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2-Methoxybenzonitrile

CAS No.
6609-56-9
Chemical Name:
2-Methoxybenzonitrile
Synonyms
AKOS 91422;AKOS B005792;O-CYANOANISOLE;2-CYANOANISOLE;o-Anisonitrile;2-Methxybenzonitrile;2-Methoxybenzonitril;2-METHOXYBENZONITRILE;O-METHOXYBENZONITRILE;2-methoxybnezonitrile
CBNumber:
CB0126249
Molecular Formula:
C8H7NO
Molecular Weight:
133.15
MDL Number:
MFCD00001783
MOL File:
6609-56-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:05:42

2-Methoxybenzonitrile Properties

Melting point 24.5°C
Boiling point 135 °C12 mm Hg(lit.)
Density 1.093 g/mL at 25 °C(lit.)
refractive index n20/D 1.5465(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
Water Solubility Slightly soluble in water
form Liquid
color Clear colorless to pale yellow
BRN 2207134
InChI InChI=1S/C8H7NO/c1-10-8-5-3-2-4-7(8)6-9/h2-5H,1H3
InChIKey FSTPMFASNVISBU-UHFFFAOYSA-N
SMILES C(#N)C1=CC=CC=C1OC
CAS DataBase Reference 6609-56-9(CAS DataBase Reference)
NIST Chemistry Reference o-Methoxybenzonitrile(6609-56-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
RIDADR  3276
WGK Germany  3
HazardClass  6.1
PackingGroup  III
HS Code  29269090
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

2-Methoxybenzonitrile price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 231231 2-Methoxybenzonitrile 99% 6609-56-9 5g $61.6 2023-06-20 Buy
Sigma-Aldrich 231231 2-Methoxybenzonitrile 99% 6609-56-9 25g $132 2023-06-20 Buy
TCI Chemical M1280 2-Methoxybenzonitrile >98.0%(GC) 6609-56-9 5g $52 2026-04-30 Buy
TCI Chemical M1280 2-Methoxybenzonitrile >98.0%(GC) 6609-56-9 25g $159 2026-04-30 Buy
Biosynth FM00412 2-Methoxybenzonitrile 6609-56-9 50g $181 2026-06-04 Buy
Product number Packaging Price Buy
231231 5g $61.6 Buy
231231 25g $132 Buy
M1280 5g $52 Buy
M1280 25g $159 Buy
FM00412 50g $181 Buy

2-Methoxybenzonitrile Chemical Properties, Uses, Production

Chemical Properties

Colorless liquid

Uses

2-Methoxybenzonitrile was used in the synthesis of 5-(4′-methyl [1,1′-biphenyl]-2-yl)-1H-tetrazole.

Preparation

o-Anisidine with sodium nitrite to make a diazonium salt solution, add it to the lead cyanide solution, and then add benzene. Put the mixture for 10-15h and carry out steam distillation, separate the benzene layer from the distillate, dry it with calcium chloride, evaporate the benzene, and distill the residue under reduced pressure, collect 120-122.5°C (1.2kPa fraction) to get 2-Methoxybenzonitrile, yield 64.5-67.3%.

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 109, 1955 DOI: 10.1021/ja01606a035
Synthesis, p. 641, 1992
Tetrahedron Letters, 32, p. 1007, 1991 DOI: 10.1016/S0040-4039(00)74473-X

General Description

Surface-enhanced Raman spectra study of 2-methoxybenzonitrile has been reported.

135-02-4
6609-56-9
Synthesis of 2-Methoxybenzonitrile from o-Anisaldehyde
Global Suppliers ( 252)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44852 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Adamas Reagent, Ltd. 4006009262 13023226327 hmj@titansci.com China 14098 59
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64

View Latest Price from 2-Methoxybenzonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methoxybenzonitrile pictures 2026-09-02 2-Methoxybenzonitrile
6609-56-9
$1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
2-Methoxybenzonitrile pictures 2026-05-28 2-Methoxybenzonitrile
6609-56-9
$9.00 1KG 99% 100000kg Hebei Chuanghai Biotechnology Co,.LTD
2-Methoxybenzonitrile pictures 2026-03-20 2-Methoxybenzonitrile
6609-56-9
$8.90 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
O-CYANOANISOLE O-METHOXYBENZONITRILE 1-Cyano-2-methoxybenzene 2-Methoxybenzonitrile,98% 2-Cyanoanisole, o-Anisonitrile AKOS B005792 AKOS 91422 2-METHOXYBENZONITRILE 2-CYANOANISOLE Benzonitrile, 2-methoxy- Methyl 2-cyanophenyl ether 2-methoxybenzenecarbonitrile o-Anisonitrile 2-Methoxybenzonitrile o-Methoxybenzonitrile 2-methoxybnezonitrile 2-Methxybenzonitrile 2-Methoxybenzonitrile ,97% 2-Methoxybenzonitril 2-Methoxybenzonitrile> 2-Methoxybenzonitrile ISO 9001:2015 REACH 2-(METHOXY-D3)BENZONITRILE 2-Methoxybenzene cyanocyanide 6609-56-9 135550-50-0 151201-51-6 Organic Building Blocks Nitrogen Compounds Cyanides/Nitriles C8 to C9 Building Blocks Aromatic Nitriles Nitriles C8 to C9 Cyanides/Nitriles Nitrogen Compounds