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ChicoricAcid

CAS No.
6537-80-0
Chemical Name:
ChicoricAcid
Synonyms
Chicoric;ChicoricAci;Chicoric acid;Purple daisies;Cichoric Acid (P);2,3-Dicaffeoyl-L-tartaric acid;CICHORIC ACID(P) )(AHP Verified);Dicaffeoyltartaric acid CICHORIENSAURE;Chicoric acid, 98%, from Echinacea purpurea (L.) Moench;2-O,3-O-Bis[3-(3,4-dihydroxyphenyl)propenoyl]-L-tartaric acid
CBNumber:
CB01075203
Molecular Formula:
C22H18O12
Molecular Weight:
474.37
MDL Number:
MFCD00189418
MOL File:
6537-80-0.mol
Last updated:2023-05-25 18:00:55

ChicoricAcid Properties

Melting point 200~208℃
Boiling point 785.0±60.0 °C(Predicted)
Density 1.641±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
form Solid
pka 1.47±0.25(Predicted)
color Pale Yellow
Water Solubility Water : 100 mg/mL (210.81 mM; Need ultrasonic)
Stability Hygroscopic
InChIKey YDDGKXBLOXEEMN-IABMMNSOSA-N
LogP 3.090 (est)
CAS DataBase Reference 6537-80-0
FDA UNII S4YY3V8YHD

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H317-H334
Precautionary statements  P261-P280-P284-P301+P312+P330-P304+P340-P342+P311
Hazard Codes  Xn
Risk Statements  22-42/43
Safety Statements  22-36/37-45
WGK Germany  3
HS Code  29182900

ChicoricAcid price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C7243 Chicoric Acid ≥95% (HPLC) 6537-80-0 10mg $126 2024-03-01 Buy
Sigma-Aldrich 1105315 Chicoric Acid United States Pharmacopeia (USP) Reference Standard 6537-80-0 20mg $1060 2024-03-01 Buy
Sigma-Aldrich C7243 Chicoric Acid ≥95% (HPLC) 6537-80-0 50mg $591 2024-03-01 Buy
TRC C291970 Chicoric Acid 6537-80-0 250mg $1210 2021-12-16 Buy
Usbiological 300068 Chicoric acid 6537-80-0 20mg $390 2021-12-16 Buy
Product number Packaging Price Buy
C7243 10mg $126 Buy
1105315 20mg $1060 Buy
C7243 50mg $591 Buy
C291970 250mg $1210 Buy
300068 20mg $390 Buy

ChicoricAcid Chemical Properties,Uses,Production

Chicory extract

Cicory acid is a water-soluble phenolic acid compound extracted from the dry whole grass of the Compositae.It is anti-inflammatory, can enhance immune function and induce cell apoptosis. It can also inhibit hyaluronidase and protect collagen from the free radical that can be degraded.

Plant origin

Base source
The dry roots, stems, leaves and flowers of the Compositae.

Plant morphology
Perennial herb, 40~120 cm high, with a gray whiteplant. The root is hypertrophy.Stems are erect, prismatic and hollow. The branches are skewed and  thick at the apex with sparsely coarse hair or sericite and rarely no hair case.The basal leaves and the lower leaves of the stem split in the form ofupside pinniform down to the whole, 5~11 cm long and 1~2 cm wide. Apex lobes are larger and lateral lobes are triangular. Basal part is gradually narrowed into winged petioles; Stem leaves are sessile and the leaves gradually become smaller witha small number. Lanceolate ovate to lanceolate and the upper leaves are small. Below all the leaves are sparsely coarse hair or sericite. For the capitulum inflorescence single stem and branch end, 2~3 will cluster in the upper middle axillary fascicles; Involucre is cylindrical, 8~14 mm long; The outer layer of the involucre is of different shapes and lengths. The length of the length is different. The lower part feels like soft leather with lashes and hairy or non-hairy outside. All the flowers are ligulate and the Corolla is blue. The apex of the achenes is truncated and pappus is short, shaping like Scale and the apex is finely toothed. The flowering period is from July to August, and the fruit period is September.

