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(S)-(-)-2-Azetidinecarboxylic acid

(S)-(-)-2-Azetidinecarboxylic acid structure

CAS No.: 2133-34-8

Chemical Name:: (S)-(-)-2-Azetidinecarboxylic acid

Synonyms: (S)-AZETIDINE-2-CARBOXYLIC ACID;H-AZE-OH;L-AZETIDINE-2-CARBOXYLIC ACID;L-H-Aze-OH;H-AZE(2)-OH;(S)-(-)-2-Azetidinec;N,3-Methylene-L-alanine;L-AZETIDINECARBOXYLIC ACID;l-2-azetidinecarboxylicaci;azetidyl-2-carboxylic acid

CBNumber:: CB0128117

Molecular Formula:: C4H7NO2

Molecular Weight:: 101.1

MDL Number:: MFCD00005166

MOL File:: 2133-34-8.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:08

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(S)-(-)-2-Azetidinecarboxylic acid Properties

Melting point	~215 °C (dec.)
alpha	-125 º (c=1, water 25 ºC)
Boiling point	189.47°C (rough estimate)
Density	1.2245 (rough estimate)
refractive index	-122 ° (C=4, H2O)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
pka	2.35±0.20(Predicted)
form	Crystalline Powder or Crystals
color	White to light beige
Water Solubility	5 g/100 mL
Merck	14,908
BRN	80678
InChIKey	IADUEWIQBXOCDZ-VKHMYHEASA-N
CAS DataBase Reference	2133-34-8(CAS DataBase Reference)
FDA UNII	5GZ3E0L9ZU

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

24/25-36-26

WGK Germany

RTECS

CM4310500

Hazard Note

Irritant

HS Code

29339900

Toxicity

LD50 scu-mus: 1000 mg/kg 85GDA2 8(1),101,82

NFPA 704

	1
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(S)-(-)-2-Azetidinecarboxylic acid price More Price(56)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A0760	L-Azetidine-2-carboxylic acid ≥99%	2133-34-8	50mg	$85.9	2024-03-01	Buy
Sigma-Aldrich	A0760	L-Azetidine-2-carboxylic acid ≥99%	2133-34-8	1g	$711	2024-03-01	Buy
TCI Chemical	A1043	L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline] >98.0%(T)	2133-34-8	1g	$279	2024-03-01	Buy
TCI Chemical	A1043	L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline] >98.0%(T)	2133-34-8	100mg	$49	2024-03-01	Buy
Alfa Aesar	L09668	(S)-(-)-Azetidine-2-carboxylic acid, 98%	2133-34-8	250mg	$120.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
A0760	50mg	$85.9	Buy
A0760	1g	$711	Buy
A1043	1g	$279	Buy
A1043	100mg	$49	Buy
L09668	250mg	$120.65	Buy

(S)-(-)-2-Azetidinecarboxylic acid Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

L-Azetidine-2-carboxylic acid has been used as a:

collagen synthesis inhibitor
protein folding antagonist
as a standard in liquid chromatography-mass spectrometry

Uses

Specific proline antagonist. Used in synthesis of abnormally high molecular weight polypeptides.

Uses

(S)-(-)-2-Azetidinecarboxylic acid is a four-membered ring analog of L-Proline, It is a useful intermediate in the synthesis of polypeptides,Used in synthesis of abnormally high molecular weight polypeptides.

Definition

ChEBI: The (S)-enantiomer of azetidine-2-carboxylic acid.

General Description

L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.

Biochem/physiol Actions

Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.

Safety Profile

Moderately toxic by subcutaneousroute. An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits toxic fumes of NOx.

(S)-(-)-2-Azetidinecarboxylic acid Preparation Products And Raw materials

Raw materials

Potassium tert-butoxide Acetonitrile 2-Bromoethanol Potassium carbonate Palladium

L-1-Phenylethylamine Tetrahydrofuran Diethyl ether Ammonium chloride Ethyl acetate

Hydrochloric acid Bromoacetonitrile Sodium bicarbonate Dichloromethane Methanol

Dimethyl sulfoxide Thionyl chloride PETROLEUM ETHER

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Preparation Products

(S)-(-)-2-Azetidinecarboxylic acid Suppliers

Global( 327)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	724	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Chengdu Pukang Biotechnology Co., Ltd	028-82550498	export@pu-kang.com	CHINA	210	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	info@edengenechem.com	China	2169	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Chembon Pharmaceutical Co., Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
Chengdu Pukang Biotechnology Co., Ltd	58
Changzhou Ditong Chemical Co.,Ltd	58

