD.	58
Suzhou Haiben Pharmaceutical Co., Ltd	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	58

MAX-40279 hemifumarate Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1) 2388506-43-0 C26H27FN6O5S