Habitat and distribution
It grows in the foot of the mountain wetland, the beach barren hills and other places. It is produced in Shenyang, Dalian and other cities.
Chicory
Figure 1 Chicory

Stability

  • The effect of pH value on the stability of chicory acid
The effects of different pH on the stability of chicory are different. The degradation rate of chicory acid in strong acid environment is lower than that in weak alkali environment.
  • The effect of temperature on the stability
The high temperature leads to the accelerated degradation of chicory acid, and the low temperature is beneficial to the stability of chicory.
  • The effect of metal ions on the stability
Na+ and K+ did not react with chicory acid; But the reaction of chicory with CaCl2 solution is very rapid, and the mechanism of yellowing of the solution remains to be further explored.The complexity of the food system leads to the mixing of various metal ions. Other metal ions, such as Ca2+, may have a great effect on chicory acid. When chicory acid is applied to food, we should consider the effect of metal ions on chicory acid in liquid food environment or in the post-flush environment so as to avoid the reaction resulting in the degradation of chicory acid and the changes of food quality.
  • Effect of UV on the stability of chicory acid
In methanol, chicory is more susceptible to ultraviolet light and isomerization into icricicory. The conversion rate of isomerization of chicory is higher because the polarity of methanol is smaller than that of water.When chicory is used in food, It should be taken into consideration that the sensitivity of chicory acidafter dissolving to ultraviolet light is higher. In the process, contact with ultraviolet light should be reduced.
  • Study on its stability in fruit juice and beverage
The low temperature storage is more favorable to the stability of chicory than the room temperature. At room temperature (25 ℃), cicory acid 15d will be completely decomposed in the water solution, indicating that the beverage system could protect cicory from degradation to some extent. The juice and beverage system itself is very complex. It is indicated that 100 mg vitamin C is added to the system of 445mL, which has antioxidant effect and can protect chicory to a certain extent. Therefore, the concentration of chicory is still at a high level even for 3 months.
  • Study on its stability in milk powder
Milk powder is a representative solid food environment. All the components in water activity is very small and  relatively stable when isolated from air, water vapor and in light avoidance environment. This is for the lack of environmental factors that cause chicory acid degradation. Therefore, the concentration changes of chicory acid are not affected by the time and the milk powder system. In dry and room temperature storage, chicory can remain relatively stable in the milk powder system.
  • Study on its stability in jelly
The jelly system itself is very stable, and its water activity is very small. Chicory can be kept stable for a long time when it is stored under such a relatively closed condition, isolated from oxygen and water vapor.The slight fluctuations in the detection data may be caused by the error of the sample processing.

Uses

Chicoric Acid is an effective inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. Also a class of cannabinomimetics with CB2 receptor-dependent and independent

Uses

Chicoric Acid is an effective inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. Also a class of cannabinomimetics with CB2 receptor-dependent and indep endent

Definition

ChEBI: Chicoric acid is an organooxygen compound. It has a role as a HIV-1 integrase inhibitor and a geroprotector. It is functionally related to a tetracarboxylic acid.

ChicoricAcid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 159)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9641 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10326 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
Apeloa Pharmaceutical Co., Ltd.
+86-0571-87635730 +8615858229168 chem1022@hengdian-group.com China 1469 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9702 58

View Lastest Price from ChicoricAcid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ChicoricAcid; Echinacea extract pictures 2024-04-23 ChicoricAcid; Echinacea extract
6537-80-0
US $0.00 / KG 1KG ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
ChicoricAcid pictures 2022-10-12 ChicoricAcid
6537-80-0
US $1.00 / kg 1kg 99% 5000 Ton Hebei Duling International Trade Co. LTD
ChicoricAcid pictures 2021-07-02 ChicoricAcid
6537-80-0
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • ChicoricAcid pictures
  • ChicoricAcid
    6537-80-0
  • US $1.00 / kg
  • 99%
  • Hebei Duling International Trade Co. LTD
  • ChicoricAcid pictures
  • ChicoricAcid
    6537-80-0
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
(2R,3R)-2,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]butanedioic acid (2R,3R)-2-O,3-O-Bis[3-(3,4-dihydroxyphenyl)acryloyl]tartaric acid [2R,3R,(-)]-2,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]butanedioic acid 2-O,3-O-Bis[3-(3,4-dihydroxyphenyl)propenoyl]-L-tartaric acid Chicoric acid Butanedioic acid, 2,3-bis((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-, (R-(R*,R*))- Dicaffeoyltartaric acid CICHORIENSAURE Chicoric CICHORIC ACID(P) )(AHP Verified) 2,3-Dicaffeoyl-L-tartaric acid (2R,3R)-2,3-bis(((E)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)succinic acid Chicoric acid, 98%, from Echinacea purpurea (L.) Moench Butanedioic acid, 2,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-, (2R,3R)- ChicoricAci (2R,3R)-2,3-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)succinic acid (2R,3R)-2,3-Bis{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}succinic acid Cichoric Acid (P) Purple daisies 6537-80-0 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). Aromatic Phenols standardized herbal extract