View Lastest Price from (S)-(-)-2-Azetidinecarboxylic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-07-27	(S)-(-)-2-Azetidinecarboxylic acid 2133-34-8	US $1.50 / g	1g	99.0% Min	100 Tons	Shaanxi Didu New Materials Co. Ltd
2022-01-27	(S)-L-Azetidine-2-carboxylic acid 2133-34-8	US $0.00 / KG	1KG	98.0%	100 tons	Honest Joy Holdings Limited
2021-08-11	(S)-(-)-2-Azetidinecarboxylic acid 2133-34-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

(S)-(-)-2-Azetidinecarboxylic acid
2133-34-8
US $1.50 / g
99.0% Min
Shaanxi Didu New Materials Co. Ltd

(S)-L-Azetidine-2-carboxylic acid
2133-34-8
US $0.00 / KG
98.0%
Honest Joy Holdings Limited

(S)-(-)-2-Azetidinecarboxylic acid
2133-34-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

(S)-(-)-2-Azetidinecarboxylic acid Spectrum

(S)-(-)-2-Azetidinecarboxylic acid(2133-34-8)¹HNMR (S)-(-)-2-Azetidinecarboxylic acid(2133-34-8)FT-IR (S)-(-)-2-Azetidinecarboxylic acid(2133-34-8)IR (S)-(-)-2-Azetidinecarboxylic acid(2133-34-8)Raman

2133-34-8((S)-(-)-2-Azetidinecarboxylic acid)Related Search:

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Azetidine n-Butane Salbutamol 1-Chloro-2-methylpropane 3-Azetidinecarboxylic acid

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(S)-(-)-2-AZETIDINECARBOXYLIC ACID (S)-2-AZETIDINE CARBOXYLIC ACID (S)-(-)-AZETIDINE-2-CARBOXYLIC ACID (S)-L-2-AZETIDINE CARBOXYLIC ACID (2S)-(-)-AZETIDINE-2-CARBOXYLIC ACID L-TRIMETHYLENEIMINE-2-CARBOXYLIC ACID L-AZETIDINECARBOXYLIC ACID L-2-AZETIDINECARBOXYLIC ACID H-AZE(2)-OH (S)-Azetidine-2-carboxylic acid, L-2-Azetidinecarboxylic acid, L-Azetidine-2-carboxylic acid (2S)-2-Azetidinecarboxylic acid N,3-Methylene-L-alanine (s)-2-azetidinecarboxylicaci 2-Azetidinecarboxylic acid, (2S)- L-Azetidine-2-carboxylic acid ,98% L-Azetidine-2-carboxylic acid ,99% (S)-(-)-2-Azetidinec (S)-(-) Azetidine-2-carbo... (S)-L-Azetidine-2-carboxylic acid (S) - (-) - 2- carboxy cyclobutylaMine (S)-2-Azetidine-2-carboxylic acid L-Azetidine-2-carboxylic acid≥ 97% (Assay) acidel-azetidine-2-carboxylic acidel-azetidine-2-carboxylic(french) l-2-azetidinecarboxylicaci l-azetidine-2-carboxylicaci L-AZETIDINE-2-CARBOXYLIC ACID*CRYSTALLIN E (S)-(-)-2-AZETIDINECARBOXYLIC ACID, 99+% (S)-(-)-2-Azetidinecarboxylic azetidyl-2-carboxylic acid L-H-Aze-OH L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline] L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]> (S)-(-)-2-Azetidinecarboxylic acid ISO 9001：2015 REACH (S)-AZETIDINE-2-CARBOXYLIC ACID L-AZETIDINE-2-CARBOXYLIC ACID H-AZE-OH (S)-Azetidine-2-carboxylic acid/(S)-2-Azetidine carboxylic acid/L-Azetidine-2-carboxylic acid (S)-azetidine-2-carboxylicaci (-)-Azetidinecarboxylic acid (S)-Azetidine carboxylic acid 2133-34-8 Chiral Building Blocks Carboxylic Acids (Chiral) Simple 4-Membered Ring Compounds Azetidines Cell Biology Angiogenesis Regulators BioChemical Cell Signaling and Neuroscience Extracellular Matrix Cytoskeleton and Extracellular Matrix Others Peptide Synthesis Unnatural Amino Acid Derivatives Specialty Synthesis Amino Acids 13C, 2H, 15N Carboxylic Acids (Chiral)