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6-ANILINO-5,8-QUINOLINEDIONE

6-ANILINO-5,8-QUINOLINEDIONE
6-ANILINO-5,8-QUINOLINEDIONE
CAS No.
91300-60-6
Chemical Name:
6-ANILINO-5,8-QUINOLINEDIONE
Synonyms
LY 83583;6-ANILINO-5,8-QUINOLINEDIONE;6-(anilino)quinoline-5,8-dione;6-ANILINOQUINOLINE-5,8-QUINONE;6-ANILINO-5,8-QUINOLINEQUINONE;6-(PHENYLAMINO)-5,8-QUINOLINEDIONE;6-(phenylamino)quinoline-5,8-dione;5,8-Dihydro-5,8-dioxo-6-(phenylaMino)quinoline;6-(Phenylamino)-5,8-quinolinedione, LY-83,583;5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline, [(5,8-Dihydro-5,8-dioxoquinolin-6-yl)amino]benzene, 6-Anilinoquinoline-5,8-dione
CBNumber:
CB0130280
Molecular Formula:
C15H10N2O2
Formula Weight:
250.25
MOL File:
91300-60-6.mol

6-ANILINO-5,8-QUINOLINEDIONE Properties

Melting point:
184-185°C
storage temp. 
2-8°C
solubility 
0.1 M HCl: 1 mg/mL
form 
solid
color 
violet
CAS DataBase Reference
91300-60-6(CAS DataBase Reference)

SAFETY

Hazard Codes  Xn,Xi
Risk Statements  40-36/37/38
Safety Statements  36/37-36-26
WGK Germany  2

6-ANILINO-5,8-QUINOLINEDIONE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 440205-M LY 83583 91300-60-6 5mg-m $96.8 2018-11-20 Buy
Sigma-Aldrich A6563 6-Anilinoquinoline-5,8-quinone ≥95% (TLC), solid 91300-60-6 5mg $133 2018-11-20 Buy
Cayman Chemical 70230 LY83583 ≥99% 91300-60-6 1mg $13 2018-11-13 Buy
Cayman Chemical 70230 LY83583 ≥99% 91300-60-6 5mg $52 2018-11-13 Buy
Cayman Chemical 70230 LY83583 ≥99% 91300-60-6 10mg $78 2018-11-13 Buy

6-ANILINO-5,8-QUINOLINEDIONE Chemical Properties,Uses,Production

Chemical Properties

Red-Brown Solid

Uses

Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release

Uses

Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2μM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release.

Definition

ChEBI: A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group.

Uses

LY83583 is an inhibitor of soluble guanylate cyclase and of cGMP production. It inhibits soluble guanylate cyclase in human platelets with an IC50 value of 2 μM. LY83583 also inhibits leukotriene synthesis in guinea pig lung and rat peritoneal cells with an IC50 value of 1.8 μM and is a noncompetitive inhibitor of glutathione reductase in bovine intestinal mucosa with a Ki value of 3 μM.[Cayman Chemical]

6-ANILINO-5,8-QUINOLINEDIONE Preparation Products And Raw materials

Raw materials

Preparation Products


6-ANILINO-5,8-QUINOLINEDIONE Suppliers

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91300-60-6(6-ANILINO-5,8-QUINOLINEDIONE)Related Search:


  • LY 83583
  • 6-(PHENYLAMINO)-5,8-QUINOLINEDIONE
  • 6-ANILINO-5,8-QUINOLINEDIONE
  • 6-(Phenylamino)-5,8-quinolinedione, LY-83,583
  • 6-(anilino)quinoline-5,8-dione
  • 6-(phenylamino)quinoline-5,8-dione
  • 5,8-Dihydro-5,8-dioxo-6-(phenylaMino)quinoline
  • 6-ANILINO-5,8-QUINOLINEQUINONE
  • 6-ANILINOQUINOLINE-5,8-QUINONE
  • 5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline, [(5,8-Dihydro-5,8-dioxoquinolin-6-yl)amino]benzene, 6-Anilinoquinoline-5,8-dione
  • Aromatics
  • 91300-60-6
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Cyclic Nucleotide Metabolism
  • Guanylyl Cyclase Inhibitors
  • G Proteins and Cyclic Nucleotides
  • All Inhibitors
  • Inhibitors
  • Nitric Oxide Reagents
  • Heterocycles
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