2,6-Dimethoxyphenol
- CAS No.
- 91-10-1
- Chemical Name:
- 2,6-Dimethoxyphenol
- Synonyms
- MCP;Phenol, 2,6-dimethoxy-;aldrich;Dimethoxyphenol;2,6-Dimethoxyphenol (syringol);2,6-Dimethoxyphenyl;Natural 2,6-Dimethoxyphenol;1,3-Dimethoxy-2-hydroxybenzene;AHUS2;MIC10
- CBNumber:
- CB0112026
- Molecular Formula:
- C8H10O3
- Molecular Weight:
- 154.16
- MDL Number:
- MFCD00064434
- MOL File:
- 91-10-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 50-57 °C(lit.) |
|---|---|
| Boiling point | 261 °C(lit.) |
| Density | 1.1690 (rough estimate) |
| refractive index | 1.4745 (estimate) |
| FEMA | 3137 | 2,6-DIMETHOXYPHENOL |
| FLAVIS Number | 04.036 | 2,6-Dimethoxyphenol |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Crystalline Powder, Crystals, or Crystalline Solid |
| pka | 9.97±0.10(Predicted) |
| color | Off-white or gray to brown |
| Odor | at 1.00 % in dipropylene glycol. smoky phenolic balsamic bacon powdery woody |
| Odor Type | smoky |
| biological source | synthetic |
| Water Solubility | 2 g/100 mL (13 ºC) |
| JECFA Number | 721 |
| BRN | 1526871 |
| Henry's Law Constant | 3.7×101 mol/(m3Pa) at 25℃, Sagebiel et al. (1992) |
| InChI | 1S/C8H10O3/c1-10-6-4-3-5-7(11-2)8(6)9/h3-5,9H,1-2H3 |
| InChIKey | KLIDCXVFHGNTTM-UHFFFAOYSA-N |
| SMILES | COc1cccc(OC)c1O |
| LogP | 0.77 |
| CAS DataBase Reference | 91-10-1(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | 2,6-DIMETHOXYPHENOL |
| EWG's Food Scores | 1 |
| FDA UNII | 4UQT464H8K |
| NIST Chemistry Reference | Phenol, 2,6-dimethoxy-(91-10-1) |
| EPA Substance Registry System | Phenol, 2,6-dimethoxy- (91-10-1) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| RIDADR | UN 2811 6.1/PG 1 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | SL0900000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29095090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
2,6-Dimethoxyphenol price More Price(86)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W313726 | 2,6-Dimethoxyphenol natural, ≥96% | 91-10-1 | 1 each | $66 | 2026-04-30 | Buy |
| Sigma-Aldrich | W313726 | 2,6-Dimethoxyphenol natural, ≥96% | 91-10-1 | 100g | $446 | 2026-04-30 | Buy |
| Sigma-Aldrich | W313718 | 2,6-Dimethoxyphenol ≥98%, FG | 91-10-1 | 1 each | $58 | 2026-04-30 | Buy |
| Sigma-Aldrich | W313726 | 2,6-Dimethoxyphenol natural, ≥96% | 91-10-1 | 1kg | $2880 | 2026-04-30 | Buy |
| Sigma-Aldrich | W313718 | 2,6-Dimethoxyphenol ≥98%, FG | 91-10-1 | 100g | $147 | 2026-04-30 | Buy |
2,6-Dimethoxyphenol Chemical Properties, Uses, Production
Chemical Properties
2,6-Dimethoxyphenol is an off-white or grey to brown crystalline powder that has a woody, medicinal, rather dry odor.
Occurrence
Reported found in beechwood tar creosote, onion, garlic, leek, chive, nira (Allium tuberosum Rotti), nobira (Allium grayi Regal) and caucus (Allium victoralis L.)
Uses
2,6-Dimethoxyphenol has been used as a metabolite of lignin depolymerisation.It is also used as flavoring agent or adjuvant.It is reported to be the single most important flavor chemical in smoke flavors. It is used in smoke flavors, whisky, rum, tea, spice, savory, seafood, meat, liquorices, coffee, and nut flavors.
Preparation
2,6-Dimethoxyphenol is prepared by reacting pyrogallol with methyl iodide in alkaline aqueous medium; by demethylation of pyrogallol trimethyl ether in aqueous alkali or in alcohol.
Definition
ChEBI: 2,6-dimethoxyphenol is a member of the class of phenols that is phenol substituted by methoxy groups at positions 2 and 6. It has a role as a plant metabolite. It is a member of phenols and a dimethoxybenzene.
Aroma threshold values
Detection: 400 ppb to 1.85 ppm
Taste threshold values
Taste characteristics at 60 ppm: sweet, medicinal, creamy, meaty, vanilla, spice.
Synthesis Reference(s)
The Journal of Organic Chemistry, 44, p. 4444, 1979 DOI: 10.1021/jo01338a043
Tetrahedron Letters, 34, p. 7667, 1993 DOI: 10.1016/S0040-4039(00)61534-4
General Description
2,6-Dimethoxyphenol has been identified as one of the volatile flavor constituents in shoyu (soy sauce), wine and wood smoke.
Purification Methods
Purify the phenol by zone melting or sublimation in a vacuum. [Beilstein 6 IV 7329.]
2,6-Dimethoxyphenol Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Mingchem Corporation | 0519-85170101 | sales@mingchem.com | China | 633 | 55 |
| Taian Jiayue Bio-chemical Co. LTD | 15318151873 | 285424065@qq.com | China | 4541 | 58 |
| Wuhan Penglei Biological Technology Co., Ltd. | 18672616696 | 229092275@qq.com | China | 706 | 58 |
| Wuhan haorong Biotechnology Co., Ltd | 18186132299 18186132299 | 489527785@qq.com | China | 2688 | 58 |
| Jiangxi Linyuan Spicse Co., Ltd. | 13879661494 13879661494 | 3099857507@qq.com | China | 377 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 45000 | 61 |
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View Latest Price from 2,6-Dimethoxyphenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-10-10 | 2,6-Dimethoxyphenol
91-10-1
|
$25.00 | 1KG | 99.00% | 20MT | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-10-08 | Natural 2,6-Dimethoxyphenol
91-10-1
|
1kg | 99% | 20tons | Sinoway Industrial co., ltd. | ||
 |
2026-05-22 | Natural 2,6-Dimethoxyphenol
91-10-1
|
$5.00 | 1kg | 99% | 1000 kg | BINBOBIO CO., LTD. |
-
- 2,6-Dimethoxyphenol
91-10-1
- $25.00
- 99.00%
- Shaanxi Dideu Medichem Co. Ltd
-
- Natural 2,6-Dimethoxyphenol
91-10-1
- 99%
- Sinoway Industrial co., ltd.
-
- Natural 2,6-Dimethoxyphenol
91-10-1
- $5.00
- 99%
- BINBOBIO CO., LTD.
