2-Methyl-2-propyl-1,3-propanediol
- CAS No.
- 78-26-2
- Chemical Name:
- 2-Methyl-2-propyl-1,3-propanediol
- Synonyms
- DURANOL;NSC 26233;Dimethylolpentane,97%;Pentane-2,2-dimethanol;2,2-DIMETHYLOL-PENTANE;Carisoprodol iMpurity C;Carisoprodol EP Impurity C;Carisoprodol intermediate H;2,2-BIS(HYDROXYMETHYL)PENTANE;2-methyl-2-propyl-3-propanediol
- CBNumber:
- CB0114707
- Molecular Formula:
- C7H16O2
- Molecular Weight:
- 132.2
- MDL Number:
- MFCD00004696
- MOL File:
- 78-26-2.mol
- MSDS File:
- SDS
| Melting point | 57-59 °C (lit.) |
|---|---|
| Boiling point | 230 °C/753 mmHg (lit.) |
| Density | 0.9744 (rough estimate) |
| refractive index | 1.4474 (estimate) |
| Flash point | >230 °F |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 14.57±0.10(Predicted) |
| color | White |
| BRN | 1734432 |
| CAS DataBase Reference | 78-26-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | YLM5KRU0P4 |
| NIST Chemistry Reference | 1,3-Propanediol, 2-methyl-2-propyl-(78-26-2) |
| EPA Substance Registry System | 1,3-Propanediol, 2-methyl-2-propyl- (78-26-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312+P330-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36-22 | |||||||||
| Safety Statements | 22-24/25-39-26 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | TY9386000 | |||||||||
| HS Code | 2905399590 | |||||||||
| NFPA 704 |
|
2-Methyl-2-propyl-1,3-propanediol price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M75209 | 2-Methyl-2-propyl-1,3-propanediol 98% | 78-26-2 | 25g | $46.8 | 2024-03-01 | Buy |
| TCI Chemical | D0766 | 2-Methyl-2-propyl-1,3-propanediol >98.0%(GC) | 78-26-2 | 25g | $23 | 2024-03-01 | Buy |
| TCI Chemical | D0766 | 2-Methyl-2-propyl-1,3-propanediol >98.0%(GC) | 78-26-2 | 500g | $218 | 2024-03-01 | Buy |
| Usbiological | 282563 | 2-Methyl-2-propyl-1,3-propanediol | 78-26-2 | 25g | $292 | 2021-12-16 | Buy |
| TRC | M320590 | 2-Methyl-2-propyl-1,3-propanediol | 78-26-2 | 250g | $155 | 2021-12-16 | Buy |
2-Methyl-2-propyl-1,3-propanediol Chemical Properties,Uses,Production
Synthesis
2-Methyl-2-pentenal was hydrogenated at 100°C and 1.3-1.5MPa with a yield of 80%. After obtaining 2-methylpentenal, it was added to 36% formaldehyde, and the reaction was carried out at room temperature. Sodium hydroxide solution was added dropwise. The reaction was exothermic, and the temperature was naturally raised to 70 °C, then heated to 90 °C, added for 1 h, cooled to 60 °C and left to separate layers. The upper layer was washed with water, the washings were combined with the lower layer, and extracted with benzene. The extract and the upper layer were combined, and benzene was recovered by distillation, followed by distillation under reduced pressure to collect a fraction at 160°C (14.7kPa), which was 2-methyl-2-propyl-1,3-propanediol,yield 93%.
Description
2-Methyl-2-propyl-1,3-propanediol is produced either by the salt-free procedure based on aldol addition followed by hydrogenation or by the classical combination of hydroxymethylation and Cannizzaro-type disproportionation with formaldehyde. The production costs are considerably higher than for neopentyl glycol, because the synthesis of 2-methylpentanal from propanal requires two additional steps: aldol condensation and hydrogenation.
Chemical Properties
Whgite Crystalline Solid
Uses
An intermediate in the synthesis of Carisoprodol.
Uses
2-Methyl-2-propyl-1,3-propanediol is mainly used in pharmaceutical applications such as production of dicarbamates. Meprobamate (2-methyl-2-propyl-1,3-propanediol dicarbamate), is used as an anxiolytic drug (tranquilizer). Carisoprodol (N-isopropyl-2-methyl-2-propyl-1,3-propanediol dicarbamate), possesses strong centrally-acting muscle relaxant activity.
2-Methyl-2-propyl-1,3-propanediol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Ensky Pharmaceutical Co.,Ltd. | +86-23-86815286 +86-13983794297 | sales@ensky-chemical.com | China | 87 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 925 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 7836 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Wuhan Monad Medicine Tech Co.,LTD | 02768782018 18771942761 | sales01@whmonad.com | CHINA | 992 | 58 |
| Hebei Zhanyao Biotechnology Co. Ltd | 15369953316 +8615369953316 | admin@zhanyaobio.com | China | 2136 | 58 |
View Lastest Price from 2-Methyl-2-propyl-1,3-propanediol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-09-20 | 2-Methyl-2-propyl-1,3-propanediol
78-26-2
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-10-12 | 2-Methyl-2-Propyl-1,3-Propanediol
78-26-2
|
US $10.00 / Kg/Bag | 1Kg/Bag | 99% | 20 tons | Hebei Zhanyao Biotechnology Co. Ltd | |
 |
2021-08-31 | 2-Methyl-2-propyl-1,3-propanediol
78-26-2
|
US $10.00 / KG | 25Kg/Drum | 99.99% | 20 tons/month | Wuhan Monad Medicine Tech Co.,LTD |
-
- 2-Methyl-2-propyl-1,3-propanediol
78-26-2
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-Methyl-2-Propyl-1,3-Propanediol
78-26-2
- US $10.00 / Kg/Bag
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
-
- 2-Methyl-2-propyl-1,3-propanediol
78-26-2
- US $10.00 / KG
- 99.99%
- Wuhan Monad Medicine Tech Co.,LTD
78-26-2(2-Methyl-2-propyl-1,3-propanediol)Related Search:
1of4