Artemisinin-d3
- CAS No.
- 176652-07-6
- Chemical Name:
- Artemisinin-d3
- Synonyms
- QHS-d3;Artemisine-d3;Arteannuin-d3;Artemisinin-d3;Huanghuahaosu-d3;[2H3]-Artemisinin;(3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6-dimethyl-9-(methyl-d3)-3,12-epox-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one;3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one, octahydro-3,6-dimethyl-9-(methyl-d3)-, [3R-(3α,5aβ,6β,8aβ,9α,12β,12aR*)]- (9CI);3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one, octahydro-3,6-dimethyl-9-(methyl-d3)-, [3R-(3α,5aβ,6β,8aβ,9α,12β,12aR*)]- (9CI)
- CBNumber:
- CB01176133
- Molecular Formula:
- C15H22O5
- Molecular Weight:
- 282.33218
- MDL Number:
- MOL File:
- 176652-07-6.mol
| Melting point | 156-157°C |
|---|---|
| storage temp. | -20°C Freezer |
| solubility | DMSO: Slightly soluble,Methanol: Slightly soluble |
| form | A solid |
| CAS DataBase Reference | 176652-07-6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H242-H400-H410 | |||||||||
| Precautionary statements | P210-P220-P234-P273-P280-P391-P410-P411+P235-P420-P501 | |||||||||
| NFPA 704 |
|
Artemisinin-d3 price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25359 | Artemisinin-d3 ≥99% deuterated forms (d1-d3) | 176652-07-6 | 1mg | $485 | 2024-03-01 | Buy |
| Usbiological | 002878 | Artemisinin-d3 | 176652-07-6 | 1mg | $566 | 2021-12-16 | Buy |
| TRC | A777502 | Artemisinin-d3 | 176652-07-6 | 10mg | $2180 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BAR0003036 | ARTEMISININ-D3 95.00% | 176652-07-6 | 5MG | $501.36 | 2021-12-16 | Buy |
| aablocks | AA0024Q4 | 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one,octahydro-3,6-dimethyl-9-(methyl-d3)-,[3R-(3α,5aβ,6β,8aβ,9α,12β,12aR*)]-(9CI) ≥99%deuteratedforms(d1-d3) | 176652-07-6 | 5mg | $2038 | 2021-12-16 | Buy |
Artemisinin-d3 Chemical Properties,Uses,Production
Description
Artemisinin-d3 is intended for use as an internal standard for the quantification of artemisinin . Artemisinin is an endoperoxide antimalarial agent with anticancer activity. It reduces the growth of various P. falciparum strains in vitro (IC50s = 3.98-20.36 nM) and reduces parasitemia in mice infected with P. falciparum with a curative dose (CD50) value of 140 mg/kg. It also reduces P. berghei infection in mice (ED50 = 5.6 mg/kg per day). Artemisinin (100-400 μM) induces cell cycle arrest in the G0/G1 phase and apoptosis and inhibits growth of SK-N-AS, BE(2)-C, SK-N-DZ, and SHEP1 neuroblastoma cells in a time- and concentration-dependent manner. It also suppresses BE(2)-C cell colony formation in a soft agar assay and reduces tumor growth in a BE(2)-C mouse xenograft model. Formulations containing artemisinin have been used in combination therapies for the treatment of malaria.
Chemical Properties
Crystalline Solid
Uses
Active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial
Artemisinin-d3 Preparation Products And Raw materials
Raw materials
Preparation Products
Artemisinin-d3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| Nanjing wangzhixing Pharmaceutical Technology Co., Ltd | 15850510341 13101896326 | shiqingran@wzxchem.com | China | 1967 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| Hubei Aiputi Bioengineering Co., Ltd. | 17762444226 | d17762444226@163.com | China | 2402 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | cindy.yang@lgcgroup.com | China | 11437 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7984 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
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